| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.306583 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.194732 |
| COL6A3 | collagen, type VI, alpha 3 | 0.163694 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0820176 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0762731 |
| VEGFA | vascular endothelial growth factor A | 0.0750134 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0749812 |
| LDHA | lactate dehydrogenase A | 0.0679995 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0565291 |
| VCAN | versican | 0.0551702 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0547459 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0517392 |
| PLEC | plectin | 0.0487945 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0429211 |
| FAT1 | FAT atypical cadherin 1 | 0.0425303 |
| ARRDC3 | arrestin domain containing 3 | 0.0417829 |
| CANX | calnexin | 0.0406904 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.040385 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0401411 |
| CD44 | CD44 molecule (Indian blood group) | 0.0357319 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0354619 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.034849 |
| FBN1 | fibrillin 1 | 0.0347685 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0342941 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0332663 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0317794 |
| IL6ST | interleukin 6 signal transducer | 0.0312171 |
| IL6 | interleukin 6 | 0.0312087 |
| COL5A1 | collagen, type V, alpha 1 | 0.0277896 |
| ASPH | aspartate beta-hydroxylase | 0.0275862 |
| TPM4 | tropomyosin 4 | 0.0273037 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0267287 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0265764 |
| APP | amyloid beta (A4) precursor protein | 0.0259617 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0252257 |
| AXL | AXL receptor tyrosine kinase | 0.0251628 |
| SMAD3 | SMAD family member 3 | 0.0247507 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0242066 |
| HMGA2 | high mobility group AT-hook 2 | 0.0240483 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0236134 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0230711 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0230472 |
| YEATS2 | YEATS domain containing 2 | 0.0227466 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0225892 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0215683 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0215622 |
| NRP1 | neuropilin 1 | 0.0214616 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.021443 |
| MSN | moesin | 0.021422 |
| NAV2 | neuron navigator 2 | 0.0211465 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0209404 |
| RIGI | RNA sensor RIG-I | 0.0206478 |
| TNS1 | tensin 1 | 0.0192441 |
| RND3 | Rho family GTPase 3 | 0.0191922 |
| VMP1 | vacuole membrane protein 1 | 0.0190367 |
| NAV1 | neuron navigator 1 | 0.0189214 |
| CLIC4 | chloride intracellular channel 4 | 0.0188254 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0187933 |
| AHNAK | AHNAK nucleoprotein | 0.0187042 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0184941 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0183515 |
| STC1 | stanniocalcin 1 | 0.0182028 |
| SDC4 | syndecan 4 | 0.018122 |
| GLIS3 | GLIS family zinc finger 3 | 0.0180282 |
| NOTCH2 | notch 2 | 0.0179792 |
| CALR | calreticulin | 0.0177852 |
| ANO6 | anoctamin 6 | 0.017694 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0176908 |
| MX2 | MX dynamin-like GTPase 2 | 0.0176623 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0176566 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0174768 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0173135 |
| FAM20C | family with sequence similarity 20, member C | 0.0170607 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0170423 |
| SFTPA2 | surfactant protein A2 | 0.0168608 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0168044 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0167686 |
| HAS2 | hyaluronan synthase 2 | 0.016745 |
| MCL1 | myeloid cell leukemia 1 | 0.0167442 |
| INHBA | inhibin, beta A | 0.0166163 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0163557 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0162434 |
| LOXL2 | lysyl oxidase-like 2 | 0.0160074 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0159996 |
| STC2 | stanniocalcin 2 | 0.0157938 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0157931 |
| TLN1 | talin 1 | 0.0156587 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0156306 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0156158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0155955 |
| HYOU1 | hypoxia up-regulated 1 | 0.0155929 |
| CCND1 | cyclin D1 | 0.0153672 |
| ZNF148 | zinc finger protein 148 | 0.0153424 |
| TPM3 | tropomyosin 3 | 0.0151159 |
| SON | SON DNA binding protein | 0.0150345 |
| LAMB1 | laminin, beta 1 | 0.0149053 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0148427 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0148122 |
| LIMA1 | LIM domain and actin binding 1 | 0.0147748 |
| FOXP1 | forkhead box P1 | 0.0147336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.173609 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.165702 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143631 |
| COL1A1 | collagen, type I, alpha 1 | -0.117158 |
| TMSB10 | thymosin beta 10 | -0.105488 |
| MT2A | metallothionein 2A | -0.0965086 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0936931 |
| RPL35A | ribosomal protein L35a | -0.0799762 |
| IER3 | immediate early response 3 | -0.0710397 |
| RPS8 | ribosomal protein S8 | -0.0700172 |
| NDRG1 | N-myc downstream regulated 1 | -0.067645 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0640683 |
| FTL | ferritin, light polypeptide | -0.0570662 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0541032 |
| PTMA | prothymosin, alpha | -0.0538415 |
| COL1A2 | collagen, type I, alpha 2 | -0.0487832 |
| RPS6 | ribosomal protein S6 | -0.0487643 |
| CADM1 | cell adhesion molecule 1 | -0.0455409 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0449955 |
| RPLP2 | ribosomal protein, large, P2 | -0.03881 |
| RPL11 | ribosomal protein L11 | -0.0388071 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384826 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0380899 |
| HLA-B | major histocompatibility complex, class I, B | -0.0371751 |
| ACTG1 | actin gamma 1 | -0.0365881 |
| RPS24 | ribosomal protein S24 | -0.0362391 |
| RPL28 | ribosomal protein L28 | -0.0356073 |
| RPL34 | ribosomal protein L34 | -0.0349793 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0343584 |
| GNAS | GNAS complex locus | -0.0341478 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0339101 |
| S100A9 | S100 calcium binding protein A9 | -0.0324851 |
| MTDH | metadherin | -0.0321465 |
| RPL37A | ribosomal protein L37a | -0.0320276 |
| RPL26 | ribosomal protein L26 | -0.0318086 |
| RPS25 | ribosomal protein S25 | -0.0313194 |
| RPLP1 | ribosomal protein, large, P1 | -0.0310852 |
| RPS20 | ribosomal protein S20 | -0.030084 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0299402 |
| RPL9 | ribosomal protein L9 | -0.0293616 |
| RRBP1 | ribosome binding protein 1 | -0.0293564 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0291896 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0290667 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0290078 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.028887 |
| RPS13 | ribosomal protein S13 | -0.0287096 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0285931 |
| CAVIN1 | caveolae associated protein 1 | -0.0278786 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0276527 |
| RPS21 | ribosomal protein S21 | -0.0273405 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0267211 |
| ANXA2 | annexin A2 | -0.0266847 |
| S100A10 | S100 calcium binding protein A10 | -0.026544 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0263382 |
| RPL38 | ribosomal protein L38 | -0.0243696 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0239544 |
| RPL23 | ribosomal protein L23 | -0.023927 |
| RPS3 | ribosomal protein S3 | -0.0237805 |
| RPL30 | ribosomal protein L30 | -0.0236248 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0233567 |
| RPL12 | ribosomal protein L12 | -0.0231673 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0230173 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.022967 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0228838 |
| RPL31 | ribosomal protein L31 | -0.0224953 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0224479 |
| RPS29 | ribosomal protein S29 | -0.0223767 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0218814 |
| FAM162A | family with sequence similarity 162, member A | -0.0217388 |
| VDAC1 | voltage-dependent anion channel 1 | -0.021619 |
| ADM | adrenomedullin | -0.0214498 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0213963 |
| RPS16 | ribosomal protein S16 | -0.0212166 |
| ZNF292 | zinc finger protein 292 | -0.0212055 |
| RPL37 | ribosomal protein L37 | -0.0211495 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0204965 |
| RPS12 | ribosomal protein S12 | -0.0202822 |
| RPS23 | ribosomal protein S23 | -0.020047 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0200452 |
| RPL8 | ribosomal protein L8 | -0.0198323 |
| DSTN | destrin (actin depolymerizing factor) | -0.0197432 |
| TMEM41B | transmembrane protein 41B | -0.0197212 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0196788 |
| RPL36 | ribosomal protein L36 | -0.0196326 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.019507 |
| RPS11 | ribosomal protein S11 | -0.0192875 |
| RPS14 | ribosomal protein S14 | -0.0191453 |
| RPS10 | ribosomal protein S10 | -0.0191108 |
| RPS19 | ribosomal protein S19 | -0.0190712 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.018886 |
| SEC61G | Sec61 gamma subunit | -0.0188644 |
| LOX | lysyl oxidase | -0.0185768 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0180187 |
| QKI | QKI, KH domain containing, RNA binding | -0.0179927 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0178556 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0177296 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0176059 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0175784 |
| TGFB1 | transforming growth factor, beta 1 | -0.0175386 |
| RACK1 | receptor for activated C kinase 1 | -0.0175032 |
