| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.104296 |
| PLEC | plectin | 0.0939695 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0771592 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0693564 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0666693 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0663742 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0658179 |
| SMAD3 | SMAD family member 3 | 0.0590859 |
| SQSTM1 | sequestosome 1 | 0.0532596 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0530668 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0526235 |
| POTEF | POTE ankyrin domain family, member F | 0.052428 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0518198 |
| VCL | vinculin | 0.0517731 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0491903 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0479609 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0442676 |
| PTK2 | protein tyrosine kinase 2 | 0.0441281 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.042669 |
| PCBP2 | poly(rC) binding protein 2 | 0.042215 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383799 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0367375 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0353395 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.035122 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0349018 |
| ASPH | aspartate beta-hydroxylase | 0.0345601 |
| VCAN | versican | 0.0344643 |
| CANX | calnexin | 0.0340688 |
| CAB39 | calcium binding protein 39 | 0.0336931 |
| RTN4 | reticulon 4 | 0.0330386 |
| MYOF | myoferlin | 0.0330315 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0326281 |
| MUC17 | mucin 17, cell surface associated | 0.0324744 |
| TRRAP | transformation/transcription domain-associated protein | 0.0322457 |
| PARD3 | par-3 family cell polarity regulator | 0.032216 |
| ANXA11 | annexin A11 | 0.0321346 |
| CORO1C | coronin, actin binding protein, 1C | 0.0313907 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0313009 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0308067 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0305506 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0303102 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0296576 |
| IPO7 | importin 7 | 0.0295283 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0288663 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0287552 |
| MCL1 | myeloid cell leukemia 1 | 0.0283917 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0282721 |
| MYO6 | myosin VI | 0.0271783 |
| SIK3 | SIK family kinase 3 | 0.0268757 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0268661 |
| ACTN4 | actinin, alpha 4 | 0.0267374 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0262701 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.026079 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.026011 |
| TUFT1 | tuftelin 1 | 0.025967 |
| TOP1 | topoisomerase (DNA) I | 0.0254595 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0254117 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0249226 |
| PTEN | phosphatase and tensin homolog | 0.0245043 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0244866 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0243621 |
| VMP1 | vacuole membrane protein 1 | 0.02433 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0239579 |
| SEPTIN9 | septin 9 | 0.0237092 |
| WWC1 | WW and C2 domain containing 1 | 0.0235384 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0235267 |
| CCNY | cyclin Y | 0.0234171 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0233981 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0233207 |
| RAB10 | RAB10, member RAS oncogene family | 0.0232746 |
| FOXO1 | forkhead box O1 | 0.0230261 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0230121 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0227692 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0226954 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0226535 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0225899 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0225853 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0223316 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0223021 |
| B2M | beta-2-microglobulin | 0.0223014 |
| SFTPA2 | surfactant protein A2 | 0.0222674 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0222442 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0220871 |
| CDHR2 | cadherin-related family member 2 | 0.0219858 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0215787 |
| TNPO1 | transportin 1 | 0.0215411 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0215109 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214799 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0211546 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0211362 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0211217 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0210314 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.020772 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0207345 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0205546 |
| RASAL2 | RAS protein activator like 2 | 0.0204723 |
| USP34 | ubiquitin specific peptidase 34 | 0.0204098 |
| MED13L | mediator complex subunit 13-like | 0.02012 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0194888 |
| HLA-E | major histocompatibility complex, class I, E | 0.0194197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.216227 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.133642 |
| TMSB10 | thymosin beta 10 | -0.105576 |
| NDRG1 | N-myc downstream regulated 1 | -0.0965933 |
| FLNB | filamin B, beta | -0.0819183 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0801141 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0797388 |
| S100A10 | S100 calcium binding protein A10 | -0.0775123 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0676649 |
| LAMA4 | laminin, alpha 4 | -0.066389 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0601608 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0587905 |
| PGK1 | phosphoglycerate kinase 1 | -0.0576057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0567834 |
| VIM | vimentin | -0.0550885 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0527243 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0508484 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0484556 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0476024 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0470885 |
| FAM107B | family with sequence similarity 107, member B | -0.0469748 |
| CSTB | cystatin B (stefin B) | -0.045782 |
| EMP1 | epithelial membrane protein 1 | -0.0442574 |
| PTMA | prothymosin, alpha | -0.043258 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0407387 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0397258 |
| S100A11 | S100 calcium binding protein A11 | -0.0395165 |
| DSG2 | desmoglein 2 | -0.0392493 |
| S100A6 | S100 calcium binding protein A6 | -0.038578 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0380856 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0371919 |
| FAM13A | family with sequence similarity 13, member A | -0.0361547 |
| KLK10 | kallikrein-related peptidase 10 | -0.0332792 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0327126 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0325659 |
| LMO7 | LIM domain 7 | -0.032262 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0309311 |
| GNAS | GNAS complex locus | -0.0288848 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0282533 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0279662 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0276991 |
| RPL12 | ribosomal protein L12 | -0.0276016 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0275178 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0270949 |
| ANXA2 | annexin A2 | -0.0268709 |
| SPAG9 | sperm associated antigen 9 | -0.0268143 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.026316 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0261422 |
| RIOK3 | RIO kinase 3 | -0.0259164 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0252328 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0250094 |
| S100A4 | S100 calcium binding protein A4 | -0.0248479 |
| NBEAL1 | neurobeachin-like 1 | -0.0247263 |
| ANLN | anillin, actin binding protein | -0.0243732 |
| CD2AP | CD2-associated protein | -0.0243282 |
| RPL35A | ribosomal protein L35a | -0.0237848 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0237706 |
| RPS21 | ribosomal protein S21 | -0.0233644 |
| EXOC1 | exocyst complex component 1 | -0.0233546 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0229763 |
| MORF4L2 | mortality factor 4 like 2 | -0.0228928 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.0227665 |
| MXD1 | MAX dimerization protein 1 | -0.0226501 |
| RPL34 | ribosomal protein L34 | -0.0226456 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0224404 |
| SRP54 | signal recognition particle 54kDa | -0.0224175 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0223546 |
| DUSP6 | dual specificity phosphatase 6 | -0.0222613 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0222457 |
| ANXA1 | annexin A1 | -0.0220241 |
| RPL23 | ribosomal protein L23 | -0.0219887 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0217652 |
| SDC4 | syndecan 4 | -0.0217197 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0213478 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -0.0211694 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0210334 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0209712 |
| RPL27A | ribosomal protein L27a | -0.0207137 |
| TPI1 | triosephosphate isomerase 1 | -0.0206441 |
| SEC24A | SEC24 family member A | -0.0205474 |
| AHNAK | AHNAK nucleoprotein | -0.0204778 |
| S100A9 | S100 calcium binding protein A9 | -0.0203984 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0202022 |
| KLF6 | Kruppel-like factor 6 | -0.0201698 |
| INSIG2 | insulin induced gene 2 | -0.0201246 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0199455 |
| KIF13B | kinesin family member 13B | -0.019844 |
| PLEK2 | pleckstrin 2 | -0.0198223 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0196489 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0192476 |
| ENO1 | enolase 1, (alpha) | -0.0188934 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0184949 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0184804 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.018417 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0183869 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0183705 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0183558 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0180294 |
| FERMT1 | fermitin family member 1 | -0.0178282 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0177658 |
