| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APP | amyloid beta (A4) precursor protein | 0.11905 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0792165 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0703225 |
| PTMA | prothymosin, alpha | 0.0673311 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0596963 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0591039 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0589037 |
| TXNRD1 | thioredoxin reductase 1 | 0.0570124 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0527076 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0522322 |
| PKM | pyruvate kinase, muscle | 0.0520063 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0500507 |
| EGR1 | early growth response 1 | 0.0473271 |
| AHNAK | AHNAK nucleoprotein | 0.0448731 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0429437 |
| PLEC | plectin | 0.0413223 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0408195 |
| EZR | ezrin | 0.0400793 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0375527 |
| MYEOV | myeloma overexpressed | 0.0370452 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0369707 |
| LDHA | lactate dehydrogenase A | 0.0360515 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0358819 |
| CANX | calnexin | 0.0356525 |
| SQSTM1 | sequestosome 1 | 0.0353479 |
| SDC4 | syndecan 4 | 0.0351123 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0343688 |
| FLNA | filamin A, alpha | 0.0339117 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0334984 |
| KRT7 | keratin 7, type II | 0.0326813 |
| MATR3 | matrin 3 | 0.0323942 |
| SET | SET nuclear proto-oncogene | 0.031762 |
| B2M | beta-2-microglobulin | 0.0311315 |
| SEPTIN9 | septin 9 | 0.0303258 |
| SFTPA2 | surfactant protein A2 | 0.0298251 |
| MCL1 | myeloid cell leukemia 1 | 0.0296199 |
| ACTN4 | actinin, alpha 4 | 0.0288354 |
| EREG | epiregulin | 0.0281716 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | 0.0278402 |
| RNF213 | ring finger protein 213 | 0.0276488 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0262711 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0259867 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0259011 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0257934 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.025791 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0257544 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0246361 |
| FAT1 | FAT atypical cadherin 1 | 0.0245859 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0245859 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0245334 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0244046 |
| FTL | ferritin, light polypeptide | 0.0243516 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0241281 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0226284 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0226167 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0225912 |
| CD164 | CD164 molecule, sialomucin | 0.0224763 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0223453 |
| CCNL1 | cyclin L1 | 0.0222028 |
| CLDN4 | claudin 4 | 0.021963 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0218856 |
| DSPP | dentin sialophosphoprotein | 0.0218125 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0212409 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0210543 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0209598 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0207196 |
| TMSB4X | thymosin beta 4, X-linked | 0.0205261 |
| ATXN1 | ataxin 1 | 0.0205157 |
| GDA | guanine deaminase | 0.0204834 |
| HLA-C | major histocompatibility complex, class I, C | 0.0203174 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0202288 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0201139 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0200365 |
| ITGB6 | integrin, beta 6 | 0.0196884 |
| TKT | transketolase | 0.0196881 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0195692 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0194242 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0191222 |
| PCBP2 | poly(rC) binding protein 2 | 0.0190037 |
| HMGB2 | high mobility group box 2 | 0.0188992 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0187603 |
| ANXA11 | annexin A11 | 0.0187192 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0186949 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0186713 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0185923 |
| SKIL | SKI-like proto-oncogene | 0.0185744 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0185726 |
| LMNA | lamin A/C | 0.0185246 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.0185115 |
| ARGLU1 | arginine and glutamate rich 1 | 0.01851 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0184377 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0184262 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0184051 |
| CALR | calreticulin | 0.0181318 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0180235 |
| TUBB | tubulin, beta class I | 0.0179393 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0178893 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0178819 |
| AATF | apoptosis antagonizing transcription factor | 0.0177389 |
| RPS4X | ribosomal protein S4, X-linked | 0.0176095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.150898 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107857 |
| PRELID2 | PRELI domain containing 2 | -0.0750899 |
| GOLGA4 | golgin A4 | -0.0663215 |
| FNDC3B | fibronectin type III domain containing 3B | -0.060931 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0598758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0594446 |
| NDRG1 | N-myc downstream regulated 1 | -0.0550704 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0538757 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0519442 |
| SMYD3 | SET and MYND domain containing 3 | -0.0412578 |
| TMSB10 | thymosin beta 10 | -0.0399341 |
| FLNB | filamin B, beta | -0.0373135 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0372211 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0357552 |
| SETD5 | SET domain containing 5 | -0.0354686 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.034529 |
| BPTF | bromodomain PHD finger transcription factor | -0.0326353 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0313794 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0311207 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0308092 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.03049 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300435 |
| DIAPH3 | diaphanous-related formin 3 | -0.0299469 |
| CDCP1 | CUB domain containing protein 1 | -0.0294907 |
| IRS2 | insulin receptor substrate 2 | -0.0281881 |
| ANXA2 | annexin A2 | -0.0280992 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0277235 |
| FHIT | fragile histidine triad | -0.0276458 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0275919 |
| NKTR | natural killer cell triggering receptor | -0.0274109 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0270437 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0266301 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0265748 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.02632 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0252933 |
| SCFD1 | sec1 family domain containing 1 | -0.0249881 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0246134 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0245202 |
| MT1X | metallothionein 1X | -0.0244045 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0243412 |
| WDR45B | WD repeat domain 45B | -0.0243187 |
| RPS2 | ribosomal protein S2 | -0.0242588 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.02385 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0238411 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0238331 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0235755 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.023507 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0233452 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0232423 |
| RUNX1 | runt-related transcription factor 1 | -0.0232017 |
| HMGA1 | high mobility group AT-hook 1 | -0.0231323 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0227309 |
| FNIP1 | folliculin interacting protein 1 | -0.0225307 |
| HMGA2 | high mobility group AT-hook 2 | -0.0224708 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0223847 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0223679 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0223099 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0222675 |
| BBX | bobby sox homolog (Drosophila) | -0.0221404 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0219554 |
| HELZ | helicase with zinc finger | -0.0219535 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0218963 |
| RBM26 | RNA binding motif protein 26 | -0.0217715 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0214473 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0214256 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.021175 |
| CENPP | centromere protein P | -0.021146 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0211254 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0207932 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0206534 |
| MEF2A | myocyte enhancer factor 2A | -0.0205005 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0204004 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.020224 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0199236 |
| USP47 | ubiquitin specific peptidase 47 | -0.0198564 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0196977 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0195867 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.019557 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0194425 |
| SFXN1 | sideroflexin 1 | -0.0190847 |
| SEC24A | SEC24 family member A | -0.019079 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0190645 |
| CDK13 | cyclin-dependent kinase 13 | -0.0189724 |
| HM13 | histocompatibility (minor) 13 | -0.0187977 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0187919 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0187842 |
| ZFR | zinc finger RNA binding protein | -0.0187778 |
| ATP13A3 | ATPase type 13A3 | -0.0186813 |
| CLMN | calmin (calponin-like, transmembrane) | -0.01864 |
| SNX9 | sorting nexin 9 | -0.0184139 |
| CENPF | centromere protein F, 350/400kDa | -0.0183166 |
| KIAA1328 | KIAA1328 | -0.0182737 |
| ANKRD26 | ankyrin repeat domain 26 | -0.0179585 |
| TMEM245 | transmembrane protein 245 | -0.0178905 |
| ANKRD36B | ankyrin repeat domain 36B | -0.0177855 |
| ARFGEF3 | ARFGEF family member 3 | -0.0177672 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0177076 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0176883 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0176505 |
