| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.237567 |
| PEG10 | paternally expressed 10 | 0.136571 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114728 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.103359 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0965066 |
| CANX | calnexin | 0.0947647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0834409 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0815422 |
| VIM | vimentin | 0.0735029 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.072577 |
| NFIB | nuclear factor I/B | 0.0703961 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0670985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.066675 |
| QKI | QKI, KH domain containing, RNA binding | 0.0642254 |
| GSE1 | Gse1 coiled-coil protein | 0.0612869 |
| COL1A2 | collagen, type I, alpha 2 | 0.0612126 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0604584 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.058146 |
| LDHA | lactate dehydrogenase A | 0.0577705 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0559914 |
| MEOX2 | mesenchyme homeobox 2 | 0.0492387 |
| ENO1 | enolase 1, (alpha) | 0.0485705 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0445023 |
| MATR3 | matrin 3 | 0.0433937 |
| MED13L | mediator complex subunit 13-like | 0.0421734 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0396019 |
| OGA | O-GlcNAcase | 0.0395792 |
| KAZN | kazrin, periplakin interacting protein | 0.039278 |
| ZNF292 | zinc finger protein 292 | 0.0389995 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0388298 |
| XPO1 | exportin 1 | 0.0387473 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0377896 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0376808 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0371267 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0371238 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0369852 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0365905 |
| BCOR | BCL6 corepressor | 0.0360845 |
| PCM1 | pericentriolar material 1 | 0.0355868 |
| ITGAV | integrin, alpha V | 0.0348339 |
| APP | amyloid beta (A4) precursor protein | 0.0338434 |
| CALR | calreticulin | 0.0336146 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0330497 |
| YBX1 | Y box binding protein 1 | 0.0329844 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0321959 |
| SEPTIN11 | septin 11 | 0.0320059 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0315228 |
| MGP | matrix Gla protein | 0.0314796 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0308579 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0308309 |
| GOLGA4 | golgin A4 | 0.0308156 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.030768 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0304472 |
| TMSB4X | thymosin beta 4, X-linked | 0.0302229 |
| HOXC10 | homeobox C10 | 0.0299507 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0298955 |
| SFTPA2 | surfactant protein A2 | 0.0297868 |
| VEGFA | vascular endothelial growth factor A | 0.0297238 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.029554 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0295289 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0291464 |
| SET | SET nuclear proto-oncogene | 0.029081 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0288327 |
| PGK1 | phosphoglycerate kinase 1 | 0.02873 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0281763 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0280584 |
| NBEA | neurobeachin | 0.02804 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.02791 |
| PCBP2 | poly(rC) binding protein 2 | 0.0274145 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0269594 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0269484 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0268588 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0265095 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0262291 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0258839 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0256234 |
| PHIP | pleckstrin homology domain interacting protein | 0.0245759 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0243813 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0243357 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0240487 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.023967 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0239663 |
| PRELID2 | PRELI domain containing 2 | 0.0238155 |
| PDGFC | platelet derived growth factor C | 0.0237895 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0237197 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0236129 |
| CNN3 | calponin 3, acidic | 0.0234053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.023387 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0231355 |
| SRPK2 | SRSF protein kinase 2 | 0.0230367 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0228338 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0227283 |
| RPS18 | ribosomal protein S18 | 0.0226579 |
| AHNAK | AHNAK nucleoprotein | 0.0225998 |
| NRDC | nardilysin convertase | 0.0225676 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0224648 |
| UTRN | utrophin | 0.0224565 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0222877 |
| NFIA | nuclear factor I/A | 0.0222407 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0219366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0341661 |
| ACTG1 | actin gamma 1 | -0.0298452 |
| RPL35A | ribosomal protein L35a | -0.0274815 |
| RPL37A | ribosomal protein L37a | -0.0216108 |
| RPL34 | ribosomal protein L34 | -0.0191161 |
| RPL38 | ribosomal protein L38 | -0.0190476 |
| S100A6 | S100 calcium binding protein A6 | -0.0179666 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0166169 |
| NAV1 | neuron navigator 1 | -0.0161598 |
| CDH13 | cadherin 13 | -0.0159944 |
| CD44 | CD44 molecule (Indian blood group) | -0.0159874 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0158544 |
| EFNA5 | ephrin-A5 | -0.0157225 |
| MT2A | metallothionein 2A | -0.0151006 |
| HLA-B | major histocompatibility complex, class I, B | -0.0148739 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0148303 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0145403 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0142926 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0142822 |
| RPS23 | ribosomal protein S23 | -0.0142264 |
| INTS6 | integrator complex subunit 6 | -0.0138251 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0133992 |
| TNRC6B | trinucleotide repeat containing 6B | -0.013138 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0127515 |
| GNAS | GNAS complex locus | -0.012746 |
| FTL | ferritin, light polypeptide | -0.0125732 |
| RPS24 | ribosomal protein S24 | -0.0119835 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0119067 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0117123 |
| HMGA1 | high mobility group AT-hook 1 | -0.0115463 |
| CCND1 | cyclin D1 | -0.011452 |
| SHLD2 | shieldin complex subunit 2 | -0.0111078 |
| MAX | MYC associated factor X | -0.0109904 |
| RPS25 | ribosomal protein S25 | -0.0109087 |
| RPS29 | ribosomal protein S29 | -0.0107679 |
| FHIT | fragile histidine triad | -0.0106696 |
| KYNU | kynureninase | -0.0106417 |
| DTNA | dystrobrevin, alpha | -0.0105258 |
| RPS27 | ribosomal protein S27 | -0.0104155 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0103485 |
| MOSMO | modulator of smoothened | -0.0103285 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0102558 |
| FAM193B | family with sequence similarity 193, member B | -0.0101357 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0100993 |
| EGR1 | early growth response 1 | -0.0100869 |
| FMN1 | formin 1 | -0.00999668 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.00978271 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.00971671 |
| HMGB1 | high mobility group box 1 | -0.00970688 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | -0.00967085 |
| FOXP1 | forkhead box P1 | -0.00963626 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00960748 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00956229 |
| SYNRG | synergin, gamma | -0.00956072 |
| ATXN1 | ataxin 1 | -0.00948905 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00947334 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.00944834 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00943549 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00939564 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.00930233 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00923754 |
| MKI67 | marker of proliferation Ki-67 | -0.00923324 |
| CAPNS1 | calpain, small subunit 1 | -0.00921304 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00919267 |
| AREG | amphiregulin | -0.00918924 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00912248 |
| GOLGB1 | golgin B1 | -0.00910171 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0091016 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00905047 |
| MMP12 | matrix metallopeptidase 12 | -0.00898053 |
| SAP130 | Sin3A-associated protein, 130kDa | -0.0089803 |
| HM13 | histocompatibility (minor) 13 | -0.00897661 |
| COPS2 | COP9 signalosome subunit 2 | -0.00896761 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.00892456 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.00889033 |
| GLIS3 | GLIS family zinc finger 3 | -0.00888709 |
| RPS15 | ribosomal protein S15 | -0.00886971 |
| ENOSF1 | enolase superfamily member 1 | -0.00886938 |
| IER3 | immediate early response 3 | -0.00885658 |
| LRRC23 | leucine rich repeat containing 23 | -0.00881448 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00880709 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | -0.0088016 |
| RUNX1 | runt-related transcription factor 1 | -0.00879623 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00874881 |
| RPL28 | ribosomal protein L28 | -0.00874323 |
| PLIN2 | perilipin 2 | -0.00873585 |
| ZNF432 | zinc finger protein 432 | -0.00869506 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00869155 |
| TJP2 | tight junction protein 2 | -0.00866124 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.00865069 |
| KIF20B | kinesin family member 20B | -0.00864805 |
| DAGLB | diacylglycerol lipase, beta | -0.00864706 |
| ATN1 | atrophin 1 | -0.00861215 |
| RPL8 | ribosomal protein L8 | -0.00857749 |
| KLHL13 | kelch-like family member 13 | -0.00853651 |
| CCDC18 | coiled-coil domain containing 18 | -0.00852212 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00850436 |
| LASP1 | LIM and SH3 protein 1 | -0.00849397 |
| RPL9 | ribosomal protein L9 | -0.00840999 |
| JUN | jun proto-oncogene | -0.00839467 |
