| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0966606 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0870175 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0680835 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0628596 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0565855 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0529723 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0482415 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0439388 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.041895 |
| UBC | ubiquitin C | 0.0411958 |
| RPS27A | ribosomal protein S27a | 0.0385005 |
| MCL1 | myeloid cell leukemia 1 | 0.0371346 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0368998 |
| TMEM41B | transmembrane protein 41B | 0.0356336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0355995 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0350075 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0334069 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0317649 |
| RPL37A | ribosomal protein L37a | 0.0307396 |
| YBX3 | Y box binding protein 3 | 0.0305192 |
| OGA | O-GlcNAcase | 0.0302915 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0290901 |
| RPL4 | ribosomal protein L4 | 0.0289365 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0287277 |
| RPS12 | ribosomal protein S12 | 0.0287162 |
| RPS8 | ribosomal protein S8 | 0.0281889 |
| RPS3 | ribosomal protein S3 | 0.027707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0275806 |
| ACTG1 | actin gamma 1 | 0.0266876 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0265985 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0244038 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0242564 |
| CTTN | cortactin | 0.0230634 |
| RPS29 | ribosomal protein S29 | 0.0226748 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0226646 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0216822 |
| PRKCE | protein kinase C, epsilon | 0.0211598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0207413 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0204594 |
| HOMER1 | homer scaffolding protein 1 | 0.0204254 |
| RPL37 | ribosomal protein L37 | 0.0202915 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0202759 |
| RPS2 | ribosomal protein S2 | 0.0198363 |
| MYO10 | myosin X | 0.0192044 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.019072 |
| IER3 | immediate early response 3 | 0.0187794 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0187625 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0186397 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0185929 |
| DENR | density-regulated protein | 0.0184507 |
| MYPN | myopalladin | 0.0183061 |
| HLA-B | major histocompatibility complex, class I, B | 0.0182446 |
| CAVIN1 | caveolae associated protein 1 | 0.0182014 |
| RPS10 | ribosomal protein S10 | 0.0181883 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0179846 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.017922 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0178353 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0177795 |
| IPO7 | importin 7 | 0.0177514 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0174198 |
| RPL27 | ribosomal protein L27 | 0.0174164 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0168018 |
| PCDH7 | protocadherin 7 | 0.0167351 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0166553 |
| RPLP1 | ribosomal protein, large, P1 | 0.0164443 |
| RPL23 | ribosomal protein L23 | 0.0164409 |
| FMNL2 | formin-like 2 | 0.0159287 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0159117 |
| RPL26 | ribosomal protein L26 | 0.015678 |
| RPL12 | ribosomal protein L12 | 0.015619 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0154966 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0154458 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0154118 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0153539 |
| ATP11A | ATPase, class VI, type 11A | 0.0153325 |
| NRG1 | neuregulin 1 | 0.0153287 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.015174 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0148408 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0147903 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0145798 |
| RPS17 | ribosomal protein S17 | 0.0143538 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0143347 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0142919 |
| RACK1 | receptor for activated C kinase 1 | 0.0142909 |
| RPL9 | ribosomal protein L9 | 0.0142118 |
| PRDX1 | peroxiredoxin 1 | 0.0141182 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0140023 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0136516 |
| TUSC3 | tumor suppressor candidate 3 | 0.0134401 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0134362 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0134048 |
| TCIM | transcriptional and immune response regulator | 0.0133866 |
| VCP | valosin containing protein | 0.0133433 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0133225 |
| PGK1 | phosphoglycerate kinase 1 | 0.0133036 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.013285 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0131361 |
| SQSTM1 | sequestosome 1 | 0.0131193 |
| EHD4 | EH-domain containing 4 | 0.0130395 |
| RTN4 | reticulon 4 | 0.0129353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RAD51B | RAD51 paralog B | -0.14536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.143583 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109631 |
| EGR1 | early growth response 1 | -0.0888494 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0724973 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.071505 |
| BBX | bobby sox homolog (Drosophila) | -0.067532 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0662027 |
| EXOC4 | exocyst complex component 4 | -0.0610048 |
| VIM | vimentin | -0.0600981 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0596549 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0584735 |
| SBF2 | SET binding factor 2 | -0.0563993 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0552921 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0549463 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0528904 |
| TPI1 | triosephosphate isomerase 1 | -0.0518671 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0513045 |
| COPA | coatomer protein complex, subunit alpha | -0.0502713 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0492387 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0491722 |
| EGFR | epidermal growth factor receptor | -0.0491433 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0489053 |
| PFN1 | profilin 1 | -0.0484547 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0482804 |
| RSF1 | remodeling and spacing factor 1 | -0.0481357 |
| SMAD3 | SMAD family member 3 | -0.0471494 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0468542 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0467267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0459674 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.045584 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0455279 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0453188 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0438901 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0435302 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0435297 |
| ZNF292 | zinc finger protein 292 | -0.0428796 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0423191 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0422827 |
| PTMA | prothymosin, alpha | -0.0421241 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0420794 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0420217 |
| POTEF | POTE ankyrin domain family, member F | -0.0420058 |
| SETD5 | SET domain containing 5 | -0.0415999 |
| IGF2 | insulin-like growth factor 2 | -0.0414708 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0413351 |
| WASF2 | WAS protein family, member 2 | -0.0412782 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.041274 |
| PTK2 | protein tyrosine kinase 2 | -0.0411243 |
| NF1 | neurofibromin 1 | -0.0407191 |
| USP34 | ubiquitin specific peptidase 34 | -0.0406974 |
| PHF21A | PHD finger protein 21A | -0.0401111 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0398055 |
| EHBP1 | EH domain binding protein 1 | -0.0393555 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.038951 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0387615 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0385936 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0382246 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0381428 |
| ATXN1 | ataxin 1 | -0.037975 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0375956 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0367542 |
| ATXN2 | ataxin 2 | -0.0364329 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0358553 |
| CANX | calnexin | -0.0358233 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0356988 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0353206 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0353196 |
| MKI67 | marker of proliferation Ki-67 | -0.0349949 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0348797 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0342048 |
| GOLGA4 | golgin A4 | -0.034173 |
| PHF20 | PHD finger protein 20 | -0.0341696 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0340575 |
| HMGA1 | high mobility group AT-hook 1 | -0.0339251 |
| ZNF207 | zinc finger protein 207 | -0.0333887 |
| CENPF | centromere protein F, 350/400kDa | -0.0333096 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0332362 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0331643 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0330659 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.033041 |
| SRBD1 | S1 RNA binding domain 1 | -0.0327704 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0327687 |
| HDGF | hepatoma-derived growth factor | -0.0326911 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0325573 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.03252 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0324538 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0320447 |
| DENND5B | DENN/MADD domain containing 5B | -0.0317005 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0316764 |
| HMGA2 | high mobility group AT-hook 2 | -0.0315134 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0311384 |
| CBX5 | chromobox homolog 5 | -0.0309274 |
| LDHA | lactate dehydrogenase A | -0.0307768 |
| TXNRD1 | thioredoxin reductase 1 | -0.0303925 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0301977 |
| GNAS | GNAS complex locus | -0.0301488 |
| DENND1A | DENN/MADD domain containing 1A | -0.0301223 |
| RNF213 | ring finger protein 213 | -0.03008 |
| BPTF | bromodomain PHD finger transcription factor | -0.029875 |
