| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.260716 |
| VGF | VGF nerve growth factor inducible | 0.170477 |
| FMN1 | formin 1 | 0.0803159 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0697899 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0680585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0537314 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0482891 |
| APP | amyloid beta (A4) precursor protein | 0.0463279 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0384081 |
| FRMD4A | FERM domain containing 4A | 0.037305 |
| PI15 | peptidase inhibitor 15 | 0.035867 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0349379 |
| ZYX | zyxin | 0.0348253 |
| TNNC1 | troponin C type 1 (slow) | 0.0342266 |
| SFTPA2 | surfactant protein A2 | 0.0339566 |
| ENO1 | enolase 1, (alpha) | 0.0338741 |
| GPC6 | glypican 6 | 0.0338499 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0302786 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0297254 |
| LAMB1 | laminin, beta 1 | 0.0296244 |
| DST | dystonin | 0.0295223 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295108 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0291705 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0283908 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0280486 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0279448 |
| RCAN1 | regulator of calcineurin 1 | 0.0275694 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0274121 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0273739 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.027218 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0267634 |
| SRPK2 | SRSF protein kinase 2 | 0.026702 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0262097 |
| AHR | aryl hydrocarbon receptor | 0.0256662 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.025404 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0253365 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0251645 |
| LDHA | lactate dehydrogenase A | 0.0251602 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0250383 |
| TMEM178B | transmembrane protein 178B | 0.0246371 |
| MTPN | myotrophin | 0.0244741 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0242412 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.023975 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0237921 |
| VMP1 | vacuole membrane protein 1 | 0.0237838 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0233471 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0231457 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0231092 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0230359 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0228685 |
| MCL1 | myeloid cell leukemia 1 | 0.0222758 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.02222 |
| PDE10A | phosphodiesterase 10A | 0.0219846 |
| PLEC | plectin | 0.0212793 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0210105 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0209598 |
| SEM1 | SEM1 26S proteasome subunit | 0.0201522 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0200763 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0200635 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0199218 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0196208 |
| ACTN1 | actinin, alpha 1 | 0.0195697 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0195274 |
| AHNAK | AHNAK nucleoprotein | 0.0194968 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0193023 |
| CDH19 | cadherin 19, type 2 | 0.0189441 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0188774 |
| CLIC4 | chloride intracellular channel 4 | 0.0185798 |
| PGK1 | phosphoglycerate kinase 1 | 0.0185421 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0185095 |
| COPA | coatomer protein complex, subunit alpha | 0.018472 |
| IL6ST | interleukin 6 signal transducer | 0.0182372 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0176313 |
| A2M | alpha-2-macroglobulin | 0.0173775 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0173662 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0172475 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0172431 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.0171411 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0170291 |
| ACTN4 | actinin, alpha 4 | 0.0170105 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0169734 |
| MRTFA | myocardin related transcription factor A | 0.0168811 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.016856 |
| GAS7 | growth arrest-specific 7 | 0.016705 |
| CALU | calumenin | 0.0166688 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0164525 |
| PKM | pyruvate kinase, muscle | 0.0161917 |
| ARRDC3 | arrestin domain containing 3 | 0.0161883 |
| CANX | calnexin | 0.0161658 |
| VCL | vinculin | 0.0160083 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0159706 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0159279 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0158863 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0158858 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0158498 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0158348 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.015526 |
| TAGLN2 | transgelin 2 | 0.0154208 |
| MT2A | metallothionein 2A | 0.01539 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.0153224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128513 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0968216 |
| NLGN1 | neuroligin 1 | -0.0640059 |
| FMNL2 | formin-like 2 | -0.0601742 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0490522 |
| TMSB10 | thymosin beta 10 | -0.0486309 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0472589 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0468563 |
| NDRG1 | N-myc downstream regulated 1 | -0.0449911 |
| S100A6 | S100 calcium binding protein A6 | -0.0416264 |
| OXR1 | oxidation resistance 1 | -0.0364566 |
| SCFD2 | sec1 family domain containing 2 | -0.0356471 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0356354 |
| HLA-B | major histocompatibility complex, class I, B | -0.0342206 |
| PTK2 | protein tyrosine kinase 2 | -0.0338558 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0335601 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0329099 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0313951 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0276849 |
| ZNF704 | zinc finger protein 704 | -0.0273829 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0265042 |
| PHF21A | PHD finger protein 21A | -0.0256165 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0254704 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0250395 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0248987 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0248749 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.023928 |
| PRELID2 | PRELI domain containing 2 | -0.0230726 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0222942 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0216171 |
| RAD51B | RAD51 paralog B | -0.0213431 |
| NPR2 | natriuretic peptide receptor 2 | -0.0213298 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0205115 |
| RPL35A | ribosomal protein L35a | -0.0205045 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0198679 |
| CTTNBP2 | cortactin binding protein 2 | -0.0192619 |
| PARVB | parvin, beta | -0.0188882 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0186632 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0182474 |
| RCOR1 | REST corepressor 1 | -0.0178916 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0178504 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0175799 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0172759 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0171756 |
| ADM | adrenomedullin | -0.0170076 |
| TRIM2 | tripartite motif containing 2 | -0.0169836 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.01696 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0168728 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0167171 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0164503 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0162787 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0162593 |
| CUX1 | cut-like homeobox 1 | -0.0162275 |
| EXOC4 | exocyst complex component 4 | -0.0161758 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.01611 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0159682 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0158742 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0157952 |
| PYGB | phosphorylase, glycogen; brain | -0.0157886 |
| CABIN1 | calcineurin binding protein 1 | -0.0157562 |
| FLNB | filamin B, beta | -0.0155737 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0155409 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0154569 |
| ARFGEF3 | ARFGEF family member 3 | -0.015394 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.015327 |
| RPS8 | ribosomal protein S8 | -0.0152732 |
| RNF24 | ring finger protein 24 | -0.0152502 |
| RPL34 | ribosomal protein L34 | -0.0152251 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0150884 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.015051 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0149835 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0149511 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0146962 |
| FBXO11 | F-box protein 11 | -0.014504 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0138742 |
| ANO10 | anoctamin 10 | -0.0138509 |
| CTSD | cathepsin D | -0.0138241 |
| PTMA | prothymosin, alpha | -0.0138148 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0137878 |
| CD109 | CD109 molecule | -0.0136906 |
| RPS24 | ribosomal protein S24 | -0.0135233 |
| GDF15 | growth differentiation factor 15 | -0.0133789 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0133146 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.013277 |
| RPL28 | ribosomal protein L28 | -0.0132 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0131308 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0131258 |
| SETD5 | SET domain containing 5 | -0.0129035 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0128028 |
| CENPF | centromere protein F, 350/400kDa | -0.0125702 |
| SCFD1 | sec1 family domain containing 1 | -0.0124688 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0123476 |
| FTL | ferritin, light polypeptide | -0.0122821 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0121979 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0120578 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0118675 |
| RRBP1 | ribosome binding protein 1 | -0.0117685 |
| TBCA | tubulin folding cofactor A | -0.0117084 |
| MEIS2 | Meis homeobox 2 | -0.0116693 |
| CERT1 | ceramide transporter 1 | -0.0116476 |
