| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.150534 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.107936 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0966485 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0718417 |
| PRELID2 | PRELI domain containing 2 | 0.0637524 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0613805 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0605094 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0565086 |
| FAM13A | family with sequence similarity 13, member A | 0.0551496 |
| KYNU | kynureninase | 0.0521982 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0483307 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0468606 |
| COG6 | component of oligomeric golgi complex 6 | 0.0450751 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0438309 |
| CANX | calnexin | 0.0431637 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.043086 |
| FNIP1 | folliculin interacting protein 1 | 0.0418079 |
| EFNA5 | ephrin-A5 | 0.0395854 |
| GSE1 | Gse1 coiled-coil protein | 0.0393981 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387839 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0377252 |
| IL6 | interleukin 6 | 0.0375042 |
| HLA-A | major histocompatibility complex, class I, A | 0.037055 |
| SEC24D | SEC24 family member D | 0.0345382 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0344333 |
| INTS6 | integrator complex subunit 6 | 0.033679 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0333403 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0332717 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0331714 |
| SP100 | SP100 nuclear antigen | 0.0329559 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0325314 |
| WWOX | WW domain containing oxidoreductase | 0.0325021 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0323414 |
| FOSL1 | FOS-like antigen 1 | 0.0318348 |
| FN1 | fibronectin 1 | 0.0316797 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.031137 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0310906 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0308017 |
| ATXN1 | ataxin 1 | 0.0302808 |
| MCL1 | myeloid cell leukemia 1 | 0.0301778 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0301728 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0290591 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0283591 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0275509 |
| USO1 | USO1 vesicle transport factor | 0.0270808 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0264739 |
| ZNF638 | zinc finger protein 638 | 0.0262348 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.025686 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0253266 |
| GLRX | glutaredoxin (thioltransferase) | 0.0253262 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0251113 |
| PRKCA | protein kinase C, alpha | 0.0250894 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0250807 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0248395 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0248038 |
| YEATS2 | YEATS domain containing 2 | 0.0243298 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0242088 |
| MPZ | myelin protein zero | 0.0241894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0237158 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.023589 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0235874 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0235799 |
| IL6ST | interleukin 6 signal transducer | 0.0235683 |
| ZNF148 | zinc finger protein 148 | 0.0235246 |
| RPL9 | ribosomal protein L9 | 0.0225611 |
| PRKCE | protein kinase C, epsilon | 0.0224789 |
| MYO1E | myosin IE | 0.0222088 |
| SYNJ2 | synaptojanin 2 | 0.0221827 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0221319 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.022125 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0220193 |
| NCOR2 | nuclear receptor corepressor 2 | 0.022001 |
| EGFR | epidermal growth factor receptor | 0.0219728 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0217239 |
| ATXN7 | ataxin 7 | 0.021669 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0216599 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0216012 |
| METTL15 | methyltransferase like 15 | 0.0214562 |
| NRXN3 | neurexin 3 | 0.0211892 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0211892 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0210203 |
| RAD51B | RAD51 paralog B | 0.0209801 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0209402 |
| JAK1 | Janus kinase 1 | 0.0209325 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0208662 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0207647 |
| MSN | moesin | 0.0207352 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0205546 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0205405 |
| STX12 | syntaxin 12 | 0.0205198 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.0205106 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0204863 |
| KIAA1328 | KIAA1328 | 0.0204749 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0203831 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0203193 |
| CMIP | c-Maf inducing protein | 0.0202791 |
| PGM3 | phosphoglucomutase 3 | 0.0202438 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0202289 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0200022 |
| HDAC9 | histone deacetylase 9 | 0.0199177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.22573 |
| TMSB10 | thymosin beta 10 | -0.169696 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150687 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.139641 |
| COL1A2 | collagen, type I, alpha 2 | -0.107742 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0848121 |
| LOX | lysyl oxidase | -0.0727277 |
| HLA-B | major histocompatibility complex, class I, B | -0.0715343 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0686854 |
| RTN4 | reticulon 4 | -0.0681767 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0614107 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0593773 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0559427 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.05325 |
| VIM | vimentin | -0.0517949 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0500653 |
| NDRG1 | N-myc downstream regulated 1 | -0.0497833 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0492628 |
| COL1A1 | collagen, type I, alpha 1 | -0.0477129 |
| CADM1 | cell adhesion molecule 1 | -0.0468788 |
| SETD5 | SET domain containing 5 | -0.0463488 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0450785 |
| HLA-C | major histocompatibility complex, class I, C | -0.0448753 |
| LOXL2 | lysyl oxidase-like 2 | -0.0448141 |
| SPAG9 | sperm associated antigen 9 | -0.0446657 |
| CDK6 | cyclin-dependent kinase 6 | -0.0442873 |
| RRBP1 | ribosome binding protein 1 | -0.0439593 |
| MT1X | metallothionein 1X | -0.0422646 |
| RLF | rearranged L-myc fusion | -0.0408229 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0405998 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.040348 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0402387 |
| SRPK2 | SRSF protein kinase 2 | -0.0393854 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.039126 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0389585 |
| MAP1B | microtubule-associated protein 1B | -0.0381 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0372793 |
| TAPBP | TAP binding protein (tapasin) | -0.0371839 |
| ARRDC3 | arrestin domain containing 3 | -0.0367334 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0352035 |
| CALU | calumenin | -0.0346172 |
| MAP4 | microtubule-associated protein 4 | -0.034444 |
| RPL35A | ribosomal protein L35a | -0.034223 |
| PKM | pyruvate kinase, muscle | -0.0339687 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0334618 |
| RNF145 | ring finger protein 145 | -0.0331443 |
| TPI1 | triosephosphate isomerase 1 | -0.0330966 |
| USP34 | ubiquitin specific peptidase 34 | -0.0330038 |
| MT2A | metallothionein 2A | -0.0329963 |
| RBM25 | RNA binding motif protein 25 | -0.0324299 |
| PTMA | prothymosin, alpha | -0.0323203 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0322708 |
| CLTC | clathrin, heavy chain (Hc) | -0.0322098 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0321854 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0316105 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0315122 |
| TAGLN2 | transgelin 2 | -0.031266 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0311147 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0307141 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0304486 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0303182 |
| CTSB | cathepsin B | -0.0300349 |
| H3-3B | H3.3 histone B | -0.0299827 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0298367 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0297772 |
| CUL3 | cullin 3 | -0.0293972 |
| OGA | O-GlcNAcase | -0.0293771 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0293301 |
| SDC4 | syndecan 4 | -0.029259 |
| LDHA | lactate dehydrogenase A | -0.0287608 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0287272 |
| MYOF | myoferlin | -0.0285727 |
| TPM1 | tropomyosin 1 (alpha) | -0.0284921 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0282727 |
| S100A9 | S100 calcium binding protein A9 | -0.0280742 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0280291 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0278811 |
| NRP1 | neuropilin 1 | -0.0275514 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0274195 |
| KIF1B | kinesin family member 1B | -0.0274013 |
| SYNPO | synaptopodin | -0.0273938 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0273894 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0271097 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0270202 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0268218 |
| SCFD2 | sec1 family domain containing 2 | -0.0268211 |
| UBC | ubiquitin C | -0.0268093 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0266787 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0264001 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0260529 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0259953 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0259731 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0256629 |
| FLOT1 | flotillin 1 | -0.0256138 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0255954 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.025588 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0255455 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | -0.0255119 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0254255 |
| TMEM87A | transmembrane protein 87A | -0.0249984 |
