| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.195456 |
| PCBP2 | poly(rC) binding protein 2 | 0.1353 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.120957 |
| FNDC3B | fibronectin type III domain containing 3B | 0.107492 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.102552 |
| CD44 | CD44 molecule (Indian blood group) | 0.100365 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0838171 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0778412 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0714367 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.07031 |
| SMAD3 | SMAD family member 3 | 0.0702505 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0694177 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0661189 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0634397 |
| TGM2 | transglutaminase 2 | 0.0615066 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.061176 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0608547 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0586109 |
| VMP1 | vacuole membrane protein 1 | 0.0535141 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0505693 |
| MCL1 | myeloid cell leukemia 1 | 0.0499518 |
| USP34 | ubiquitin specific peptidase 34 | 0.048226 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0474304 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0448081 |
| EGFR | epidermal growth factor receptor | 0.0427516 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0418465 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0398482 |
| EFNA5 | ephrin-A5 | 0.0389658 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.037806 |
| COG5 | component of oligomeric golgi complex 5 | 0.0377388 |
| NAV2 | neuron navigator 2 | 0.0363713 |
| RBM39 | RNA binding motif protein 39 | 0.0363142 |
| VEGFA | vascular endothelial growth factor A | 0.0360442 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0357859 |
| GOLGA4 | golgin A4 | 0.0352062 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0350234 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0345926 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.033473 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0327538 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0326782 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.032614 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0320973 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0316362 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0314401 |
| SEC24A | SEC24 family member A | 0.0312649 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0312535 |
| SPAG9 | sperm associated antigen 9 | 0.0311647 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0310762 |
| KYNU | kynureninase | 0.0305597 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0299461 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0297927 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0295815 |
| MSN | moesin | 0.0294058 |
| SIK3 | SIK family kinase 3 | 0.0293808 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0293098 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0292954 |
| FAM107B | family with sequence similarity 107, member B | 0.0289903 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0288696 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0286927 |
| MYO1E | myosin IE | 0.0282387 |
| GPHN | gephyrin | 0.0280657 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0279462 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0276621 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0275198 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0272071 |
| ARF4 | ADP-ribosylation factor 4 | 0.0269809 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0269399 |
| RNF19B | ring finger protein 19B | 0.0269022 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.025947 |
| FRMD4A | FERM domain containing 4A | 0.0257337 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0256466 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.025605 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0255151 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0252733 |
| KSR1 | kinase suppressor of ras 1 | 0.0252557 |
| COPA | coatomer protein complex, subunit alpha | 0.0252096 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0250425 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0249192 |
| APP | amyloid beta (A4) precursor protein | 0.0248088 |
| MYO1B | myosin IB | 0.0245095 |
| CCNL1 | cyclin L1 | 0.0244179 |
| YBX1 | Y box binding protein 1 | 0.0242527 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0241944 |
| KIF5B | kinesin family member 5B | 0.0240858 |
| HAS2 | hyaluronan synthase 2 | 0.0238109 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0236723 |
| ECE1 | endothelin converting enzyme 1 | 0.0234194 |
| PTEN | phosphatase and tensin homolog | 0.0232683 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0232322 |
| SMAD4 | SMAD family member 4 | 0.0231422 |
| CANX | calnexin | 0.0227168 |
| ATP13A3 | ATPase type 13A3 | 0.0227019 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0225545 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0225024 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0224819 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0222753 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0222362 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0220936 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0220271 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0219014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.154733 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.136715 |
| TMSB10 | thymosin beta 10 | -0.132339 |
| GLCCI1 | glucocorticoid induced 1 | -0.086424 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0726691 |
| HMGA2 | high mobility group AT-hook 2 | -0.0721732 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0710129 |
| MEF2A | myocyte enhancer factor 2A | -0.0671042 |
| CDH13 | cadherin 13 | -0.0645766 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0623045 |
| VIM | vimentin | -0.0622002 |
| S100A6 | S100 calcium binding protein A6 | -0.0602119 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0554194 |
| MTSS1 | metastasis suppressor 1 | -0.0553134 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0509442 |
| RAI14 | retinoic acid induced 14 | -0.0474317 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0450321 |
| STC1 | stanniocalcin 1 | -0.0420217 |
| DST | dystonin | -0.0407265 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0378038 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.037589 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0369321 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0361704 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036112 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0360838 |
| MECOM | MDS1 and EVI1 complex locus | -0.0349964 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0344219 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0341635 |
| H1-0 | H1.0 linker histone | -0.0335973 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0330009 |
| BMERB1 | bMERB domain containing 1 | -0.0329457 |
| NRG1 | neuregulin 1 | -0.0323836 |
| ENOSF1 | enolase superfamily member 1 | -0.0318051 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0315024 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0312021 |
| NTN4 | netrin 4 | -0.0307637 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0306371 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0305248 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.030168 |
| NRP1 | neuropilin 1 | -0.0300372 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0293107 |
| TMSB4X | thymosin beta 4, X-linked | -0.0287032 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0281041 |
| FAM20C | family with sequence similarity 20, member C | -0.028036 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0274016 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0266579 |
| S100A10 | S100 calcium binding protein A10 | -0.0266276 |
| PYGL | phosphorylase, glycogen, liver | -0.0265786 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0263103 |
| RPL37A | ribosomal protein L37a | -0.0262995 |
| CLMP | CXADR-like membrane protein | -0.0261898 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0260927 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0259406 |
| COL7A1 | collagen, type VII, alpha 1 | -0.025754 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0256373 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.025286 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0251876 |
| FTL | ferritin, light polypeptide | -0.0251289 |
| RPS19 | ribosomal protein S19 | -0.0248994 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0247603 |
| LOX | lysyl oxidase | -0.0246937 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0246605 |
| NAV1 | neuron navigator 1 | -0.0245853 |
| CDK14 | cyclin-dependent kinase 14 | -0.0239154 |
| TGFB1 | transforming growth factor, beta 1 | -0.0239013 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0236699 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0234012 |
| IFI44L | interferon-induced protein 44-like | -0.0231227 |
| AHNAK | AHNAK nucleoprotein | -0.0230037 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0229625 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0226506 |
| SUMF1 | sulfatase modifying factor 1 | -0.0224021 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0223766 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0220794 |
| PRSS23 | protease, serine, 23 | -0.0220254 |
| CUX1 | cut-like homeobox 1 | -0.0220068 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0215359 |
| RPLP1 | ribosomal protein, large, P1 | -0.0212862 |
| OXR1 | oxidation resistance 1 | -0.0211981 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0211273 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.0208635 |
| RPL34 | ribosomal protein L34 | -0.020775 |
| RGS17 | regulator of G-protein signaling 17 | -0.020666 |
| SP100 | SP100 nuclear antigen | -0.0206378 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0204985 |
| ZNF804A | zinc finger protein 804A | -0.0204783 |
| DTNA | dystrobrevin, alpha | -0.0204592 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0204294 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0204084 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0202124 |
| HLA-B | major histocompatibility complex, class I, B | -0.0202112 |
| PTMA | prothymosin, alpha | -0.020008 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0200006 |
| GNAS | GNAS complex locus | -0.0199754 |
| PCNX4 | pecanex 4 | -0.0199673 |
| ANXA10 | annexin A10 | -0.0198294 |
| TMOD1 | tropomodulin 1 | -0.0198271 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0196741 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0196001 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0194981 |
