| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP58 | nucleoporin 58 | 0.0305948 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0290369 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0255394 |
| WDR43 | WD repeat domain 43 | 0.0233256 |
| SPAG9 | sperm associated antigen 9 | 0.0229319 |
| TXNRD1 | thioredoxin reductase 1 | 0.0226994 |
| KYNU | kynureninase | 0.0204456 |
| SMAD3 | SMAD family member 3 | 0.0200135 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0185867 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0183887 |
| ATP13A3 | ATPase type 13A3 | 0.0181276 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0171065 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0168979 |
| NCKAP1 | NCK-associated protein 1 | 0.0165177 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0161013 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0159068 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0151304 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0149808 |
| RPS18 | ribosomal protein S18 | 0.0148582 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0145578 |
| RBM33 | RNA binding motif protein 33 | 0.0143589 |
| RNF145 | ring finger protein 145 | 0.0142694 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0142231 |
| RBM39 | RNA binding motif protein 39 | 0.0139804 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0139172 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0138515 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0137877 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0136544 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0132996 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0132447 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0130311 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0126832 |
| APP | amyloid beta (A4) precursor protein | 0.0125807 |
| USP15 | ubiquitin specific peptidase 15 | 0.0121592 |
| POU2F1 | POU class 2 homeobox 1 | 0.0121289 |
| HELZ | helicase with zinc finger | 0.0121039 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0120873 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0120662 |
| CD109 | CD109 molecule | 0.0120235 |
| NUP153 | nucleoporin 153kDa | 0.011967 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0119614 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0119421 |
| YTHDC1 | YTH domain containing 1 | 0.0119284 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0118831 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0118813 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0118765 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0116937 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0115494 |
| RIGI | RNA sensor RIG-I | 0.0111961 |
| NBAS | neuroblastoma amplified sequence | 0.0108442 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0107373 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0106916 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0106833 |
| BRD2 | bromodomain containing 2 | 0.0106587 |
| STK17A | serine/threonine kinase 17a | 0.0105338 |
| PCBP2 | poly(rC) binding protein 2 | 0.0104426 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0102729 |
| UBE3A | ubiquitin protein ligase E3A | 0.0102152 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0101942 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0100888 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0100883 |
| MED13L | mediator complex subunit 13-like | 0.0100442 |
| MYOF | myoferlin | 0.00975518 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00972851 |
| GOLGA4 | golgin A4 | 0.00972148 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.00970648 |
| CASC3 | cancer susceptibility candidate 3 | 0.00967896 |
| ETNK1 | ethanolamine kinase 1 | 0.0096437 |
| ZNF207 | zinc finger protein 207 | 0.00964031 |
| ITGAV | integrin, alpha V | 0.00961486 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00947066 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00937668 |
| NOP58 | NOP58 ribonucleoprotein | 0.0092868 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00926748 |
| PCNX1 | pecanex 1 | 0.00920284 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.00918538 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00916717 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00915556 |
| ABI1 | abl-interactor 1 | 0.00904891 |
| SP3 | Sp3 transcription factor | 0.00904661 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00903041 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00899609 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00893762 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0089175 |
| NEK7 | NIMA-related kinase 7 | 0.00887409 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00884036 |
| CCNY | cyclin Y | 0.00882971 |
| MED13 | mediator complex subunit 13 | 0.00880043 |
| MSN | moesin | 0.00878007 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.00870362 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00868425 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00866548 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.00862959 |
| OLA1 | Obg-like ATPase 1 | 0.00860946 |
| TRIM33 | tripartite motif containing 33 | 0.00860534 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00857584 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00847934 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0084192 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0082612 |
| PPHLN1 | periphilin 1 | 0.00825595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.284015 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21445 |
| TMSB10 | thymosin beta 10 | -0.108229 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0960228 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0935751 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.092294 |
| EFNA5 | ephrin-A5 | -0.0819516 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0776856 |
| LSAMP | limbic system-associated membrane protein | -0.0776336 |
| ASPH | aspartate beta-hydroxylase | -0.07734 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0755327 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0741855 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0700696 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.068997 |
| RPS6 | ribosomal protein S6 | -0.0612501 |
| HMGA2 | high mobility group AT-hook 2 | -0.0609547 |
| KIAA1217 | KIAA1217 | -0.0581126 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0532444 |
| ACTG1 | actin gamma 1 | -0.0529168 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0516422 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0511304 |
| KIAA1549L | KIAA1549-like | -0.0510246 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0495184 |
| CDH13 | cadherin 13 | -0.0493433 |
| AHNAK | AHNAK nucleoprotein | -0.048415 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0478422 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0462354 |
| MMP12 | matrix metallopeptidase 12 | -0.0459416 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0433572 |
| MYO10 | myosin X | -0.0433456 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0428542 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0411354 |
| NAV1 | neuron navigator 1 | -0.0400635 |
| GPC6 | glypican 6 | -0.0397787 |
| MT2A | metallothionein 2A | -0.0395499 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0391236 |
| RPS3 | ribosomal protein S3 | -0.0390295 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0386122 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0371906 |
| EGR1 | early growth response 1 | -0.036809 |
| TPM4 | tropomyosin 4 | -0.0361264 |
| ANXA2 | annexin A2 | -0.0357895 |
| RPL35A | ribosomal protein L35a | -0.0348324 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0340645 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0335616 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0331378 |
| HDAC9 | histone deacetylase 9 | -0.0327341 |
| PTMA | prothymosin, alpha | -0.0324484 |
| NDRG1 | N-myc downstream regulated 1 | -0.0323043 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0321311 |
| RPLP0 | ribosomal protein, large, P0 | -0.0317907 |
| RPL23 | ribosomal protein L23 | -0.0317184 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0314474 |
| LDHA | lactate dehydrogenase A | -0.0312265 |
| RPL12 | ribosomal protein L12 | -0.0303789 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0300694 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0299905 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0296134 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0295568 |
| RPS25 | ribosomal protein S25 | -0.0287805 |
| RPS8 | ribosomal protein S8 | -0.0281073 |
| CSTB | cystatin B (stefin B) | -0.0279042 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0278189 |
| RPLP1 | ribosomal protein, large, P1 | -0.027786 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0276338 |
| DTNA | dystrobrevin, alpha | -0.0271358 |
| PGK1 | phosphoglycerate kinase 1 | -0.0271123 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0263095 |
| RPL37A | ribosomal protein L37a | -0.0261896 |
| RPS12 | ribosomal protein S12 | -0.0260637 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0259032 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0257771 |
| RACK1 | receptor for activated C kinase 1 | -0.0254651 |
| YBX3 | Y box binding protein 3 | -0.0253408 |
| RPS19 | ribosomal protein S19 | -0.0252316 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0244666 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0243984 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0242987 |
| ESM1 | endothelial cell-specific molecule 1 | -0.023802 |
| FTL | ferritin, light polypeptide | -0.0237955 |
| CDK14 | cyclin-dependent kinase 14 | -0.0236897 |
| CTSB | cathepsin B | -0.0233839 |
| RPS24 | ribosomal protein S24 | -0.0233377 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0232077 |
| RPS27A | ribosomal protein S27a | -0.0229149 |
| NABP1 | nucleic acid binding protein 1 | -0.0227485 |
| JMJD1C | jumonji domain containing 1C | -0.0225081 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0223174 |
| CALD1 | caldesmon 1 | -0.022239 |
| RPS13 | ribosomal protein S13 | -0.0221268 |
| KPNB1 | karyopherin (importin) beta 1 | -0.021785 |
| RPL30 | ribosomal protein L30 | -0.0217381 |
| SSH2 | slingshot protein phosphatase 2 | -0.0217281 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0215419 |
| CDK6 | cyclin-dependent kinase 6 | -0.0214077 |
| INTS6 | integrator complex subunit 6 | -0.02117 |
| CAVIN1 | caveolae associated protein 1 | -0.0211131 |
| ZNF804A | zinc finger protein 804A | -0.0210926 |
| RPL36 | ribosomal protein L36 | -0.0205877 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0202389 |
