| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0517661 |
| VCL | vinculin | 0.0467898 |
| LPIN1 | lipin 1 | 0.0438658 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0415339 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0413307 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0386379 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0375159 |
| OGA | O-GlcNAcase | 0.0366553 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0330835 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0323422 |
| HMGB2 | high mobility group box 2 | 0.0289584 |
| CANX | calnexin | 0.0282545 |
| APP | amyloid beta (A4) precursor protein | 0.0281201 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0280869 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.027268 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0264721 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0258142 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0257142 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0249727 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0245897 |
| VGF | VGF nerve growth factor inducible | 0.0244907 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241884 |
| CCNL1 | cyclin L1 | 0.023951 |
| AUTS2 | autism susceptibility candidate 2 | 0.0239273 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0229943 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0225067 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0223853 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0221002 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0218713 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0216289 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0215801 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0211147 |
| MCL1 | myeloid cell leukemia 1 | 0.0210031 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0207537 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0206091 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0203155 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0202887 |
| PLPP1 | phospholipid phosphatase 1 | 0.020239 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0198973 |
| STK38L | serine/threonine kinase 38 like | 0.0194647 |
| TPM4 | tropomyosin 4 | 0.0192396 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.019115 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0189457 |
| MYO9A | myosin IXA | 0.0188731 |
| YTHDC1 | YTH domain containing 1 | 0.018706 |
| SEPTIN2 | septin 2 | 0.0184676 |
| AHNAK | AHNAK nucleoprotein | 0.0184252 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.0183922 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0178904 |
| APTX | aprataxin | 0.0178206 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0174993 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.017391 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0171222 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0165835 |
| TNPO1 | transportin 1 | 0.0164481 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0163978 |
| COL3A1 | collagen, type III, alpha 1 | 0.0163235 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0162768 |
| SGMS1 | sphingomyelin synthase 1 | 0.0161672 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0160489 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0159051 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0159003 |
| CASC3 | cancer susceptibility candidate 3 | 0.0158856 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0157988 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0157572 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0157288 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0156717 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0153794 |
| XPO1 | exportin 1 | 0.0151966 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0151549 |
| CCDC47 | coiled-coil domain containing 47 | 0.0149427 |
| CALU | calumenin | 0.0149106 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0148734 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0148346 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0148204 |
| RIOK3 | RIO kinase 3 | 0.014745 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0147078 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0146717 |
| FERMT2 | fermitin family member 2 | 0.0145946 |
| PHF3 | PHD finger protein 3 | 0.0143879 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0143807 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.014307 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0142967 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0142522 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0140906 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.013981 |
| HSPA8 | heat shock 70kDa protein 8 | 0.013965 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0138398 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0136606 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0135512 |
| SLMAP | sarcolemma associated protein | 0.0135393 |
| CD164 | CD164 molecule, sialomucin | 0.0134225 |
| CFDP1 | craniofacial development protein 1 | 0.0133811 |
| HYOU1 | hypoxia up-regulated 1 | 0.0133475 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0132829 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0132168 |
| RPS18 | ribosomal protein S18 | 0.0131418 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0130671 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0130577 |
| FNIP1 | folliculin interacting protein 1 | 0.0129931 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.308309 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19204 |
| VIM | vimentin | -0.0766598 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.068436 |
| RPL23 | ribosomal protein L23 | -0.0667876 |
| RPS6 | ribosomal protein S6 | -0.0601049 |
| TMSB10 | thymosin beta 10 | -0.0547343 |
| RPL19 | ribosomal protein L19 | -0.0545213 |
| COL1A1 | collagen, type I, alpha 1 | -0.0485099 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0462021 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0451623 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0429701 |
| ACTG1 | actin gamma 1 | -0.0428305 |
| GNAS | GNAS complex locus | -0.0411384 |
| RPL35A | ribosomal protein L35a | -0.0396268 |
| CRH | corticotropin releasing hormone | -0.039549 |
| LSAMP | limbic system-associated membrane protein | -0.0394787 |
| MEIS2 | Meis homeobox 2 | -0.0394272 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0392701 |
| RPL37A | ribosomal protein L37a | -0.038109 |
| TBX2 | T-box 2 | -0.0374599 |
| RPLP1 | ribosomal protein, large, P1 | -0.0373805 |
| BPTF | bromodomain PHD finger transcription factor | -0.0365194 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.035647 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0324848 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0323 |
| NRG1 | neuregulin 1 | -0.0315146 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0310824 |
| PTMA | prothymosin, alpha | -0.030262 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0293846 |
| SYT1 | synaptotagmin I | -0.029076 |
| KLHL13 | kelch-like family member 13 | -0.0288372 |
| H3-3B | H3.3 histone B | -0.028549 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0282689 |
| B2M | beta-2-microglobulin | -0.0281929 |
| RPL38 | ribosomal protein L38 | -0.0277751 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0274013 |
| RPL7A | ribosomal protein L7a | -0.0272808 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0271287 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0266284 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0255093 |
| S100A9 | S100 calcium binding protein A9 | -0.0253596 |
| FNBP1 | formin binding protein 1 | -0.0253304 |
| RPS24 | ribosomal protein S24 | -0.0252681 |
| RPS25 | ribosomal protein S25 | -0.0251218 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0249995 |
| RPL13A | ribosomal protein L13a | -0.024983 |
| DNM3 | dynamin 3 | -0.0249303 |
| CALD1 | caldesmon 1 | -0.0245958 |
| RPL27 | ribosomal protein L27 | -0.0244841 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0244767 |
| MEF2A | myocyte enhancer factor 2A | -0.0242104 |
| NRP1 | neuropilin 1 | -0.0237419 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0232464 |
| MAP1B | microtubule-associated protein 1B | -0.0230667 |
| ZNF804A | zinc finger protein 804A | -0.0230166 |
| RPS19 | ribosomal protein S19 | -0.0228677 |
| GATA3 | GATA binding protein 3 | -0.0224924 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0223268 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.022216 |
| RPS21 | ribosomal protein S21 | -0.0215674 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0215567 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0211061 |
| S100A6 | S100 calcium binding protein A6 | -0.0210389 |
| RPL34 | ribosomal protein L34 | -0.0208872 |
| TPI1 | triosephosphate isomerase 1 | -0.0207477 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0206839 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0206181 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0205985 |
| RPL37 | ribosomal protein L37 | -0.020563 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0201619 |
| RPLP0 | ribosomal protein, large, P0 | -0.0201464 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0200486 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0200392 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0199727 |
| PCDH9 | protocadherin 9 | -0.019831 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.019826 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0197367 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0196705 |
| RPL26 | ribosomal protein L26 | -0.0196644 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0194598 |
| MX2 | MX dynamin-like GTPase 2 | -0.019417 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0192912 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0192619 |
| RPS16 | ribosomal protein S16 | -0.0189321 |
| RPS14 | ribosomal protein S14 | -0.0186686 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0184567 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0184132 |
| RPL28 | ribosomal protein L28 | -0.0183113 |
| FBXO11 | F-box protein 11 | -0.0182721 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0182021 |
| SBF2 | SET binding factor 2 | -0.0179979 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0179954 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0179935 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0179036 |
| IER3 | immediate early response 3 | -0.0178194 |
| RPLP2 | ribosomal protein, large, P2 | -0.0177498 |
| RPS29 | ribosomal protein S29 | -0.0175347 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0175112 |
| SCG2 | secretogranin II | -0.0174684 |
