| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.210221 |
| AHNAK | AHNAK nucleoprotein | 0.158737 |
| CANX | calnexin | 0.104135 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0866001 |
| LDHA | lactate dehydrogenase A | 0.0859848 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0849611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0817448 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0766686 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0757937 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0743225 |
| ENO1 | enolase 1, (alpha) | 0.0679533 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0648819 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0641543 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0599539 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0547364 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0531196 |
| RAD51B | RAD51 paralog B | 0.0530022 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0499896 |
| ZNF638 | zinc finger protein 638 | 0.0486777 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0480677 |
| APP | amyloid beta (A4) precursor protein | 0.0476301 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0469866 |
| HDLBP | high density lipoprotein binding protein | 0.046682 |
| MED13L | mediator complex subunit 13-like | 0.0461167 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0437871 |
| EZR | ezrin | 0.0434151 |
| DSPP | dentin sialophosphoprotein | 0.0434054 |
| SERINC5 | serine incorporator 5 | 0.0431736 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0429674 |
| MCL1 | myeloid cell leukemia 1 | 0.0427781 |
| PHF3 | PHD finger protein 3 | 0.0424699 |
| MYOF | myoferlin | 0.0423234 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0420618 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0419833 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0412901 |
| PRELID2 | PRELI domain containing 2 | 0.0410878 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.04078 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0405618 |
| PGK1 | phosphoglycerate kinase 1 | 0.0403262 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0403153 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0400647 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0395339 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0393886 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0393599 |
| TPM4 | tropomyosin 4 | 0.0393186 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0391956 |
| PCBP2 | poly(rC) binding protein 2 | 0.0390128 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0381996 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0376738 |
| PKM | pyruvate kinase, muscle | 0.0373105 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0372975 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0369431 |
| FLNB | filamin B, beta | 0.03676 |
| JMJD1C | jumonji domain containing 1C | 0.0363549 |
| BPTF | bromodomain PHD finger transcription factor | 0.03635 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0362188 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0361992 |
| ATM | ATM serine/threonine kinase | 0.0361127 |
| SDC4 | syndecan 4 | 0.0359894 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0350326 |
| ASPH | aspartate beta-hydroxylase | 0.034714 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0344737 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0340907 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0335565 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0333292 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0332528 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0329505 |
| SMYD3 | SET and MYND domain containing 3 | 0.0326648 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0326498 |
| WWC2 | WW and C2 domain containing 2 | 0.0319297 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0315618 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0315214 |
| VCL | vinculin | 0.0314658 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0310596 |
| SLC38A2 | solute carrier family 38, member 2 | 0.030992 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0307661 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.030734 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0306117 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0306081 |
| TXNRD1 | thioredoxin reductase 1 | 0.0305906 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.030501 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0303434 |
| ERBIN | erbb2 interacting protein | 0.0301607 |
| TENM3 | teneurin transmembrane protein 3 | 0.0301099 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0300547 |
| MYO9A | myosin IXA | 0.029956 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0299292 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0296247 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0295753 |
| PRRC2C | proline-rich coiled-coil 2C | 0.029545 |
| EHBP1 | EH domain binding protein 1 | 0.0292885 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0292143 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0291992 |
| EXOC4 | exocyst complex component 4 | 0.0289396 |
| MSI2 | musashi RNA-binding protein 2 | 0.0288022 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0287118 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.02858 |
| TMF1 | TATA element modulatory factor 1 | 0.0283816 |
| GOLGB1 | golgin B1 | 0.0283458 |
| MATR3 | matrin 3 | 0.0279618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.243773 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.12003 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.084326 |
| MT2A | metallothionein 2A | -0.0525743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0421916 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0416788 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0384269 |
| PTMA | prothymosin, alpha | -0.0369294 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0339578 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316536 |
| POTEF | POTE ankyrin domain family, member F | -0.0315747 |
| RPS6 | ribosomal protein S6 | -0.0307474 |
| RPS8 | ribosomal protein S8 | -0.0255761 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0253909 |
| FHIT | fragile histidine triad | -0.0246384 |
| RPL34 | ribosomal protein L34 | -0.0226171 |
| TUBA1B | tubulin, alpha 1b | -0.0218218 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0217341 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0216178 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0211714 |
| HELZ | helicase with zinc finger | -0.0205274 |
| RPLP2 | ribosomal protein, large, P2 | -0.0200911 |
| HMGA1 | high mobility group AT-hook 1 | -0.0195278 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0185756 |
| WWOX | WW domain containing oxidoreductase | -0.0180949 |
| RPS15 | ribosomal protein S15 | -0.0180037 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.017935 |
| UBC | ubiquitin C | -0.0174632 |
| RPL32 | ribosomal protein L32 | -0.0174535 |
| RPL35A | ribosomal protein L35a | -0.017288 |
| PRDX2 | peroxiredoxin 2 | -0.0170291 |
| RPL9 | ribosomal protein L9 | -0.0169074 |
| RPS21 | ribosomal protein S21 | -0.016555 |
| B2M | beta-2-microglobulin | -0.0163564 |
| ANKRD37 | ankyrin repeat domain 37 | -0.016189 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0157069 |
| RPS29 | ribosomal protein S29 | -0.015506 |
| ACTG1 | actin gamma 1 | -0.0154207 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0153872 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0153798 |
| PFN1 | profilin 1 | -0.0153504 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0151281 |
| RPS23 | ribosomal protein S23 | -0.0150602 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0149522 |
| HMGB1 | high mobility group box 1 | -0.0148934 |
| RPL28 | ribosomal protein L28 | -0.0146749 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0138302 |
| RPL8 | ribosomal protein L8 | -0.0138268 |
| RPLP0 | ribosomal protein, large, P0 | -0.0134853 |
| RPL15 | ribosomal protein L15 | -0.0134681 |
| RPS16 | ribosomal protein S16 | -0.0134268 |
| TMSB10 | thymosin beta 10 | -0.0131185 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0131176 |
| TTC21B | tetratricopeptide repeat domain 21B | -0.0130699 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0130362 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0128999 |
| H2AZ1 | H2A.Z variant histone 1 | -0.0125881 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0124183 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0123792 |
| HELLS | helicase, lymphoid-specific | -0.0123547 |
| RPS20 | ribosomal protein S20 | -0.0120209 |
| WDR45B | WD repeat domain 45B | -0.0118642 |
| SEC24D | SEC24 family member D | -0.0118229 |
| RPS24 | ribosomal protein S24 | -0.0117986 |
| RPS5 | ribosomal protein S5 | -0.0117618 |
| RPL7A | ribosomal protein L7a | -0.0115955 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0114952 |
| RPLP1 | ribosomal protein, large, P1 | -0.0114228 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0112878 |
| RBBP4 | retinoblastoma binding protein 4 | -0.0112275 |
| RPL5 | ribosomal protein L5 | -0.011117 |
| RPS2 | ribosomal protein S2 | -0.0110509 |
| FAM117B | family with sequence similarity 117, member B | -0.010889 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0108825 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.010844 |
| STMN1 | stathmin 1 | -0.0107631 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0106761 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0105339 |
| GHITM | growth hormone inducible transmembrane protein | -0.0103785 |
| RPL27 | ribosomal protein L27 | -0.0103713 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0103582 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0103066 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -0.0102862 |
| S100A9 | S100 calcium binding protein A9 | -0.0102293 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0102208 |
| SESN2 | sestrin 2 | -0.0101881 |
| MCM4 | minichromosome maintenance complex component 4 | -0.0101304 |
| KIF2C | kinesin family member 2C | -0.0101257 |
| SEC61G | Sec61 gamma subunit | -0.0101185 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00997927 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00996143 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.00989623 |
| RPS13 | ribosomal protein S13 | -0.00983759 |
| RPS17 | ribosomal protein S17 | -0.00980635 |
| ADM | adrenomedullin | -0.00971529 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.00970707 |
| VEGFA | vascular endothelial growth factor A | -0.00962287 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00961515 |
| CHMP2B | charged multivesicular body protein 2B | -0.00956973 |
| RPS19 | ribosomal protein S19 | -0.00953106 |
