| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0667177 |
| INTS6 | integrator complex subunit 6 | 0.0461366 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0388507 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0373788 |
| DIAPH3 | diaphanous-related formin 3 | 0.0321287 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0320205 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0314514 |
| ASPH | aspartate beta-hydroxylase | 0.0309901 |
| TLE4 | transducin-like enhancer of split 4 | 0.0307846 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0306376 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0279592 |
| CALR | calreticulin | 0.0277941 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0275902 |
| CANX | calnexin | 0.0261086 |
| SET | SET nuclear proto-oncogene | 0.0258363 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0255029 |
| PCBP2 | poly(rC) binding protein 2 | 0.0244592 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0244539 |
| SPAG9 | sperm associated antigen 9 | 0.0236309 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0235324 |
| MCL1 | myeloid cell leukemia 1 | 0.0226319 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225634 |
| ATXN1 | ataxin 1 | 0.0209545 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0209282 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0203509 |
| PKM | pyruvate kinase, muscle | 0.0202103 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0201376 |
| SMAD3 | SMAD family member 3 | 0.0199907 |
| TMEM178B | transmembrane protein 178B | 0.019946 |
| APP | amyloid beta (A4) precursor protein | 0.0197474 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0194079 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0192882 |
| TUFT1 | tuftelin 1 | 0.0186311 |
| FLNA | filamin A, alpha | 0.0184657 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0184137 |
| DIPK2A | divergent protein kinase domain 2A | 0.0181117 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0178519 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0178402 |
| COL5A1 | collagen, type V, alpha 1 | 0.0177028 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0176415 |
| PLEC | plectin | 0.0174415 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0174274 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0173009 |
| UBAP2 | ubiquitin associated protein 2 | 0.0172453 |
| PRELID2 | PRELI domain containing 2 | 0.0172412 |
| DST | dystonin | 0.0171949 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0171453 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0171048 |
| STC2 | stanniocalcin 2 | 0.0170374 |
| THBS1 | thrombospondin 1 | 0.0170086 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0164655 |
| KRT8 | keratin 8, type II | 0.0164133 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0163214 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.016229 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0161236 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0159874 |
| SFTPA2 | surfactant protein A2 | 0.0158001 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0157241 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0157215 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0156408 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0154915 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0154647 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0153989 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0152175 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0151977 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0150569 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0150283 |
| RNF213 | ring finger protein 213 | 0.0149677 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0149573 |
| LDHA | lactate dehydrogenase A | 0.0149442 |
| LIMA1 | LIM domain and actin binding 1 | 0.0148978 |
| NABP1 | nucleic acid binding protein 1 | 0.0148871 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0148217 |
| MLPH | melanophilin | 0.0147709 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0147505 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0146433 |
| PRKCA | protein kinase C, alpha | 0.0146358 |
| IGF1R | insulin-like growth factor 1 receptor | 0.014462 |
| TPM3 | tropomyosin 3 | 0.0144079 |
| SDC4 | syndecan 4 | 0.0143076 |
| FNIP1 | folliculin interacting protein 1 | 0.0139765 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0138739 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0138534 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0137798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0135368 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0133911 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0133348 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0130875 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0130141 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0129826 |
| TXNRD1 | thioredoxin reductase 1 | 0.012842 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0128362 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0128311 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0128254 |
| SQSTM1 | sequestosome 1 | 0.01269 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0126242 |
| EZR | ezrin | 0.012588 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0125691 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0125434 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0125111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.200294 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172657 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.132403 |
| MT2A | metallothionein 2A | -0.131756 |
| FN1 | fibronectin 1 | -0.123072 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0706891 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0693378 |
| CD44 | CD44 molecule (Indian blood group) | -0.0644716 |
| NDRG1 | N-myc downstream regulated 1 | -0.0590821 |
| VIM | vimentin | -0.0584708 |
| HLA-B | major histocompatibility complex, class I, B | -0.0538952 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0483249 |
| ANXA2 | annexin A2 | -0.0482851 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0466507 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.045192 |
| RAI14 | retinoic acid induced 14 | -0.0447281 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0435949 |
| ACTG1 | actin gamma 1 | -0.0405367 |
| TMSB10 | thymosin beta 10 | -0.0401859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0400322 |
| FTL | ferritin, light polypeptide | -0.0388959 |
| OSMR | oncostatin M receptor | -0.0348466 |
| RPS6 | ribosomal protein S6 | -0.0340734 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0336465 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0336234 |
| ERBIN | erbb2 interacting protein | -0.0332121 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.032849 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.031986 |
| RPL35A | ribosomal protein L35a | -0.0316708 |
| DEK | DEK proto-oncogene | -0.0314886 |
| MT1X | metallothionein 1X | -0.0306418 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0306222 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0305606 |
| ADM | adrenomedullin | -0.0301713 |
| CAVIN1 | caveolae associated protein 1 | -0.0289614 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0273222 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0270742 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0269134 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0265995 |
| TMSB4X | thymosin beta 4, X-linked | -0.0259666 |
| S100A10 | S100 calcium binding protein A10 | -0.0255078 |
| LOX | lysyl oxidase | -0.0254105 |
| GNAS | GNAS complex locus | -0.0241501 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0235591 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.023379 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0227868 |
| RPS8 | ribosomal protein S8 | -0.0224219 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0223977 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0222164 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0221217 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0217846 |
| PODXL | podocalyxin-like | -0.0211754 |
| S100A6 | S100 calcium binding protein A6 | -0.0211394 |
| HMGB1 | high mobility group box 1 | -0.0210901 |
| RPS13 | ribosomal protein S13 | -0.0203897 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0199981 |
| MMP12 | matrix metallopeptidase 12 | -0.0194079 |
| RPLP2 | ribosomal protein, large, P2 | -0.0192977 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0190545 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0190461 |
| RRBP1 | ribosome binding protein 1 | -0.0187197 |
| HLA-A | major histocompatibility complex, class I, A | -0.0185228 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0183533 |
| PGK1 | phosphoglycerate kinase 1 | -0.0179701 |
| GOLGA4 | golgin A4 | -0.0179545 |
| STK4 | serine/threonine kinase 4 | -0.0178574 |
| RPL12 | ribosomal protein L12 | -0.0177569 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0174703 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0172086 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0170715 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0169828 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0168213 |
| RPL37 | ribosomal protein L37 | -0.0165849 |
| WDR45B | WD repeat domain 45B | -0.016507 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0164307 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0163884 |
| CCND1 | cyclin D1 | -0.0161014 |
| RPS24 | ribosomal protein S24 | -0.0160962 |
| SCFD2 | sec1 family domain containing 2 | -0.0160519 |
| LMAN1 | lectin, mannose-binding, 1 | -0.015653 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0156353 |
| RPL34 | ribosomal protein L34 | -0.015609 |
| TUBB | tubulin, beta class I | -0.0154869 |
| SEPTIN7 | septin 7 | -0.0153967 |
| PFN1 | profilin 1 | -0.0153441 |
| HM13 | histocompatibility (minor) 13 | -0.0153198 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0153083 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0152374 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0152361 |
| ZFR | zinc finger RNA binding protein | -0.0151991 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.015082 |
| RPL30 | ribosomal protein L30 | -0.0150674 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.014948 |
| RPS21 | ribosomal protein S21 | -0.0148738 |
| PLIN2 | perilipin 2 | -0.014866 |
| RPL26 | ribosomal protein L26 | -0.014758 |
| NAV1 | neuron navigator 1 | -0.0147232 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0144997 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0143794 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0141461 |
