| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.196473 |
| VIM | vimentin | 0.136107 |
| HLA-A | major histocompatibility complex, class I, A | 0.122878 |
| CD44 | CD44 molecule (Indian blood group) | 0.105058 |
| HDAC9 | histone deacetylase 9 | 0.104092 |
| STC1 | stanniocalcin 1 | 0.101456 |
| NDRG1 | N-myc downstream regulated 1 | 0.0928146 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0808255 |
| HMGA2 | high mobility group AT-hook 2 | 0.0747849 |
| MT2A | metallothionein 2A | 0.0728386 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0726044 |
| EFNA5 | ephrin-A5 | 0.0712301 |
| RPS12 | ribosomal protein S12 | 0.0695585 |
| RND3 | Rho family GTPase 3 | 0.069384 |
| FTL | ferritin, light polypeptide | 0.0657277 |
| ADM | adrenomedullin | 0.06225 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0613187 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0613179 |
| FMNL2 | formin-like 2 | 0.0544113 |
| C3 | complement component 3 | 0.0543924 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0536752 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0525301 |
| INHBA | inhibin, beta A | 0.050746 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0503371 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0502597 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0500669 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0499699 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0492556 |
| KYNU | kynureninase | 0.0481404 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0477865 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0471298 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0470065 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0468015 |
| PLIN2 | perilipin 2 | 0.0462968 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0462835 |
| SQSTM1 | sequestosome 1 | 0.0452806 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0449267 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0443994 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0443222 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0442877 |
| B2M | beta-2-microglobulin | 0.0442401 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0437614 |
| GLIS3 | GLIS family zinc finger 3 | 0.041187 |
| ASPH | aspartate beta-hydroxylase | 0.0408521 |
| VMP1 | vacuole membrane protein 1 | 0.040659 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0399599 |
| MYO10 | myosin X | 0.0398879 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.038482 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0380155 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0366047 |
| HLA-E | major histocompatibility complex, class I, E | 0.0365363 |
| RPL37A | ribosomal protein L37a | 0.03642 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0364145 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0361236 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0359263 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0358044 |
| EGFR | epidermal growth factor receptor | 0.0357598 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0355873 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.035213 |
| CTSA | cathepsin A | 0.0351305 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0341959 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0340117 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0337163 |
| RPS3 | ribosomal protein S3 | 0.0336307 |
| LOX | lysyl oxidase | 0.0334353 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0331306 |
| CTTN | cortactin | 0.0322128 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0307476 |
| DUSP6 | dual specificity phosphatase 6 | 0.0305317 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0300321 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0298659 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0296636 |
| HLA-B | major histocompatibility complex, class I, B | 0.0293186 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0293175 |
| ANGPTL4 | angiopoietin-like 4 | 0.029287 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0290625 |
| ATF4 | activating transcription factor 4 | 0.0289462 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0285384 |
| JUN | jun proto-oncogene | 0.028315 |
| FLNB | filamin B, beta | 0.0277558 |
| MCL1 | myeloid cell leukemia 1 | 0.0274851 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0268614 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0266514 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.02659 |
| TGM2 | transglutaminase 2 | 0.0265527 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.026385 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0255283 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0255248 |
| RPS17 | ribosomal protein S17 | 0.0254165 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0253891 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0253458 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0250128 |
| FAM13A | family with sequence similarity 13, member A | 0.0249782 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0247323 |
| MMP12 | matrix metallopeptidase 12 | 0.0244706 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0241412 |
| KIF13A | kinesin family member 13A | 0.0239377 |
| RPS2 | ribosomal protein S2 | 0.0239323 |
| TMEM132D | transmembrane protein 132D | 0.0239203 |
| GDF15 | growth differentiation factor 15 | 0.0238679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.222651 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.133606 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.107302 |
| FRMD4A | FERM domain containing 4A | -0.0968483 |
| VCL | vinculin | -0.087785 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0846486 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0719292 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0664683 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0643741 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0643121 |
| VEGFA | vascular endothelial growth factor A | -0.0603861 |
| SBF2 | SET binding factor 2 | -0.0560924 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0560214 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0543816 |
| MKI67 | marker of proliferation Ki-67 | -0.0537356 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0484362 |
| SPAG9 | sperm associated antigen 9 | -0.0475541 |
| RTN4 | reticulon 4 | -0.0447915 |
| RPL35A | ribosomal protein L35a | -0.044584 |
| CENPF | centromere protein F, 350/400kDa | -0.0442937 |
| MORF4L2 | mortality factor 4 like 2 | -0.0442831 |
| KIF4A | kinesin family member 4A | -0.0440951 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0423502 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0421041 |
| FLNA | filamin A, alpha | -0.0417476 |
| TPM1 | tropomyosin 1 (alpha) | -0.0417203 |
| DST | dystonin | -0.0413582 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0412272 |
| TMSB10 | thymosin beta 10 | -0.0411526 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0410281 |
| TXNRD1 | thioredoxin reductase 1 | -0.0408592 |
| RBM39 | RNA binding motif protein 39 | -0.0407203 |
| GNAS | GNAS complex locus | -0.0406921 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0398375 |
| DEK | DEK proto-oncogene | -0.0391314 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.038875 |
| TPM4 | tropomyosin 4 | -0.0385973 |
| RPS4X | ribosomal protein S4, X-linked | -0.0385168 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0382726 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0381608 |
| RRBP1 | ribosome binding protein 1 | -0.0380297 |
| SMAD3 | SMAD family member 3 | -0.0375047 |
| TAPBP | TAP binding protein (tapasin) | -0.0369451 |
| GOLGA4 | golgin A4 | -0.0368918 |
| YBX1 | Y box binding protein 1 | -0.0362613 |
| MYOF | myoferlin | -0.035051 |
| POTEF | POTE ankyrin domain family, member F | -0.0350446 |
| ANLN | anillin, actin binding protein | -0.034996 |
| MX1 | MX dynamin-like GTPase 1 | -0.0346071 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0338431 |
| DIAPH3 | diaphanous-related formin 3 | -0.0335048 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0332611 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0329182 |
| RPS24 | ribosomal protein S24 | -0.032446 |
| ARF4 | ADP-ribosylation factor 4 | -0.031648 |
| MATR3 | matrin 3 | -0.0315169 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0314613 |
| THBS1 | thrombospondin 1 | -0.0309497 |
| SDC4 | syndecan 4 | -0.0305688 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0304929 |
| TUBB | tubulin, beta class I | -0.030304 |
| CADM1 | cell adhesion molecule 1 | -0.0300354 |
| CLIC4 | chloride intracellular channel 4 | -0.0299702 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0297579 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0297342 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0295018 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0285582 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0285503 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0284599 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0281831 |
| WTAP | Wilms tumor 1 associated protein | -0.027985 |
| CEP95 | centrosomal protein 95kDa | -0.0272718 |
| MIS18BP1 | MIS18 binding protein 1 | -0.027188 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0268101 |
| HDAC8 | histone deacetylase 8 | -0.0267914 |
| CDCP1 | CUB domain containing protein 1 | -0.0266277 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0266045 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0264374 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0260786 |
| RPS20 | ribosomal protein S20 | -0.0258949 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0258764 |
| HLA-C | major histocompatibility complex, class I, C | -0.0258204 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0258076 |
| VCAN | versican | -0.0256666 |
| ACTN1 | actinin, alpha 1 | -0.0255668 |
| TPX2 | TPX2, microtubule-associated | -0.0252995 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0251215 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0251125 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0247729 |
| RPL38 | ribosomal protein L38 | -0.0247245 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0246853 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0245517 |
| RUNX2 | runt-related transcription factor 2 | -0.0244929 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0243579 |
| OSMR | oncostatin M receptor | -0.0243275 |
| CALD1 | caldesmon 1 | -0.0240004 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0239922 |
| FRMD5 | FERM domain containing 5 | -0.0236796 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0236453 |
| MYLK | myosin light chain kinase | -0.0233875 |
