| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0860319 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0802362 |
| CANX | calnexin | 0.0553531 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0518556 |
| LDHA | lactate dehydrogenase A | 0.051724 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491763 |
| EREG | epiregulin | 0.0424615 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0424566 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0396504 |
| CALR | calreticulin | 0.0355217 |
| DSPP | dentin sialophosphoprotein | 0.0346446 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0334447 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.030886 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0299923 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0297465 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0262888 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0240973 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0224596 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0219268 |
| OGA | O-GlcNAcase | 0.021022 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.020986 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0209041 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.020475 |
| GOLGA4 | golgin A4 | 0.0203968 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0200294 |
| RPS18 | ribosomal protein S18 | 0.0181847 |
| APP | amyloid beta (A4) precursor protein | 0.0180519 |
| GDF15 | growth differentiation factor 15 | 0.0180299 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0176946 |
| MLEC | malectin | 0.0175275 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0173909 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0173432 |
| FAM13A | family with sequence similarity 13, member A | 0.0171971 |
| EZR | ezrin | 0.0168851 |
| RNF43 | ring finger protein 43 | 0.0167016 |
| SCARB2 | scavenger receptor class B, member 2 | 0.016032 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.015995 |
| INSIG1 | insulin induced gene 1 | 0.0158589 |
| RBM39 | RNA binding motif protein 39 | 0.0154861 |
| CD164 | CD164 molecule, sialomucin | 0.0152431 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0152287 |
| TXNRD1 | thioredoxin reductase 1 | 0.0151514 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.014609 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0145921 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0145407 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0144942 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0139745 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0139673 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0139436 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0137448 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0137435 |
| ENO1 | enolase 1, (alpha) | 0.0136619 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0135749 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0135487 |
| SET | SET nuclear proto-oncogene | 0.0135174 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0132675 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0132353 |
| KITLG | KIT ligand | 0.0130385 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.012784 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0126363 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0125489 |
| HDLBP | high density lipoprotein binding protein | 0.012424 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0123466 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0122075 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0120574 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0120306 |
| WDR45B | WD repeat domain 45B | 0.0120113 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0119753 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0119378 |
| PRELID2 | PRELI domain containing 2 | 0.011799 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.0116366 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0115341 |
| YBX1 | Y box binding protein 1 | 0.0114787 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0114641 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0114068 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0112464 |
| RPL3 | ribosomal protein L3 | 0.0111897 |
| SHROOM3 | shroom family member 3 | 0.011092 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0110809 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0110769 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0109218 |
| TMEM59 | transmembrane protein 59 | 0.0108788 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0108236 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0107444 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0107268 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0106639 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0106134 |
| RIOK3 | RIO kinase 3 | 0.0105919 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0104267 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.010403 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0103744 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | 0.0103597 |
| XPOT | exportin, tRNA | 0.0103371 |
| COPA | coatomer protein complex, subunit alpha | 0.0102881 |
| EPCAM | epithelial cell adhesion molecule | 0.0102543 |
| PHF3 | PHD finger protein 3 | 0.0101643 |
| CCDC47 | coiled-coil domain containing 47 | 0.0101561 |
| S100P | S100 calcium binding protein P | 0.0100977 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0100756 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0100249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.169519 |
| TMSB10 | thymosin beta 10 | -0.16023 |
| PTMA | prothymosin, alpha | -0.110561 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.103568 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0839391 |
| RPS6 | ribosomal protein S6 | -0.0827228 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0707446 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0620173 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0597209 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0587017 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0586427 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0566819 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0562103 |
| ACTG1 | actin gamma 1 | -0.0553895 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0543878 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.053193 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0524735 |
| MYO1E | myosin IE | -0.0449556 |
| RPL34 | ribosomal protein L34 | -0.0400962 |
| RPL35A | ribosomal protein L35a | -0.0397831 |
| CALB1 | calbindin 1, 28kDa | -0.0379851 |
| S100A6 | S100 calcium binding protein A6 | -0.0376659 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0375948 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0370411 |
| RPS8 | ribosomal protein S8 | -0.0370141 |
| RNF217 | ring finger protein 217 | -0.0350483 |
| FLNB | filamin B, beta | -0.0348187 |
| RPL9 | ribosomal protein L9 | -0.0344684 |
| TFF1 | trefoil factor 1 | -0.0336818 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0326421 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0322802 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0299259 |
| POTEF | POTE ankyrin domain family, member F | -0.0296359 |
| ONECUT3 | one cut homeobox 3 | -0.0292883 |
| PARD3 | par-3 family cell polarity regulator | -0.0290654 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0289832 |
| RPS21 | ribosomal protein S21 | -0.0284187 |
| TFF3 | trefoil factor 3 (intestinal) | -0.028161 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0279866 |
| RPS19 | ribosomal protein S19 | -0.0278214 |
| RPLP2 | ribosomal protein, large, P2 | -0.0277841 |
| SH3D19 | SH3 domain containing 19 | -0.0276585 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0275423 |
| RPS25 | ribosomal protein S25 | -0.0268294 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0261593 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0260694 |
| MT2A | metallothionein 2A | -0.0259451 |
| EGFR | epidermal growth factor receptor | -0.0258212 |
| RPL37A | ribosomal protein L37a | -0.0257849 |
| FHIT | fragile histidine triad | -0.0253069 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0250244 |
| HMGA1 | high mobility group AT-hook 1 | -0.0247521 |
| DIAPH2 | diaphanous-related formin 2 | -0.0239249 |
| RPL8 | ribosomal protein L8 | -0.0233447 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0230913 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0223835 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0222629 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0220557 |
| MED13 | mediator complex subunit 13 | -0.0218939 |
| HMGB1 | high mobility group box 1 | -0.0215335 |
| RPS23 | ribosomal protein S23 | -0.0213041 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0210394 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0209299 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0208271 |
| CUX1 | cut-like homeobox 1 | -0.0207658 |
| RPS29 | ribosomal protein S29 | -0.0206705 |
| SVIL | supervillin | -0.020649 |
| FRMD5 | FERM domain containing 5 | -0.020492 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0204736 |
| JMJD1C | jumonji domain containing 1C | -0.0202139 |
| RPL23 | ribosomal protein L23 | -0.0201747 |
| KLK10 | kallikrein-related peptidase 10 | -0.0201396 |
| TPM4 | tropomyosin 4 | -0.0199565 |
| RIN2 | Ras and Rab interactor 2 | -0.0199281 |
| FOXO1 | forkhead box O1 | -0.0198792 |
| RPS12 | ribosomal protein S12 | -0.019865 |
| FERMT1 | fermitin family member 1 | -0.0197966 |
| PRSS3 | protease, serine, 3 | -0.0196516 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0192027 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0190013 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0188604 |
| RPLP1 | ribosomal protein, large, P1 | -0.0185151 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0183177 |
| MUC17 | mucin 17, cell surface associated | -0.0182324 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0181295 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0179137 |
| LSAMP | limbic system-associated membrane protein | -0.0177866 |
| RPS14 | ribosomal protein S14 | -0.0176635 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0174237 |
| PFN1 | profilin 1 | -0.0173755 |
| CLOCK | clock circadian regulator | -0.0173632 |
| RPS24 | ribosomal protein S24 | -0.0172768 |
| RAD51B | RAD51 paralog B | -0.0172289 |
| RAB10 | RAB10, member RAS oncogene family | -0.0172153 |
| SMYD3 | SET and MYND domain containing 3 | -0.0171899 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0166871 |
| DIAPH1 | diaphanous-related formin 1 | -0.0166604 |
| LAMA4 | laminin, alpha 4 | -0.0165903 |
| S100A10 | S100 calcium binding protein A10 | -0.0165712 |
| ABHD2 | abhydrolase domain containing 2 | -0.0165445 |
