| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0904024 |
| TGM2 | transglutaminase 2 | 0.0878809 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0795299 |
| PKM | pyruvate kinase, muscle | 0.0745341 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0717468 |
| POTEF | POTE ankyrin domain family, member F | 0.0700482 |
| SMAD3 | SMAD family member 3 | 0.0628072 |
| EFNA5 | ephrin-A5 | 0.0607123 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0582165 |
| MCL1 | myeloid cell leukemia 1 | 0.0570356 |
| APP | amyloid beta (A4) precursor protein | 0.0532835 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0523535 |
| DOCK5 | dedicator of cytokinesis 5 | 0.049219 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0480708 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0477891 |
| ASPH | aspartate beta-hydroxylase | 0.0461128 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0458379 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0458321 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0450533 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0450159 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0412786 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0404125 |
| RAD51B | RAD51 paralog B | 0.0395276 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0390456 |
| NRG3 | neuregulin 3 | 0.0383302 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0378584 |
| B2M | beta-2-microglobulin | 0.0362301 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.035464 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0338451 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0335328 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330664 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0329825 |
| EGR1 | early growth response 1 | 0.0323703 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0318085 |
| MX1 | MX dynamin-like GTPase 1 | 0.0301825 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0297459 |
| KRT19 | keratin 19, type I | 0.0293314 |
| TPM3 | tropomyosin 3 | 0.0292288 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0289719 |
| ITGA6 | integrin, alpha 6 | 0.028963 |
| CDCP1 | CUB domain containing protein 1 | 0.0289386 |
| TXNRD1 | thioredoxin reductase 1 | 0.0285739 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0284639 |
| ATXN1 | ataxin 1 | 0.0283465 |
| PRELID2 | PRELI domain containing 2 | 0.0281679 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0281166 |
| EHBP1 | EH domain binding protein 1 | 0.0279356 |
| PLEC | plectin | 0.0276878 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0276435 |
| VEGFA | vascular endothelial growth factor A | 0.0268175 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0262878 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0262543 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0260153 |
| C3 | complement component 3 | 0.0256419 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0255608 |
| MUC4 | mucin 4, cell surface associated | 0.025473 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0254086 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0249262 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0249023 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0246407 |
| KYNU | kynureninase | 0.0245432 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0243051 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0241578 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0239906 |
| NDRG1 | N-myc downstream regulated 1 | 0.0236126 |
| TAPBP | TAP binding protein (tapasin) | 0.0233761 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0231993 |
| HDAC9 | histone deacetylase 9 | 0.0230492 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0229287 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0228967 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0228754 |
| MUC16 | mucin 16, cell surface associated | 0.0223527 |
| CP | ceruloplasmin (ferroxidase) | 0.0209369 |
| SKIL | SKI-like proto-oncogene | 0.0208672 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0206133 |
| FOSL1 | FOS-like antigen 1 | 0.0205182 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0204432 |
| JUP | junction plakoglobin | 0.0199906 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0199005 |
| SEPTIN9 | septin 9 | 0.0198812 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0198291 |
| CMIP | c-Maf inducing protein | 0.0196404 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0194825 |
| EXOC4 | exocyst complex component 4 | 0.0193791 |
| ACTN4 | actinin, alpha 4 | 0.0193126 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0190216 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0188445 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0188356 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0187565 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0185997 |
| NOTCH2 | notch 2 | 0.0184108 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0183857 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0182654 |
| ANXA4 | annexin A4 | 0.018218 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0181737 |
| HDGF | hepatoma-derived growth factor | 0.0179285 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0178949 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0178938 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0177209 |
| PROM1 | prominin 1 | 0.0176988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.197674 |
| LAMB3 | laminin, beta 3 | -0.170011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155861 |
| MMP7 | matrix metallopeptidase 7 | -0.151939 |
| TMSB10 | thymosin beta 10 | -0.114497 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0996819 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0853234 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0832084 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0791296 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0706888 |
| MT2A | metallothionein 2A | -0.0684228 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0666882 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0641464 |
| OGA | O-GlcNAcase | -0.0602562 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0594647 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0587928 |
| LMO7 | LIM domain 7 | -0.0585421 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0557314 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.055672 |
| DTNA | dystrobrevin, alpha | -0.0542228 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0533278 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0512257 |
| SPAG9 | sperm associated antigen 9 | -0.0505424 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0505146 |
| RBM39 | RNA binding motif protein 39 | -0.0501451 |
| RRBP1 | ribosome binding protein 1 | -0.0491544 |
| H1-0 | H1.0 linker histone | -0.0479096 |
| ANXA2 | annexin A2 | -0.0438485 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0425485 |
| S100A6 | S100 calcium binding protein A6 | -0.0425002 |
| SRP54 | signal recognition particle 54kDa | -0.042307 |
| FTL | ferritin, light polypeptide | -0.0413529 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0393193 |
| SYNRG | synergin, gamma | -0.0376677 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0369403 |
| KLF6 | Kruppel-like factor 6 | -0.036845 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0367015 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0361805 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0358418 |
| ANXA1 | annexin A1 | -0.035504 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.035494 |
| GNAS | GNAS complex locus | -0.0351812 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.034898 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0348205 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0345738 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0345349 |
| CD2AP | CD2-associated protein | -0.0338635 |
| PTMA | prothymosin, alpha | -0.0338199 |
| RIOK3 | RIO kinase 3 | -0.0332718 |
| HLA-B | major histocompatibility complex, class I, B | -0.0331505 |
| MT1X | metallothionein 1X | -0.0327359 |
| DSG2 | desmoglein 2 | -0.0327126 |
| ATP11B | ATPase, class VI, type 11B | -0.0326363 |
| S100A10 | S100 calcium binding protein A10 | -0.0322973 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0322811 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0322424 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0319066 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.031228 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0305262 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0304551 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0302842 |
| TMEM263 | transmembrane protein 263 | -0.0300985 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0300313 |
| RPL35A | ribosomal protein L35a | -0.0299608 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0297409 |
| FNBP1L | formin binding protein 1-like | -0.0295722 |
| LASP1 | LIM and SH3 protein 1 | -0.029338 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0292361 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0286028 |
| AHNAK | AHNAK nucleoprotein | -0.0285988 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0285461 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0283111 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0273179 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0272158 |
| GOLGA4 | golgin A4 | -0.0271156 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0270792 |
| SERF2 | small EDRK-rich factor 2 | -0.0270499 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0268332 |
| CSTB | cystatin B (stefin B) | -0.0264544 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0260936 |
| MCU | mitochondrial calcium uniporter | -0.0259425 |
| ZNF292 | zinc finger protein 292 | -0.0258891 |
| CALR | calreticulin | -0.0257233 |
| ACTG1 | actin gamma 1 | -0.0256768 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0254825 |
| SP100 | SP100 nuclear antigen | -0.025123 |
| CLINT1 | clathrin interactor 1 | -0.0250558 |
| EDN1 | endothelin 1 | -0.0242543 |
| MORF4L2 | mortality factor 4 like 2 | -0.0239694 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.023748 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0236054 |
| RPS21 | ribosomal protein S21 | -0.0234674 |
| RPL37A | ribosomal protein L37a | -0.0234531 |
| YME1L1 | YME1-like 1 ATPase | -0.0234393 |
| RPL34 | ribosomal protein L34 | -0.0232992 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0232473 |
| HPCAL1 | hippocalcin-like 1 | -0.0228979 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0226741 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0226437 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0225478 |
