| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | 0.155849 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.144946 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.133788 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.11763 |
| MX1 | MX dynamin-like GTPase 1 | 0.106902 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.101215 |
| RIGI | RNA sensor RIG-I | 0.0954233 |
| LYZ | lysozyme | 0.0895695 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0864165 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0782796 |
| SP100 | SP100 nuclear antigen | 0.0773378 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0752777 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0747378 |
| MX2 | MX dynamin-like GTPase 2 | 0.0747207 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0729848 |
| VCL | vinculin | 0.0703585 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0701018 |
| EPHB2 | EPH receptor B2 | 0.0681855 |
| LCN2 | lipocalin 2 | 0.0677225 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0655119 |
| LMO7 | LIM domain 7 | 0.0641164 |
| ANXA2 | annexin A2 | 0.0609987 |
| INTS6 | integrator complex subunit 6 | 0.0552383 |
| EGR1 | early growth response 1 | 0.0551467 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0540584 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0506606 |
| ATP11A | ATPase, class VI, type 11A | 0.0503879 |
| SDC4 | syndecan 4 | 0.0459708 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0451027 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.044781 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0444328 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0435099 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0428415 |
| XAF1 | XIAP associated factor 1 | 0.0425504 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0416917 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.040482 |
| TJP1 | tight junction protein 1 | 0.0399826 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0398498 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0398156 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0395142 |
| AREG | amphiregulin | 0.0388209 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.038813 |
| AHNAK | AHNAK nucleoprotein | 0.0377369 |
| PLSCR1 | phospholipid scramblase 1 | 0.0375177 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0374424 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0374143 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0371526 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0367245 |
| PLSCR2 | phospholipid scramblase 2 | 0.0366035 |
| NPSR1 | neuropeptide S receptor 1 | 0.036451 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0364504 |
| SQSTM1 | sequestosome 1 | 0.0363022 |
| HLA-B | major histocompatibility complex, class I, B | 0.0360807 |
| MCL1 | myeloid cell leukemia 1 | 0.0357313 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0356959 |
| LAMA4 | laminin, alpha 4 | 0.0355357 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0353637 |
| STK24 | serine/threonine kinase 24 | 0.0352988 |
| MSI2 | musashi RNA-binding protein 2 | 0.0349819 |
| ITGA6 | integrin, alpha 6 | 0.0337198 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0331087 |
| APP | amyloid beta (A4) precursor protein | 0.0330923 |
| ACTN4 | actinin, alpha 4 | 0.0330295 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0317417 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0316097 |
| KYNU | kynureninase | 0.0313143 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0311689 |
| SERINC5 | serine incorporator 5 | 0.0307247 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0305266 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0303971 |
| SPATA13 | spermatogenesis associated 13 | 0.0297835 |
| ETV6 | ets variant 6 | 0.0296282 |
| ERBIN | erbb2 interacting protein | 0.029528 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0291031 |
| TRIM25 | tripartite motif containing 25 | 0.028993 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0289753 |
| ACTG1 | actin gamma 1 | 0.0289612 |
| FHIT | fragile histidine triad | 0.0285255 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0284546 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0279235 |
| LAP3 | leucine aminopeptidase 3 | 0.0277981 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0276351 |
| PMP22 | peripheral myelin protein 22 | 0.0276107 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0272036 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0271127 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0271036 |
| TMC5 | transmembrane channel-like 5 | 0.0269204 |
| MLPH | melanophilin | 0.0268678 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0268385 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0266505 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0262331 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.026128 |
| JUN | jun proto-oncogene | 0.0260786 |
| MYO1E | myosin IE | 0.0260165 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0257025 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0252249 |
| TTC39B | tetratricopeptide repeat domain 39B | 0.024896 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0247362 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0246475 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0246105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.132139 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.077576 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0744453 |
| B2M | beta-2-microglobulin | -0.0729041 |
| NDRG1 | N-myc downstream regulated 1 | -0.0586204 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0498445 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0491648 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0490665 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0482334 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0453254 |
| GOLGA4 | golgin A4 | -0.0425014 |
| GOLGB1 | golgin B1 | -0.0424585 |
| TXNIP | thioredoxin interacting protein | -0.0415646 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0410295 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0405327 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0374806 |
| COG6 | component of oligomeric golgi complex 6 | -0.0373016 |
| MT2A | metallothionein 2A | -0.0371614 |
| SEC24D | SEC24 family member D | -0.0367406 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.036364 |
| RNF149 | ring finger protein 149 | -0.0361434 |
| CALR | calreticulin | -0.0359426 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0344129 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0332037 |
| SUCO | SUN domain containing ossification factor | -0.0330732 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0330233 |
| SBF2 | SET binding factor 2 | -0.0329972 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0326813 |
| AHI1 | Abelson helper integration site 1 | -0.0321999 |
| RNF43 | ring finger protein 43 | -0.0320687 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0320363 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0314266 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0310876 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0306609 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.030411 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0296157 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0291426 |
| RBM25 | RNA binding motif protein 25 | -0.0285071 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0284742 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0283953 |
| IFNGR1 | interferon gamma receptor 1 | -0.0281248 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0278942 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0277893 |
| DSTN | destrin (actin depolymerizing factor) | -0.0276304 |
| RBM39 | RNA binding motif protein 39 | -0.0276102 |
| EXOC1 | exocyst complex component 1 | -0.0274007 |
| PTEN | phosphatase and tensin homolog | -0.0271946 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.027111 |
| HELZ | helicase with zinc finger | -0.0270292 |
| CLTC | clathrin, heavy chain (Hc) | -0.0266375 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.026597 |
| USPL1 | ubiquitin specific peptidase like 1 | -0.0264921 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0262991 |
| USP3 | ubiquitin specific peptidase 3 | -0.0262185 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0260333 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.025903 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0257326 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0256764 |
| SSR1 | signal sequence receptor, alpha | -0.0254578 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0252844 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0252213 |
| NKTR | natural killer cell triggering receptor | -0.0249289 |
| CEP350 | centrosomal protein 350kDa | -0.0249 |
| OGA | O-GlcNAcase | -0.0248761 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0248636 |
| AGR2 | anterior gradient 2 | -0.0248201 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0246875 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.024122 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0241067 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0239908 |
| NUCB2 | nucleobindin 2 | -0.0239535 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0239392 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0236336 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.023632 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0234381 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0234346 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.023428 |
| SCFD1 | sec1 family domain containing 1 | -0.0233505 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0232972 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0230163 |
| ABHD2 | abhydrolase domain containing 2 | -0.022765 |
| TMF1 | TATA element modulatory factor 1 | -0.0225801 |
| ANXA1 | annexin A1 | -0.0221928 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0221821 |
| MORF4L2 | mortality factor 4 like 2 | -0.0219574 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.021749 |
| RPS6 | ribosomal protein S6 | -0.0216557 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0216351 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0215965 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0214141 |
| AFF1 | AF4/FMR2 family, member 1 | -0.02134 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0213112 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0210359 |
| TMEM87A | transmembrane protein 87A | -0.0208608 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0207648 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0206839 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0206568 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | -0.0205726 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0203251 |
| THOC2 | THO complex 2 | -0.020041 |
