| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0569449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0479025 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044907 |
| TXNRD1 | thioredoxin reductase 1 | 0.0390229 |
| LMO7 | LIM domain 7 | 0.0337883 |
| LYZ | lysozyme | 0.033338 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0281183 |
| STK24 | serine/threonine kinase 24 | 0.0272123 |
| MSN | moesin | 0.025022 |
| EZR | ezrin | 0.0250059 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0246836 |
| FAT1 | FAT atypical cadherin 1 | 0.0246156 |
| RPL21 | ribosomal protein L21 | 0.0241858 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0235182 |
| SET | SET nuclear proto-oncogene | 0.022852 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223736 |
| TPM3 | tropomyosin 3 | 0.0222098 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0221903 |
| TMC5 | transmembrane channel-like 5 | 0.0216674 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0211832 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0211675 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0207552 |
| KRT18 | keratin 18, type I | 0.0207403 |
| MCL1 | myeloid cell leukemia 1 | 0.0207013 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0198911 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0198878 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0196066 |
| TJP1 | tight junction protein 1 | 0.0194763 |
| POTEF | POTE ankyrin domain family, member F | 0.0189207 |
| ANXA11 | annexin A11 | 0.0184461 |
| ABHD2 | abhydrolase domain containing 2 | 0.0182211 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0181332 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0180916 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0179624 |
| PTK2 | protein tyrosine kinase 2 | 0.01793 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0176154 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0171983 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0169184 |
| EGR1 | early growth response 1 | 0.0168984 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0168833 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.016628 |
| RTN4 | reticulon 4 | 0.0164507 |
| RPS18 | ribosomal protein S18 | 0.0161172 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0159183 |
| PLEC | plectin | 0.0158752 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0158584 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0154538 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0154231 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0154146 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0153602 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0150024 |
| YBX1 | Y box binding protein 1 | 0.0150011 |
| SFPQ | splicing factor proline/glutamine-rich | 0.014968 |
| KRT8 | keratin 8, type II | 0.0149478 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0147589 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0146799 |
| SEPTIN9 | septin 9 | 0.0145602 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0144645 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0144445 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0143412 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0141231 |
| MYO5B | myosin VB | 0.0141149 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0140881 |
| SMAD3 | SMAD family member 3 | 0.0140408 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.0140406 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0140121 |
| VEGFA | vascular endothelial growth factor A | 0.0138814 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0138628 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0138092 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0136046 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0135545 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0135401 |
| CLDN4 | claudin 4 | 0.0135348 |
| WWC1 | WW and C2 domain containing 1 | 0.0131144 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0127711 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0127195 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0126642 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0125571 |
| CANX | calnexin | 0.0124384 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0123879 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0122568 |
| PLK2 | polo-like kinase 2 | 0.0122489 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0121612 |
| TSPAN3 | tetraspanin 3 | 0.0121222 |
| EPS8L1 | EPS8-like 1 | 0.0120558 |
| PCBP2 | poly(rC) binding protein 2 | 0.0118286 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0117265 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0116904 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0115837 |
| PDZD8 | PDZ domain containing 8 | 0.0115123 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0114132 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0113634 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0113289 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0110285 |
| ENO1 | enolase 1, (alpha) | 0.0109644 |
| CALR | calreticulin | 0.0109216 |
| RPL7 | ribosomal protein L7 | 0.0108798 |
| IPO7 | importin 7 | 0.0108372 |
| SKIL | SKI-like proto-oncogene | 0.0107948 |
| JMJD1C | jumonji domain containing 1C | 0.0107876 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0697676 |
| FTL | ferritin, light polypeptide | -0.0544362 |
| NDRG1 | N-myc downstream regulated 1 | -0.0536081 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.052736 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0336772 |
| INTS6 | integrator complex subunit 6 | -0.0329184 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0290681 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0287228 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0253576 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245847 |
| FBXO32 | F-box protein 32 | -0.0245412 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0218541 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0213355 |
| RTN3 | reticulon 3 | -0.0210487 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0209123 |
| TMSB10 | thymosin beta 10 | -0.0207594 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0200301 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0194738 |
| MORF4L2 | mortality factor 4 like 2 | -0.0181286 |
| RPLP1 | ribosomal protein, large, P1 | -0.0177631 |
| RPL34 | ribosomal protein L34 | -0.0176273 |
| GNAS | GNAS complex locus | -0.0170309 |
| HM13 | histocompatibility (minor) 13 | -0.0169446 |
| RPS24 | ribosomal protein S24 | -0.0163078 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0160862 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0160305 |
| FAM13A | family with sequence similarity 13, member A | -0.0157191 |
| H1-0 | H1.0 linker histone | -0.0154058 |
| FRY | furry homolog (Drosophila) | -0.0152473 |
| KRT20 | keratin 20, type I | -0.0152267 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0151858 |
| RPL13A | ribosomal protein L13a | -0.0150151 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.014997 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0142889 |
| AGR2 | anterior gradient 2 | -0.0142867 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0141807 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0138331 |
| PRELID2 | PRELI domain containing 2 | -0.0136586 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0136557 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.013458 |
| RPL28 | ribosomal protein L28 | -0.0128913 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0126709 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0125238 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0124294 |
| RPS21 | ribosomal protein S21 | -0.0123132 |
| ACTG1 | actin gamma 1 | -0.0123096 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0122645 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0120946 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0120319 |
| SEC24A | SEC24 family member A | -0.0117529 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0116011 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0115654 |
| RRBP1 | ribosome binding protein 1 | -0.0115535 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0114078 |
| CALU | calumenin | -0.0113768 |
| GSN | gelsolin | -0.0111864 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0110137 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0108285 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0106343 |
| ARF1 | ADP-ribosylation factor 1 | -0.0106217 |
| WDR45B | WD repeat domain 45B | -0.0105765 |
| CDK13 | cyclin-dependent kinase 13 | -0.0105732 |
| SERF2 | small EDRK-rich factor 2 | -0.0105238 |
| RPS3 | ribosomal protein S3 | -0.010495 |
| LOC112694756 | uncharaterized LOC112694756 | -0.010476 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0104619 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0104516 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0103038 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0103035 |
| ANXA2 | annexin A2 | -0.0100793 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00998379 |
| KLF6 | Kruppel-like factor 6 | -0.00988409 |
| USP3 | ubiquitin specific peptidase 3 | -0.00954456 |
| FAM162A | family with sequence similarity 162, member A | -0.00951743 |
| TMEM263 | transmembrane protein 263 | -0.0094612 |
| RPL30 | ribosomal protein L30 | -0.00940362 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.00927598 |
| RPL12 | ribosomal protein L12 | -0.00920325 |
| SEPTIN2 | septin 2 | -0.0091434 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.00900421 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00900413 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0089698 |
| NPR2 | natriuretic peptide receptor 2 | -0.00896462 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.00895789 |
| TMEM41B | transmembrane protein 41B | -0.00895328 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00881878 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.00870722 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.00867189 |
| ATF3 | activating transcription factor 3 | -0.00856331 |
| TMEM65 | transmembrane protein 65 | -0.00847525 |
| TFRC | transferrin receptor | -0.00844093 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0083218 |
| HMGB1 | high mobility group box 1 | -0.00830178 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.00827731 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.00826633 |
| GOLGA4 | golgin A4 | -0.00826249 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00824335 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0082254 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.00818175 |
| LRRC23 | leucine rich repeat containing 23 | -0.00817196 |
