| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.189629 |
| FBN1 | fibrillin 1 | 0.0819312 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0744076 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.053303 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0520375 |
| STC1 | stanniocalcin 1 | 0.0500112 |
| CD44 | CD44 molecule (Indian blood group) | 0.0499792 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0499311 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0461443 |
| APP | amyloid beta (A4) precursor protein | 0.0442832 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0421253 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0405893 |
| GPC6 | glypican 6 | 0.039998 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0399866 |
| MT2A | metallothionein 2A | 0.0386369 |
| SEPTIN9 | septin 9 | 0.0379307 |
| COL1A2 | collagen, type I, alpha 2 | 0.0377559 |
| PKM | pyruvate kinase, muscle | 0.0376451 |
| TXNIP | thioredoxin interacting protein | 0.0374585 |
| COL5A2 | collagen, type V, alpha 2 | 0.0374021 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0368329 |
| ATP13A3 | ATPase type 13A3 | 0.0354758 |
| ARRDC3 | arrestin domain containing 3 | 0.0345723 |
| C1D | C1D nuclear receptor corepressor | 0.0341502 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334668 |
| COL3A1 | collagen, type III, alpha 1 | 0.032822 |
| CD99 | CD99 molecule | 0.0314172 |
| SFTPA2 | surfactant protein A2 | 0.0308121 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.030612 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0304726 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0303458 |
| UBC | ubiquitin C | 0.0301208 |
| SDC4 | syndecan 4 | 0.0299272 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0285007 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0284941 |
| B2M | beta-2-microglobulin | 0.0284496 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0283867 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0283125 |
| SQSTM1 | sequestosome 1 | 0.0282415 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0281907 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0278997 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0267889 |
| ACTN4 | actinin, alpha 4 | 0.0260475 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.025621 |
| OPTN | optineurin | 0.0250227 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0247411 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0245352 |
| VEGFA | vascular endothelial growth factor A | 0.0245301 |
| MCL1 | myeloid cell leukemia 1 | 0.0234219 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0227675 |
| NDRG1 | N-myc downstream regulated 1 | 0.0227154 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0217758 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0217043 |
| RTN4 | reticulon 4 | 0.0215498 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0215309 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0214072 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0213073 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0212231 |
| CLU | clusterin | 0.0211746 |
| MYADM | myeloid-associated differentiation marker | 0.0211195 |
| FADS2 | fatty acid desaturase 2 | 0.0210645 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0209756 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0209576 |
| RNF145 | ring finger protein 145 | 0.0207547 |
| VMP1 | vacuole membrane protein 1 | 0.0205653 |
| PCBP2 | poly(rC) binding protein 2 | 0.0204984 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0199256 |
| LAMB1 | laminin, beta 1 | 0.0193927 |
| PRKCSH | protein kinase C substrate 80K-H | 0.019346 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0187424 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0185663 |
| XPO1 | exportin 1 | 0.0184292 |
| CLIC4 | chloride intracellular channel 4 | 0.0182903 |
| HLA-B | major histocompatibility complex, class I, B | 0.0181721 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0179125 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0178122 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0177273 |
| HLA-E | major histocompatibility complex, class I, E | 0.017662 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0175574 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0175322 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.017508 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0174227 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0173283 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0173215 |
| CTSB | cathepsin B | 0.0172653 |
| TGFB1 | transforming growth factor, beta 1 | 0.0172213 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0171079 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0170912 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0170903 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0168985 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.016855 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0168419 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0168313 |
| BRD4 | bromodomain containing 4 | 0.0167913 |
| SET | SET nuclear proto-oncogene | 0.0167879 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0167715 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0166714 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0165433 |
| ZNF207 | zinc finger protein 207 | 0.0164686 |
| MNT | MAX network transcriptional repressor | 0.0164561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.160302 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.143076 |
| CDH13 | cadherin 13 | -0.132511 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114533 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.097578 |
| PODXL | podocalyxin-like | -0.0931873 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0893757 |
| SLC39A11 | solute carrier family 39, member 11 | -0.083805 |
| FN1 | fibronectin 1 | -0.0699576 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0695799 |
| TMSB10 | thymosin beta 10 | -0.0679098 |
| COL5A1 | collagen, type V, alpha 1 | -0.0664239 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0659859 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0641249 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0632299 |
| VIM | vimentin | -0.0573745 |
| CSTB | cystatin B (stefin B) | -0.0564104 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0559941 |
| S100A10 | S100 calcium binding protein A10 | -0.0489721 |
| LOX | lysyl oxidase | -0.0407452 |
| MAP1B | microtubule-associated protein 1B | -0.0402196 |
| AHNAK | AHNAK nucleoprotein | -0.0396217 |
| PRSS23 | protease, serine, 23 | -0.0378769 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0378291 |
| NAV1 | neuron navigator 1 | -0.0377104 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.03608 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.035772 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.03567 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0348293 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.034686 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0332213 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0330531 |
| CALR | calreticulin | -0.0327874 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0327034 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0322037 |
| FSTL1 | follistatin-like 1 | -0.0318403 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0306537 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0292867 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0287018 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0286886 |
| S100A6 | S100 calcium binding protein A6 | -0.0286378 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0268423 |
| DCLK2 | doublecortin-like kinase 2 | -0.0261576 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0260159 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0257039 |
| LRRC17 | leucine rich repeat containing 17 | -0.0255556 |
| EGFR | epidermal growth factor receptor | -0.0254821 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0252729 |
| EFNA5 | ephrin-A5 | -0.0251098 |
| CYTH3 | cytohesin 3 | -0.0244598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0242762 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0241735 |
| CAVIN1 | caveolae associated protein 1 | -0.0241174 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0232465 |
| PLXNA2 | plexin A2 | -0.0229887 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0223172 |
| FRMD4A | FERM domain containing 4A | -0.0222302 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0218327 |
| RIGI | RNA sensor RIG-I | -0.0217318 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0214656 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0211128 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0210533 |
| CEP170 | centrosomal protein 170kDa | -0.0208778 |
| TOX | thymocyte selection-associated high mobility group box | -0.0205868 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0201774 |
| CUX1 | cut-like homeobox 1 | -0.0199701 |
| IL7R | interleukin 7 receptor | -0.0198532 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0197277 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0196939 |
| SEC24D | SEC24 family member D | -0.0190971 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0189729 |
| FMN2 | formin 2 | -0.0187919 |
| ASPH | aspartate beta-hydroxylase | -0.0187386 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0187016 |
| KRT81 | keratin 81, type II | -0.0185559 |
| PGK1 | phosphoglycerate kinase 1 | -0.0183737 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0183223 |
| DENND1A | DENN/MADD domain containing 1A | -0.0178474 |
| TENM3 | teneurin transmembrane protein 3 | -0.0177842 |
| RASAL2 | RAS protein activator like 2 | -0.0177557 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.017554 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0174514 |
| LMNA | lamin A/C | -0.0171972 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0171086 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0170065 |
| MED13L | mediator complex subunit 13-like | -0.0169246 |
| ARF1 | ADP-ribosylation factor 1 | -0.0164565 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0164411 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0160272 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0158389 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0158088 |
| MSI2 | musashi RNA-binding protein 2 | -0.0158044 |
| ANXA1 | annexin A1 | -0.0157513 |
| SPAG9 | sperm associated antigen 9 | -0.015529 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0154816 |
| ANXA2 | annexin A2 | -0.0154461 |
| NUMB | numb homolog (Drosophila) | -0.0154396 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0154395 |
| RAD51B | RAD51 paralog B | -0.015102 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0150643 |
