| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0968173 |
| CANX | calnexin | 0.0446617 |
| LDHA | lactate dehydrogenase A | 0.0437876 |
| SMAD3 | SMAD family member 3 | 0.0414596 |
| KRT17 | keratin 17, type I | 0.0391658 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0344434 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0338115 |
| INTS6 | integrator complex subunit 6 | 0.0332866 |
| AHNAK | AHNAK nucleoprotein | 0.0319816 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.028261 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0278251 |
| EZR | ezrin | 0.0267864 |
| RPS18 | ribosomal protein S18 | 0.0265605 |
| DSPP | dentin sialophosphoprotein | 0.0259326 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0250509 |
| PLEC | plectin | 0.0246293 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0242246 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0241646 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0230002 |
| MCL1 | myeloid cell leukemia 1 | 0.0225683 |
| MX1 | MX dynamin-like GTPase 1 | 0.0220254 |
| SEPTIN9 | septin 9 | 0.021703 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.021179 |
| APP | amyloid beta (A4) precursor protein | 0.0210976 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0209075 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0205497 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0203162 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0197487 |
| ASPH | aspartate beta-hydroxylase | 0.0195743 |
| MUC16 | mucin 16, cell surface associated | 0.0194769 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0193755 |
| RNF213 | ring finger protein 213 | 0.0193397 |
| LMO7 | LIM domain 7 | 0.0186437 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0179411 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0171371 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0170378 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0167411 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0165177 |
| GOLGB1 | golgin B1 | 0.0164737 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0164457 |
| EXOC4 | exocyst complex component 4 | 0.0163117 |
| EGFR | epidermal growth factor receptor | 0.0162343 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.016057 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0160548 |
| HDAC9 | histone deacetylase 9 | 0.0159797 |
| TGM2 | transglutaminase 2 | 0.0159541 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0159086 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0157345 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0156683 |
| EFNA5 | ephrin-A5 | 0.0155146 |
| MYEOV | myeloma overexpressed | 0.0154423 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0153654 |
| SDC4 | syndecan 4 | 0.0151866 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0151754 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.015161 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0149709 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0149129 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0148635 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0148629 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0148149 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0147949 |
| FAM107B | family with sequence similarity 107, member B | 0.0145954 |
| ATXN1 | ataxin 1 | 0.0144667 |
| PKM | pyruvate kinase, muscle | 0.0144455 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0144065 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0143308 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0143175 |
| SVIL | supervillin | 0.0142669 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0140737 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0140327 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.013946 |
| EHF | ets homologous factor | 0.0136415 |
| C3 | complement component 3 | 0.0134006 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0129744 |
| TPM4 | tropomyosin 4 | 0.0128852 |
| RAD51B | RAD51 paralog B | 0.0128557 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0126673 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0124882 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0124717 |
| SET | SET nuclear proto-oncogene | 0.012381 |
| FOXP1 | forkhead box P1 | 0.0123778 |
| AEBP2 | AE binding protein 2 | 0.0123348 |
| DAPK1 | death-associated protein kinase 1 | 0.0122546 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0121916 |
| NRDC | nardilysin convertase | 0.0121457 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0120938 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0120542 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0119336 |
| CALR | calreticulin | 0.0118896 |
| PLK2 | polo-like kinase 2 | 0.0116629 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.011657 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0116476 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0114591 |
| H2BC5 | H2B clustered histone 5 | 0.0114466 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0114139 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0113746 |
| CLIC4 | chloride intracellular channel 4 | 0.0113506 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0113492 |
| FN1 | fibronectin 1 | 0.0111602 |
| LAMC2 | laminin, gamma 2 | 0.0111436 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205437 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.13776 |
| TMSB10 | thymosin beta 10 | -0.115965 |
| PTMA | prothymosin, alpha | -0.092688 |
| RPL35A | ribosomal protein L35a | -0.0628953 |
| RPS6 | ribosomal protein S6 | -0.060919 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0579368 |
| HMGA1 | high mobility group AT-hook 1 | -0.0565986 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0537301 |
| TSC22D2 | TSC22 domain family, member 2 | -0.052166 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0504392 |
| FAM3C | family with sequence similarity 3, member C | -0.0468795 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0466788 |
| RPL34 | ribosomal protein L34 | -0.0461791 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0453836 |
| MT2A | metallothionein 2A | -0.0439881 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0428637 |
| RPS21 | ribosomal protein S21 | -0.0421597 |
| OGA | O-GlcNAcase | -0.0421257 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0414608 |
| GOLGA4 | golgin A4 | -0.0404517 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0399678 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0398475 |
| RBM25 | RNA binding motif protein 25 | -0.0391994 |
| RPLP1 | ribosomal protein, large, P1 | -0.036832 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0368204 |
| JMJD1C | jumonji domain containing 1C | -0.036382 |
| RPS8 | ribosomal protein S8 | -0.0360407 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0354768 |
| TMSB4X | thymosin beta 4, X-linked | -0.0354412 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0347761 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0343777 |
| RPS19 | ribosomal protein S19 | -0.0342138 |
| RPL23 | ribosomal protein L23 | -0.0339697 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0339033 |
| RBM39 | RNA binding motif protein 39 | -0.0338247 |
| RPS13 | ribosomal protein S13 | -0.0333751 |
| MYO6 | myosin VI | -0.0331225 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0310821 |
| LAMA4 | laminin, alpha 4 | -0.0310638 |
| SPAG9 | sperm associated antigen 9 | -0.0305157 |
| S100A6 | S100 calcium binding protein A6 | -0.0299426 |
| RPS24 | ribosomal protein S24 | -0.0299316 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0295548 |
| GNAS | GNAS complex locus | -0.0292859 |
| CD2AP | CD2-associated protein | -0.0288381 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0284229 |
| FRMD5 | FERM domain containing 5 | -0.0284216 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0283736 |
| H3-3B | H3.3 histone B | -0.0282051 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0280505 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0280142 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0279708 |
| RPL32 | ribosomal protein L32 | -0.0279377 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0276891 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0273985 |
| H1-0 | H1.0 linker histone | -0.0272856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0271347 |
| RPS29 | ribosomal protein S29 | -0.0269332 |
| RPL28 | ribosomal protein L28 | -0.0264828 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0261636 |
| RPL37A | ribosomal protein L37a | -0.0261022 |
| B2M | beta-2-microglobulin | -0.0260486 |
| MEF2A | myocyte enhancer factor 2A | -0.0257649 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0252975 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0252232 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0250359 |
| RIOK3 | RIO kinase 3 | -0.0249584 |
| TPI1 | triosephosphate isomerase 1 | -0.0245205 |
| RPL36A | ribosomal protein L36a | -0.0244626 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.024156 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0241039 |
| RPS25 | ribosomal protein S25 | -0.0240422 |
| RPL19 | ribosomal protein L19 | -0.0239341 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0239324 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0235335 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0233402 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0231723 |
| HLA-B | major histocompatibility complex, class I, B | -0.0231697 |
| PLAU | plasminogen activator, urokinase | -0.022859 |
| G0S2 | G0/G1 switch 2 | -0.0224695 |
| RPS3 | ribosomal protein S3 | -0.0221531 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.022095 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0220144 |
| RPL26 | ribosomal protein L26 | -0.0219585 |
| ZNF292 | zinc finger protein 292 | -0.0218952 |
| FTL | ferritin, light polypeptide | -0.0218391 |
| RPL8 | ribosomal protein L8 | -0.0218159 |
| S100A9 | S100 calcium binding protein A9 | -0.0218101 |
| RLF | rearranged L-myc fusion | -0.0215811 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0215454 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0214914 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0214538 |
| PARD3 | par-3 family cell polarity regulator | -0.0214206 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0210897 |
| RPS5 | ribosomal protein S5 | -0.0210133 |
| NDRG1 | N-myc downstream regulated 1 | -0.020765 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0205255 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0204153 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0204089 |
