| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KYNU | kynureninase | 0.0594256 |
| PLEC | plectin | 0.0487747 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0442936 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0437231 |
| CANX | calnexin | 0.0423156 |
| APP | amyloid beta (A4) precursor protein | 0.0378336 |
| CALR | calreticulin | 0.0342692 |
| FAM20C | family with sequence similarity 20, member C | 0.0340514 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0333503 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0330294 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0305709 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0286064 |
| PKM | pyruvate kinase, muscle | 0.0281042 |
| SEPTIN9 | septin 9 | 0.0279914 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0274923 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274367 |
| MCL1 | myeloid cell leukemia 1 | 0.0252749 |
| VEGFA | vascular endothelial growth factor A | 0.0245006 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0237012 |
| INTS6 | integrator complex subunit 6 | 0.0228596 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0226889 |
| SDC4 | syndecan 4 | 0.0226277 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0225908 |
| CCPG1 | cell cycle progression 1 | 0.022338 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0219321 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0216085 |
| RPL37A | ribosomal protein L37a | 0.0213507 |
| DIAPH2 | diaphanous-related formin 2 | 0.0211353 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0209217 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0207346 |
| HLA-B | major histocompatibility complex, class I, B | 0.0206636 |
| INHBA | inhibin, beta A | 0.0206483 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0201282 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0198149 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0195623 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0194689 |
| RPL31 | ribosomal protein L31 | 0.019393 |
| GOLGA3 | golgin A3 | 0.0184551 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0184277 |
| THBS1 | thrombospondin 1 | 0.0180192 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0179093 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.017869 |
| CHMP5 | charged multivesicular body protein 5 | 0.0176909 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0176347 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0173205 |
| VGF | VGF nerve growth factor inducible | 0.0172989 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0169557 |
| RPL19 | ribosomal protein L19 | 0.0165192 |
| STC2 | stanniocalcin 2 | 0.0164022 |
| CDH13 | cadherin 13 | 0.0163044 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0161356 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0159985 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0158618 |
| LDHA | lactate dehydrogenase A | 0.0157767 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0157399 |
| RAI14 | retinoic acid induced 14 | 0.0156947 |
| SMAD3 | SMAD family member 3 | 0.0155993 |
| CDV3 | CDV3 homolog (mouse) | 0.0155516 |
| FLNA | filamin A, alpha | 0.0151006 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.01486 |
| KIF16B | kinesin family member 16B | 0.0146682 |
| ARRDC3 | arrestin domain containing 3 | 0.0146008 |
| VMP1 | vacuole membrane protein 1 | 0.0145097 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0144653 |
| DGKI | diacylglycerol kinase, iota | 0.0141845 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0141639 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0140674 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.014036 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0140084 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0139305 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0139174 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0138239 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.013809 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0137476 |
| FAT1 | FAT atypical cadherin 1 | 0.0137132 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0136667 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0135268 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0134187 |
| KLF10 | Kruppel-like factor 10 | 0.0133675 |
| C1S | complement component 1, s subcomponent | 0.0132702 |
| MB21D2 | Mab-21 domain containing 2 | 0.0132535 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.013133 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0131118 |
| EGR1 | early growth response 1 | 0.0130802 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0129398 |
| MLEC | malectin | 0.0128975 |
| ECE1 | endothelin converting enzyme 1 | 0.0128874 |
| CCDC6 | coiled-coil domain containing 6 | 0.0128689 |
| HDAC4 | histone deacetylase 4 | 0.0127039 |
| PRELID2 | PRELI domain containing 2 | 0.0125549 |
| RPL3 | ribosomal protein L3 | 0.0125438 |
| TOP1 | topoisomerase (DNA) I | 0.0124802 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0124699 |
| GTPBP2 | GTP binding protein 2 | 0.0122455 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0121996 |
| IER3 | immediate early response 3 | 0.012109 |
| PDCD6 | programmed cell death 6 | 0.0120962 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0120662 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0119825 |
| GYPC | glycophorin C (Gerbich blood group) | 0.0119794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259311 |
| TMSB10 | thymosin beta 10 | -0.0953463 |
| MT2A | metallothionein 2A | -0.0827268 |
| COL6A3 | collagen, type VI, alpha 3 | -0.082192 |
| VIM | vimentin | -0.0806918 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0719847 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0581893 |
| MAP1B | microtubule-associated protein 1B | -0.0509958 |
| MT1X | metallothionein 1X | -0.0469415 |
| NDRG1 | N-myc downstream regulated 1 | -0.0466732 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0429207 |
| CD44 | CD44 molecule (Indian blood group) | -0.0429042 |
| ANKRD11 | ankyrin repeat domain 11 | -0.042564 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0410948 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0389977 |
| FN1 | fibronectin 1 | -0.0387479 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0367297 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0365272 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0359484 |
| SBF2 | SET binding factor 2 | -0.0357936 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0355262 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0352001 |
| EGFR | epidermal growth factor receptor | -0.0342926 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0341275 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0336049 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.033237 |
| CDK13 | cyclin-dependent kinase 13 | -0.032349 |
| EHBP1 | EH domain binding protein 1 | -0.0323015 |
| DST | dystonin | -0.0322817 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0321456 |
| GOLGA4 | golgin A4 | -0.0320272 |
| GNAS | GNAS complex locus | -0.0319977 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0318312 |
| STK17A | serine/threonine kinase 17a | -0.0314822 |
| CALD1 | caldesmon 1 | -0.0306507 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299006 |
| NF1 | neurofibromin 1 | -0.0297188 |
| RPS6 | ribosomal protein S6 | -0.0296062 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0284284 |
| RPLP2 | ribosomal protein, large, P2 | -0.0281663 |
| RPL34 | ribosomal protein L34 | -0.0278889 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0277245 |
| CBX3 | chromobox homolog 3 | -0.027558 |
| DTNA | dystrobrevin, alpha | -0.02665 |
| IKBIP | IKBKB interacting protein | -0.0266068 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0265771 |
| HELZ | helicase with zinc finger | -0.0261266 |
| CLTC | clathrin, heavy chain (Hc) | -0.025756 |
| SNX13 | sorting nexin 13 | -0.0255937 |
| LOX | lysyl oxidase | -0.0255623 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0255443 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0255103 |
| SEC61G | Sec61 gamma subunit | -0.0254504 |
| S100A10 | S100 calcium binding protein A10 | -0.0253673 |
| OSMR | oncostatin M receptor | -0.0252077 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0251384 |
| ZNF148 | zinc finger protein 148 | -0.0249396 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.024613 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0245476 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0245278 |
| PTK2 | protein tyrosine kinase 2 | -0.0240406 |
| RASA2 | RAS p21 protein activator 2 | -0.0240038 |
| USP47 | ubiquitin specific peptidase 47 | -0.0239301 |
| RPLP1 | ribosomal protein, large, P1 | -0.0238243 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0235905 |
| FAM13A | family with sequence similarity 13, member A | -0.0229635 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0228681 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0227535 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0223469 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0223325 |
| RPS19 | ribosomal protein S19 | -0.0223324 |
| ASPH | aspartate beta-hydroxylase | -0.0221131 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0220657 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0219311 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0219044 |
| PHF21A | PHD finger protein 21A | -0.0218882 |
| SON | SON DNA binding protein | -0.0218096 |
| TMEM263 | transmembrane protein 263 | -0.0217535 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.021501 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0214025 |
| CALU | calumenin | -0.0212073 |
| CALN1 | calneuron 1 | -0.021159 |
| TUBB | tubulin, beta class I | -0.0210804 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0209846 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0209804 |
| PDS5A | PDS5 cohesin associated factor A | -0.0209192 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.020903 |
| PHIP | pleckstrin homology domain interacting protein | -0.0207247 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0207181 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0206215 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0204201 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0203586 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0200809 |
| SEPTIN7 | septin 7 | -0.0199868 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0199154 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0197353 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0197132 |
| NUP153 | nucleoporin 153kDa | -0.0195411 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0194498 |
| VEGFC | vascular endothelial growth factor C | -0.0193917 |
