| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.164255 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.162896 |
| IGF2 | insulin-like growth factor 2 | 0.156715 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.134526 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.114785 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0874453 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0853598 |
| NDRG1 | N-myc downstream regulated 1 | 0.0835532 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0828441 |
| RUNX1 | runt-related transcription factor 1 | 0.0823902 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.077423 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0745018 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0696029 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0645186 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0618195 |
| GPC6 | glypican 6 | 0.0607122 |
| RPL11 | ribosomal protein L11 | 0.0603683 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0533352 |
| VIM | vimentin | 0.0523726 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0521515 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0515701 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0495737 |
| JMJD1C | jumonji domain containing 1C | 0.0492748 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0491286 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0490875 |
| MCL1 | myeloid cell leukemia 1 | 0.0484185 |
| CD109 | CD109 molecule | 0.0481887 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0478726 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0471027 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0466765 |
| RAD51B | RAD51 paralog B | 0.0446578 |
| FAT1 | FAT atypical cadherin 1 | 0.0444593 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0443544 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0421819 |
| EGR1 | early growth response 1 | 0.0412409 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0399862 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0397096 |
| TMEM87A | transmembrane protein 87A | 0.0392315 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0391621 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.038452 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0374266 |
| EHBP1 | EH domain binding protein 1 | 0.0363964 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0359051 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0358266 |
| ASPH | aspartate beta-hydroxylase | 0.035261 |
| FRMD4A | FERM domain containing 4A | 0.0348086 |
| ATXN1 | ataxin 1 | 0.0345262 |
| LDHA | lactate dehydrogenase A | 0.0345094 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0343082 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0343005 |
| ITGA6 | integrin, alpha 6 | 0.0340256 |
| EGFR | epidermal growth factor receptor | 0.0338643 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0336702 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0333445 |
| PTK2 | protein tyrosine kinase 2 | 0.0327447 |
| NAV1 | neuron navigator 1 | 0.0322372 |
| PRELID2 | PRELI domain containing 2 | 0.0315355 |
| NGLY1 | N-glycanase 1 | 0.0314175 |
| SQSTM1 | sequestosome 1 | 0.0310993 |
| MYO1E | myosin IE | 0.0301824 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0301575 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0301298 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0297474 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0295087 |
| RPS8 | ribosomal protein S8 | 0.0291751 |
| NF1 | neurofibromin 1 | 0.0281661 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0280759 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0260946 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0260344 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0258685 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.024937 |
| SNX9 | sorting nexin 9 | 0.0247724 |
| RPS16 | ribosomal protein S16 | 0.0239991 |
| SLTM | SAFB-like, transcription modulator | 0.0234722 |
| MSI2 | musashi RNA-binding protein 2 | 0.0228337 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0227146 |
| RIGI | RNA sensor RIG-I | 0.0226293 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0224208 |
| INHBA | inhibin, beta A | 0.0215198 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0201234 |
| CANX | calnexin | 0.019809 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0197372 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0188695 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0185806 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0185395 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0181183 |
| CDH13 | cadherin 13 | 0.0179821 |
| MYO5B | myosin VB | 0.0179251 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0177463 |
| MAP4 | microtubule-associated protein 4 | 0.0174048 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.017281 |
| FMN1 | formin 1 | 0.0167374 |
| HMGA2 | high mobility group AT-hook 2 | 0.0159646 |
| NAV2 | neuron navigator 2 | 0.0158719 |
| FMNL2 | formin-like 2 | 0.0156203 |
| MED13L | mediator complex subunit 13-like | 0.0152904 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0147935 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0135226 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0132563 |
| SPATA13 | spermatogenesis associated 13 | 0.0132032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.103608 |
| HDLBP | high density lipoprotein binding protein | -0.0974384 |
| ZNF292 | zinc finger protein 292 | -0.0815011 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0710536 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0689873 |
| KIF5B | kinesin family member 5B | -0.0679445 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0663335 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0658966 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0652922 |
| VCL | vinculin | -0.0646267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0630926 |
| CALR | calreticulin | -0.0621821 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0599592 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0599039 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0590371 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0586457 |
| RBM25 | RNA binding motif protein 25 | -0.0556698 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0549062 |
| PDE10A | phosphodiesterase 10A | -0.0522275 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0518606 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0508508 |
| RTN4 | reticulon 4 | -0.0494502 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.047081 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0463438 |
| MORF4L2 | mortality factor 4 like 2 | -0.0448832 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0443038 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0434071 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0433007 |
| RPS24 | ribosomal protein S24 | -0.0418637 |
| GOLGA4 | golgin A4 | -0.0416076 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0415148 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0412196 |
| SMYD3 | SET and MYND domain containing 3 | -0.0406509 |
| LMNA | lamin A/C | -0.0397142 |
| FTL | ferritin, light polypeptide | -0.0396221 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0382863 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0378811 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0374978 |
| SP100 | SP100 nuclear antigen | -0.0373962 |
| PUM2 | pumilio RNA-binding family member 2 | -0.037374 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0371758 |
| LMO7 | LIM domain 7 | -0.0367149 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0362263 |
| TXNIP | thioredoxin interacting protein | -0.0360169 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0358073 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0350963 |
| B2M | beta-2-microglobulin | -0.0346893 |
| TMSB10 | thymosin beta 10 | -0.034178 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0334042 |
| USP34 | ubiquitin specific peptidase 34 | -0.0329174 |
| STC1 | stanniocalcin 1 | -0.0326784 |
| RPL26 | ribosomal protein L26 | -0.0321569 |
| PKM | pyruvate kinase, muscle | -0.0321272 |
| CCNI | cyclin I | -0.0317776 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309882 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0309878 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0307497 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0284229 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0280123 |
| EFNA5 | ephrin-A5 | -0.0268726 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0254366 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.024923 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0248711 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0245755 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0241936 |
| SPAG9 | sperm associated antigen 9 | -0.0238447 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0238017 |
| RACK1 | receptor for activated C kinase 1 | -0.0224917 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0220135 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0211566 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0209007 |
| PRKCA | protein kinase C, alpha | -0.0203167 |
| RPL37 | ribosomal protein L37 | -0.0187511 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0185438 |
| MED13 | mediator complex subunit 13 | -0.0147244 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0140156 |
| RPLP2 | ribosomal protein, large, P2 | -0.0131019 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0123293 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0121744 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0118636 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0117318 |
| RPL37A | ribosomal protein L37a | -0.01172 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0112532 |
| RBM39 | RNA binding motif protein 39 | -0.0108866 |
| ENO1 | enolase 1, (alpha) | -0.010591 |
| RPS19 | ribosomal protein S19 | -0.010104 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.00993093 |
| SVIL | supervillin | -0.00972751 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.00965041 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00924437 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00875026 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.00843546 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.00807266 |
| PTMA | prothymosin, alpha | -0.00807185 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.00797245 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.00620158 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00591464 |
| MT2A | metallothionein 2A | -0.00537795 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.00518353 |
| KRT8 | keratin 8, type II | -0.00504876 |
