| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.116654 |
| ASPH | aspartate beta-hydroxylase | 0.114162 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0845105 |
| FAM13A | family with sequence similarity 13, member A | 0.0639844 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0585298 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0549667 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0545064 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0526621 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0512047 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.050629 |
| MCL1 | myeloid cell leukemia 1 | 0.0504796 |
| DUSP6 | dual specificity phosphatase 6 | 0.0496141 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0485343 |
| ENO1 | enolase 1, (alpha) | 0.045029 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0429973 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0417223 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0410231 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0384856 |
| ACTG1 | actin gamma 1 | 0.0366252 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0362449 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0361794 |
| POTEF | POTE ankyrin domain family, member F | 0.035723 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.035033 |
| AREG | amphiregulin | 0.0319014 |
| S100A10 | S100 calcium binding protein A10 | 0.0318134 |
| TXNIP | thioredoxin interacting protein | 0.0316804 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0304693 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0300344 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0293772 |
| JUN | jun proto-oncogene | 0.0291978 |
| EGR1 | early growth response 1 | 0.0290332 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0288136 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0286229 |
| IL6ST | interleukin 6 signal transducer | 0.0284071 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0280882 |
| UBC | ubiquitin C | 0.0279987 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0277981 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0277067 |
| PCBP3 | poly(rC) binding protein 3 | 0.0269661 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0268867 |
| MYOF | myoferlin | 0.0267527 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0266019 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0263292 |
| ARFGEF3 | ARFGEF family member 3 | 0.0260035 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0255061 |
| FAM219A | family with sequence similarity 219, member A | 0.024863 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0247081 |
| RND3 | Rho family GTPase 3 | 0.0235385 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0233982 |
| OXR1 | oxidation resistance 1 | 0.0233091 |
| FLNA | filamin A, alpha | 0.0229881 |
| GOLGB1 | golgin B1 | 0.0226133 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0225817 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0222759 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.022152 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0220041 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0217875 |
| PLIN2 | perilipin 2 | 0.0217342 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0204992 |
| TMF1 | TATA element modulatory factor 1 | 0.0203712 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0203256 |
| SGMS2 | sphingomyelin synthase 2 | 0.0202024 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0199134 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0196921 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0196802 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0192124 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0191432 |
| TGM2 | transglutaminase 2 | 0.0191338 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0191047 |
| IFI44L | interferon-induced protein 44-like | 0.0189347 |
| LOXL2 | lysyl oxidase-like 2 | 0.018874 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0188596 |
| NDRG1 | N-myc downstream regulated 1 | 0.0188559 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0187031 |
| HM13 | histocompatibility (minor) 13 | 0.0185334 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0184957 |
| FOSL1 | FOS-like antigen 1 | 0.0184719 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0183506 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0182938 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0182407 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0178453 |
| GPC6 | glypican 6 | 0.0175812 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0172854 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0172516 |
| RUNX1 | runt-related transcription factor 1 | 0.0171098 |
| NAV2 | neuron navigator 2 | 0.016849 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0167593 |
| PFKP | phosphofructokinase, platelet | 0.0166282 |
| PCBP1 | poly(rC) binding protein 1 | 0.0166247 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0166073 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0165613 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0164835 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.016335 |
| HLA-A | major histocompatibility complex, class I, A | 0.0162841 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0162208 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0159778 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0159653 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0158124 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0157647 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0157375 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.311919 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.229975 |
| NRG1 | neuregulin 1 | -0.198686 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.161244 |
| GLIS3 | GLIS family zinc finger 3 | -0.13963 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.109666 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105946 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.105803 |
| CANX | calnexin | -0.0983155 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0762225 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0657783 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0625974 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0588297 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0548311 |
| TMEM156 | transmembrane protein 156 | -0.0539775 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0527525 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0504893 |
| SYT1 | synaptotagmin I | -0.0501326 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0492128 |
| OSMR | oncostatin M receptor | -0.0489992 |
| ITGA1 | integrin, alpha 1 | -0.0485232 |
| AOPEP | aminopeptidase O (putative) | -0.0476825 |
| FTL | ferritin, light polypeptide | -0.0455712 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0431577 |
| RBM39 | RNA binding motif protein 39 | -0.042904 |
| NRP1 | neuropilin 1 | -0.0428817 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0424895 |
| RUNX2 | runt-related transcription factor 2 | -0.0422627 |
| NTN4 | netrin 4 | -0.0410661 |
| SPAG9 | sperm associated antigen 9 | -0.0398944 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0396323 |
| PKM | pyruvate kinase, muscle | -0.038922 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0384845 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0384731 |
| ARF1 | ADP-ribosylation factor 1 | -0.0381462 |
| H1-0 | H1.0 linker histone | -0.0380409 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0374523 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0373657 |
| TMSB10 | thymosin beta 10 | -0.0371141 |
| RPS20 | ribosomal protein S20 | -0.0370638 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0368766 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.036857 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0368456 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0366542 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0361994 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0358288 |
| RNF213 | ring finger protein 213 | -0.0355064 |
| QKI | QKI, KH domain containing, RNA binding | -0.0355045 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0354529 |
| CALR | calreticulin | -0.0353363 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0353358 |
| DENND5B | DENN/MADD domain containing 5B | -0.0352322 |
| TGFA | transforming growth factor, alpha | -0.0347498 |
| HMGA2 | high mobility group AT-hook 2 | -0.0345228 |
| LOC112694756 | uncharaterized LOC112694756 | -0.034419 |
| TMSB4X | thymosin beta 4, X-linked | -0.0334773 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.033061 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0327254 |
| ENAH | enabled homolog (Drosophila) | -0.0326777 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0324798 |
| RHEB | Ras homolog enriched in brain | -0.0324111 |
| RPS19 | ribosomal protein S19 | -0.0322501 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0322346 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0321921 |
| RLF | rearranged L-myc fusion | -0.0320441 |
| TXNRD1 | thioredoxin reductase 1 | -0.0319577 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0317959 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.031656 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.031541 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.031508 |
| KLHL5 | kelch-like family member 5 | -0.0310385 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0309829 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0303236 |
| RNF145 | ring finger protein 145 | -0.0303094 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0302941 |
| CDC27 | cell division cycle 27 | -0.0300776 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0297098 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0296724 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0296133 |
| TNS3 | tensin 3 | -0.0294932 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0292648 |
| PARD3 | par-3 family cell polarity regulator | -0.02898 |
| ATXN2 | ataxin 2 | -0.028966 |
| ETV6 | ets variant 6 | -0.0288791 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0288094 |
| RPS6 | ribosomal protein S6 | -0.0287059 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0286556 |
| NEK7 | NIMA-related kinase 7 | -0.0285228 |
| AHR | aryl hydrocarbon receptor | -0.0282048 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0277049 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0274607 |
| AEBP2 | AE binding protein 2 | -0.0262808 |
| SRPK2 | SRSF protein kinase 2 | -0.0262358 |
| SMOX | spermine oxidase | -0.0261768 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0260437 |
| HLA-B | major histocompatibility complex, class I, B | -0.0256224 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.025607 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.025601 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0254083 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0253813 |
