| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.115266 |
| ASPH | aspartate beta-hydroxylase | 0.0944752 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0784746 |
| MCL1 | myeloid cell leukemia 1 | 0.0637368 |
| CANX | calnexin | 0.0633088 |
| PLEC | plectin | 0.0606598 |
| CD44 | CD44 molecule (Indian blood group) | 0.0598872 |
| ENO1 | enolase 1, (alpha) | 0.05925 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0573153 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0543559 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0454872 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0440346 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0422427 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.041669 |
| LDHA | lactate dehydrogenase A | 0.0410823 |
| VCL | vinculin | 0.041012 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0398314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0387564 |
| EGR1 | early growth response 1 | 0.0375792 |
| THBS1 | thrombospondin 1 | 0.0356214 |
| CLIC4 | chloride intracellular channel 4 | 0.0347428 |
| INHBA | inhibin, beta A | 0.034107 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0331891 |
| CALR | calreticulin | 0.032882 |
| PKM | pyruvate kinase, muscle | 0.0318669 |
| COL5A1 | collagen, type V, alpha 1 | 0.031539 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0311892 |
| AHNAK | AHNAK nucleoprotein | 0.0305664 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0296125 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0292748 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0289798 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0283988 |
| ATXN1 | ataxin 1 | 0.0281403 |
| MLPH | melanophilin | 0.0272096 |
| IL1B | interleukin 1, beta | 0.0256254 |
| APP | amyloid beta (A4) precursor protein | 0.0255011 |
| IGF2 | insulin-like growth factor 2 | 0.0250041 |
| CALU | calumenin | 0.0240353 |
| CDH13 | cadherin 13 | 0.0239212 |
| PCBP3 | poly(rC) binding protein 3 | 0.0237899 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0237572 |
| MSN | moesin | 0.02323 |
| TENM2 | teneurin transmembrane protein 2 | 0.0231027 |
| GLIS3 | GLIS family zinc finger 3 | 0.0226931 |
| LAMB3 | laminin, beta 3 | 0.0224084 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0222353 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0217797 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0209813 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.020689 |
| LMNA | lamin A/C | 0.0197554 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0197238 |
| VMP1 | vacuole membrane protein 1 | 0.0192356 |
| DST | dystonin | 0.0188832 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0188029 |
| TNNC1 | troponin C type 1 (slow) | 0.0187171 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0183512 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.018197 |
| TPM4 | tropomyosin 4 | 0.0178854 |
| VEGFA | vascular endothelial growth factor A | 0.0178472 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0177516 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0172058 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0171795 |
| STC1 | stanniocalcin 1 | 0.0170734 |
| YBX3 | Y box binding protein 3 | 0.0169616 |
| EMP1 | epithelial membrane protein 1 | 0.0165793 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0165693 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0165429 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0165208 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0164453 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0163237 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0162919 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0162867 |
| PDE10A | phosphodiesterase 10A | 0.0162161 |
| RAI14 | retinoic acid induced 14 | 0.0161736 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0161195 |
| COL4A2 | collagen, type IV, alpha 2 | 0.015748 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0156024 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0155246 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0154649 |
| TGFB1 | transforming growth factor, beta 1 | 0.0153844 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.015038 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.014996 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0149851 |
| LOXL2 | lysyl oxidase-like 2 | 0.0149403 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0148591 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0148325 |
| SET | SET nuclear proto-oncogene | 0.0148119 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0147543 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0146644 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0146026 |
| SDC4 | syndecan 4 | 0.0143364 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.014335 |
| TXNIP | thioredoxin interacting protein | 0.0143323 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0143314 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0142032 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.014192 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0141403 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0140617 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0138893 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0138419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.304061 |
| MT2A | metallothionein 2A | -0.103776 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0676078 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0427874 |
| HMGA2 | high mobility group AT-hook 2 | -0.0346638 |
| RPS6 | ribosomal protein S6 | -0.0322157 |
| NDRG1 | N-myc downstream regulated 1 | -0.032136 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0315256 |
| FAM13A | family with sequence similarity 13, member A | -0.0293827 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0291201 |
| DTNA | dystrobrevin, alpha | -0.0286921 |
| TMSB10 | thymosin beta 10 | -0.0259393 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0253284 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0244157 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.024297 |
| RNF145 | ring finger protein 145 | -0.0239616 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0239406 |
| RPLP1 | ribosomal protein, large, P1 | -0.0236998 |
| RPS19 | ribosomal protein S19 | -0.0209022 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0206021 |
| SPAG9 | sperm associated antigen 9 | -0.0205102 |
| GOLGA4 | golgin A4 | -0.0199418 |
| SETD5 | SET domain containing 5 | -0.0196209 |
| RPL34 | ribosomal protein L34 | -0.0185943 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0182731 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180884 |
| MAP1B | microtubule-associated protein 1B | -0.0178633 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0176385 |
| FTL | ferritin, light polypeptide | -0.0173235 |
| USP3 | ubiquitin specific peptidase 3 | -0.0170731 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0170303 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0168579 |
| RPL28 | ribosomal protein L28 | -0.0166683 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0163215 |
| MMP12 | matrix metallopeptidase 12 | -0.0161126 |
| VIM | vimentin | -0.0158621 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0155858 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0154828 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0154441 |
| RPS12 | ribosomal protein S12 | -0.0153022 |
| FOXJ3 | forkhead box J3 | -0.0151408 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0149857 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0147677 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0147063 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.01459 |
| ZNF638 | zinc finger protein 638 | -0.0144056 |
| PTK2 | protein tyrosine kinase 2 | -0.014338 |
| RAD51B | RAD51 paralog B | -0.0142315 |
| RPS8 | ribosomal protein S8 | -0.0141488 |
| RPL9 | ribosomal protein L9 | -0.0140508 |
| ZNF292 | zinc finger protein 292 | -0.0139058 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0135497 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0134704 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0130568 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0128914 |
| MATR3 | matrin 3 | -0.0128791 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0128325 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0127197 |
| RPL32 | ribosomal protein L32 | -0.0125034 |
| MT1X | metallothionein 1X | -0.0123009 |
| ATP13A3 | ATPase type 13A3 | -0.0122679 |
| QKI | QKI, KH domain containing, RNA binding | -0.0122386 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0121736 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0121623 |
| ADM | adrenomedullin | -0.0121331 |
| RPL23 | ribosomal protein L23 | -0.0121226 |
| NAV2 | neuron navigator 2 | -0.0120275 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0119417 |
| POM121 | POM121 transmembrane nucleoporin | -0.0118427 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0117018 |
| MED13L | mediator complex subunit 13-like | -0.0116197 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0114592 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0113951 |
| RPL11 | ribosomal protein L11 | -0.0112797 |
| SEC24A | SEC24 family member A | -0.011073 |
| RPS16 | ribosomal protein S16 | -0.0109513 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0109381 |
| ZFR | zinc finger RNA binding protein | -0.0109287 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0109049 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0108606 |
| RPS20 | ribosomal protein S20 | -0.0108089 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.010491 |
| FNBP1 | formin binding protein 1 | -0.0104742 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0100847 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0100824 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0100572 |
| RPS24 | ribosomal protein S24 | -0.010042 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0100404 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.00999805 |
| CENPF | centromere protein F, 350/400kDa | -0.009857 |
| KIF4A | kinesin family member 4A | -0.00981413 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.00975344 |
| HELZ | helicase with zinc finger | -0.0095401 |
| RBM25 | RNA binding motif protein 25 | -0.00951171 |
| RPS29 | ribosomal protein S29 | -0.00942083 |
| SPIDR | scaffolding protein involved in DNA repair | -0.00937522 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.00936194 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0092763 |
| RNF24 | ring finger protein 24 | -0.00920189 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00918286 |
