| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.25725 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0728996 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0710206 |
| NDRG1 | N-myc downstream regulated 1 | 0.0700812 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.069962 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0667553 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0604182 |
| TGM2 | transglutaminase 2 | 0.0508393 |
| PKM | pyruvate kinase, muscle | 0.050243 |
| POTEF | POTE ankyrin domain family, member F | 0.0500127 |
| LDHA | lactate dehydrogenase A | 0.0497954 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0486505 |
| CD44 | CD44 molecule (Indian blood group) | 0.0485955 |
| CLIC4 | chloride intracellular channel 4 | 0.0483799 |
| MSN | moesin | 0.0480821 |
| ASPH | aspartate beta-hydroxylase | 0.0461541 |
| PGK1 | phosphoglycerate kinase 1 | 0.0451307 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0446752 |
| MCL1 | myeloid cell leukemia 1 | 0.0444208 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0438954 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0418262 |
| CENPF | centromere protein F, 350/400kDa | 0.0406083 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0405318 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0404316 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.040218 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0399928 |
| VEGFA | vascular endothelial growth factor A | 0.039639 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0390707 |
| THBS1 | thrombospondin 1 | 0.0384909 |
| AFAP1 | actin filament associated protein 1 | 0.0383655 |
| STC1 | stanniocalcin 1 | 0.0383053 |
| NRP1 | neuropilin 1 | 0.0368197 |
| ENO1 | enolase 1, (alpha) | 0.035859 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0352874 |
| TXNRD1 | thioredoxin reductase 1 | 0.035026 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0344726 |
| YEATS2 | YEATS domain containing 2 | 0.0342328 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.033991 |
| FAM20C | family with sequence similarity 20, member C | 0.033742 |
| CCNL1 | cyclin L1 | 0.0329775 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0329719 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0328119 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0323288 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0322321 |
| PCBP2 | poly(rC) binding protein 2 | 0.032199 |
| MYO1B | myosin IB | 0.0321624 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0314163 |
| CDK19 | cyclin-dependent kinase 19 | 0.0312363 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0305221 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0302098 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0290676 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0284634 |
| SETD5 | SET domain containing 5 | 0.027492 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.026327 |
| COPA | coatomer protein complex, subunit alpha | 0.0261621 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0259758 |
| DIAPH3 | diaphanous-related formin 3 | 0.0258272 |
| RTN4 | reticulon 4 | 0.0257956 |
| VMP1 | vacuole membrane protein 1 | 0.0256589 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.025622 |
| NUP58 | nucleoporin 58 | 0.0253873 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0252799 |
| ZNF638 | zinc finger protein 638 | 0.0250638 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248005 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0239753 |
| NF1 | neurofibromin 1 | 0.0237939 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0236623 |
| NBEAL1 | neurobeachin-like 1 | 0.0235842 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0235579 |
| COL5A1 | collagen, type V, alpha 1 | 0.0233242 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0230477 |
| SDC4 | syndecan 4 | 0.0227771 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0225552 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0223864 |
| ZNF148 | zinc finger protein 148 | 0.0221093 |
| PTK2 | protein tyrosine kinase 2 | 0.0219768 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0219665 |
| LIMD1 | LIM domains containing 1 | 0.0219442 |
| PLEC | plectin | 0.0219113 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0215056 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0214021 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0212001 |
| INSIG2 | insulin induced gene 2 | 0.0211091 |
| TMF1 | TATA element modulatory factor 1 | 0.0207355 |
| PCM1 | pericentriolar material 1 | 0.0206779 |
| XPO1 | exportin 1 | 0.0205308 |
| ARRDC3 | arrestin domain containing 3 | 0.0205048 |
| C1D | C1D nuclear receptor corepressor | 0.0200529 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0200151 |
| CANX | calnexin | 0.0199396 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0198231 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0196012 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0195632 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0194972 |
| TP63 | tumor protein p63 | 0.0194963 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0194515 |
| MYADM | myeloid-associated differentiation marker | 0.0194351 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0192654 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0190774 |
| PHF21A | PHD finger protein 21A | 0.0189259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16156 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109382 |
| CDH13 | cadherin 13 | -0.0926716 |
| HLA-B | major histocompatibility complex, class I, B | -0.0838665 |
| NAV1 | neuron navigator 1 | -0.0754586 |
| VIM | vimentin | -0.0657996 |
| B2M | beta-2-microglobulin | -0.0657116 |
| COL1A1 | collagen, type I, alpha 1 | -0.061294 |
| FRMD4A | FERM domain containing 4A | -0.0609607 |
| LOXL2 | lysyl oxidase-like 2 | -0.0584708 |
| ANXA2 | annexin A2 | -0.0574075 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0572584 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0565555 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0564836 |
| SP100 | SP100 nuclear antigen | -0.0519082 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0517293 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.046585 |
| FTL | ferritin, light polypeptide | -0.045961 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0459011 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.044895 |
| CADM1 | cell adhesion molecule 1 | -0.0444381 |
| TMEM178B | transmembrane protein 178B | -0.0436546 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0401694 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0385674 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0376832 |
| H1-0 | H1.0 linker histone | -0.0371422 |
| HDAC9 | histone deacetylase 9 | -0.0368163 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0361068 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0357073 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0355043 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0351616 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0351375 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0345722 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0338407 |
| SQSTM1 | sequestosome 1 | -0.0337228 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0336912 |
| TMSB10 | thymosin beta 10 | -0.0324712 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.032451 |
| S100A10 | S100 calcium binding protein A10 | -0.0312752 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0309425 |
| HLA-E | major histocompatibility complex, class I, E | -0.0305799 |
| RPL35A | ribosomal protein L35a | -0.0301035 |
| HLA-A | major histocompatibility complex, class I, A | -0.0300174 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299301 |
| INHBA | inhibin, beta A | -0.0298507 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0295682 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0292025 |
| RPS8 | ribosomal protein S8 | -0.0291547 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0287047 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0286805 |
| IER3 | immediate early response 3 | -0.028457 |
| TNNC1 | troponin C type 1 (slow) | -0.0283709 |
| HLA-C | major histocompatibility complex, class I, C | -0.0282019 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0276889 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0276453 |
| XAF1 | XIAP associated factor 1 | -0.0275558 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0275461 |
| RPL23 | ribosomal protein L23 | -0.027342 |
| HMGB1 | high mobility group box 1 | -0.0270262 |
| TGFB1 | transforming growth factor, beta 1 | -0.0264691 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0261996 |
| RIGI | RNA sensor RIG-I | -0.0258781 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.025843 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0257221 |
| ACTG1 | actin gamma 1 | -0.0255999 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0254802 |
| RPL11 | ribosomal protein L11 | -0.0251733 |
| CAVIN1 | caveolae associated protein 1 | -0.0251522 |
| RPL26 | ribosomal protein L26 | -0.0250616 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0241722 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0241104 |
| RPS6 | ribosomal protein S6 | -0.0240379 |
| SMAD3 | SMAD family member 3 | -0.0238397 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.023246 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0230904 |
| FHIT | fragile histidine triad | -0.023082 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0228803 |
| ADM | adrenomedullin | -0.0226909 |
| IL1B | interleukin 1, beta | -0.0225976 |
| COL5A3 | collagen, type V, alpha 3 | -0.0224278 |
| CCDC138 | coiled-coil domain containing 138 | -0.0223476 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0221429 |
| RPS25 | ribosomal protein S25 | -0.0220161 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0216653 |
| RPL28 | ribosomal protein L28 | -0.021374 |
| RPL34 | ribosomal protein L34 | -0.0213616 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0211195 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0210102 |
| MT2A | metallothionein 2A | -0.0209726 |
| GLIS3 | GLIS family zinc finger 3 | -0.0207099 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0205058 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0202433 |
| NABP1 | nucleic acid binding protein 1 | -0.020194 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0199557 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0198486 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0197525 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0193384 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0193097 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0189506 |
