| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bergenin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.172758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.16364 |
| NDRG1 | N-myc downstream regulated 1 | 0.109377 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.10663 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0837822 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0751656 |
| FAM13A | family with sequence similarity 13, member A | 0.0586903 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0540786 |
| RPS3 | ribosomal protein S3 | 0.0534991 |
| RPS2 | ribosomal protein S2 | 0.048255 |
| RPL4 | ribosomal protein L4 | 0.0430952 |
| HSPA8 | heat shock 70kDa protein 8 | 0.042648 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0414557 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0401894 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.040063 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039829 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0397341 |
| RACK1 | receptor for activated C kinase 1 | 0.0382561 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.037866 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0363839 |
| RPS12 | ribosomal protein S12 | 0.0362334 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0362284 |
| FTL | ferritin, light polypeptide | 0.0350346 |
| CCNL1 | cyclin L1 | 0.0349562 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0335692 |
| ARRDC3 | arrestin domain containing 3 | 0.0324668 |
| MSN | moesin | 0.0317695 |
| HMGB2 | high mobility group box 2 | 0.0307763 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0304929 |
| RPL37A | ribosomal protein L37a | 0.02936 |
| ANXA1 | annexin A1 | 0.0289678 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0285523 |
| RPL3 | ribosomal protein L3 | 0.0284358 |
| PCBP2 | poly(rC) binding protein 2 | 0.0281059 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0277655 |
| BRD2 | bromodomain containing 2 | 0.0272854 |
| RNF145 | ring finger protein 145 | 0.0272008 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0269346 |
| MT2A | metallothionein 2A | 0.0268597 |
| RPL7 | ribosomal protein L7 | 0.0265875 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0264679 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258541 |
| SGMS2 | sphingomyelin synthase 2 | 0.0252416 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0250037 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0246504 |
| YBX3 | Y box binding protein 3 | 0.023904 |
| PAPOLA | poly(A) polymerase alpha | 0.023821 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0236659 |
| RPS6 | ribosomal protein S6 | 0.0227414 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0226644 |
| NCKAP1 | NCK-associated protein 1 | 0.0224711 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.022456 |
| RPL12 | ribosomal protein L12 | 0.0222907 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0221771 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.02209 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0217473 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0217098 |
| RPL11 | ribosomal protein L11 | 0.0216751 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0213536 |
| RPLP0 | ribosomal protein, large, P0 | 0.0205087 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203598 |
| UPP1 | uridine phosphorylase 1 | 0.0203443 |
| RPS17 | ribosomal protein S17 | 0.0203129 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0203019 |
| RPL9 | ribosomal protein L9 | 0.0199706 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0196033 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0194952 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0194864 |
| RPL32 | ribosomal protein L32 | 0.0193925 |
| RPS8 | ribosomal protein S8 | 0.0192593 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0189671 |
| SDC4 | syndecan 4 | 0.0186942 |
| ACTG1 | actin gamma 1 | 0.0184767 |
| H1-4 | H1.4 linker histone, cluster member | 0.0183449 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0177454 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0175918 |
| RPL27 | ribosomal protein L27 | 0.0175565 |
| RPS27A | ribosomal protein S27a | 0.0174059 |
| TXNRD1 | thioredoxin reductase 1 | 0.0172889 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.017271 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.017143 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0171344 |
| STEAP4 | STEAP family member 4 | 0.0169789 |
| RPS23 | ribosomal protein S23 | 0.016855 |
| SET | SET nuclear proto-oncogene | 0.0168465 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0167202 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.0166672 |
| AREG | amphiregulin | 0.0164103 |
| DSTN | destrin (actin depolymerizing factor) | 0.0163637 |
| ATF4 | activating transcription factor 4 | 0.0162488 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0161966 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0161235 |
| IPO7 | importin 7 | 0.0161024 |
| MKI67 | marker of proliferation Ki-67 | 0.0160801 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0160637 |
| IDS | iduronate 2-sulfatase | 0.0160092 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0159896 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0159364 |
| NPTN | neuroplastin | 0.0158808 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0157681 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.157302 |
| TMSB10 | thymosin beta 10 | -0.131939 |
| GRB10 | growth factor receptor-bound protein 10 | -0.124951 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.114539 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.112567 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0977659 |
| FN1 | fibronectin 1 | -0.0836242 |
| LMO7 | LIM domain 7 | -0.0825657 |
| FBXO32 | F-box protein 32 | -0.082114 |
| ERBIN | erbb2 interacting protein | -0.0768657 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0724895 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0675076 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0661742 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0656709 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0654221 |
| CCND1 | cyclin D1 | -0.0630251 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0622245 |
| CD2AP | CD2-associated protein | -0.0606906 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0602948 |
| RNF213 | ring finger protein 213 | -0.0598323 |
| RAI14 | retinoic acid induced 14 | -0.0570564 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0565515 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0563851 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0553471 |
| TMSB4X | thymosin beta 4, X-linked | -0.0551348 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0551098 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0547272 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0538179 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0537364 |
| VCL | vinculin | -0.0531324 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0526327 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0510078 |
| TPM4 | tropomyosin 4 | -0.0509051 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0507121 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0498282 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0491304 |
| RPL35A | ribosomal protein L35a | -0.049091 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0470015 |
| MYO6 | myosin VI | -0.0465675 |
| FBXO34 | F-box protein 34 | -0.0464312 |
| MSI2 | musashi RNA-binding protein 2 | -0.046323 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0462811 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0461724 |
| POTEF | POTE ankyrin domain family, member F | -0.0461666 |
| EFNA5 | ephrin-A5 | -0.0459297 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0458316 |
| MX2 | MX dynamin-like GTPase 2 | -0.0457728 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0455072 |
| CTBP2 | C-terminal binding protein 2 | -0.0453808 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0450747 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0445645 |
| VEGFA | vascular endothelial growth factor A | -0.0444059 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0442429 |
| RRBP1 | ribosome binding protein 1 | -0.0438798 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0437855 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0436077 |
| PLSCR1 | phospholipid scramblase 1 | -0.0435098 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0428017 |
| RCOR1 | REST corepressor 1 | -0.042663 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0422189 |
| PTK2 | protein tyrosine kinase 2 | -0.0416412 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0414932 |
| MCU | mitochondrial calcium uniporter | -0.0413762 |
| MX1 | MX dynamin-like GTPase 1 | -0.0413324 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0405244 |
| FNIP1 | folliculin interacting protein 1 | -0.0401815 |
| GNAS | GNAS complex locus | -0.0399369 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0397989 |
| MAP4 | microtubule-associated protein 4 | -0.0396707 |
| MYO1E | myosin IE | -0.0392899 |
| NF1 | neurofibromin 1 | -0.0385424 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0380926 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0378913 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0374727 |
| KRT7 | keratin 7, type II | -0.0374322 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.037274 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0371509 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0371316 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0370774 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0364746 |
| GOLGB1 | golgin B1 | -0.0363916 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0363069 |
| RASAL2 | RAS protein activator like 2 | -0.036018 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0359321 |
| CERT1 | ceramide transporter 1 | -0.0358787 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0357968 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0357933 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0355254 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.035276 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0350753 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0346458 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0346379 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0345549 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0344926 |
| DTNA | dystrobrevin, alpha | -0.0341254 |
| ETV6 | ets variant 6 | -0.0339941 |
| PKM | pyruvate kinase, muscle | -0.0338497 |
| HLA-B | major histocompatibility complex, class I, B | -0.0336939 |
| RIGI | RNA sensor RIG-I | -0.033441 |
| RSF1 | remodeling and spacing factor 1 | -0.033355 |
