| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.163646 |
| PDE10A | phosphodiesterase 10A | 0.141751 |
| VGF | VGF nerve growth factor inducible | 0.138878 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0952407 |
| SNTG1 | syntrophin, gamma 1 | 0.0904272 |
| SMYD3 | SET and MYND domain containing 3 | 0.0797705 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0784705 |
| NRG1 | neuregulin 1 | 0.0650139 |
| TXNRD1 | thioredoxin reductase 1 | 0.0641169 |
| CNKSR3 | CNKSR family member 3 | 0.0634302 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.060125 |
| WWOX | WW domain containing oxidoreductase | 0.058352 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0575919 |
| MCL1 | myeloid cell leukemia 1 | 0.0574369 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | 0.0567205 |
| RNF213 | ring finger protein 213 | 0.0539557 |
| RIT2 | Ras-like without CAAX 2 | 0.0511377 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0510022 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0508877 |
| NBEA | neurobeachin | 0.0504227 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0492063 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0486485 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0475684 |
| SLC35F4 | solute carrier family 35, member F4 | 0.0469367 |
| AUTS2 | autism susceptibility candidate 2 | 0.0468946 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0465152 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0458535 |
| FGF14 | fibroblast growth factor 14 | 0.0443642 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0439073 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0437224 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.0428315 |
| PEX5L | peroxisomal biogenesis factor 5-like | 0.0425851 |
| AOPEP | aminopeptidase O (putative) | 0.0424281 |
| NCKAP5 | NCK-associated protein 5 | 0.0418454 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0414515 |
| LSAMP | limbic system-associated membrane protein | 0.0414064 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.04106 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0404505 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0403793 |
| GPC6 | glypican 6 | 0.0399213 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0398651 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0397417 |
| TOX | thymocyte selection-associated high mobility group box | 0.0396735 |
| SYT1 | synaptotagmin I | 0.0395911 |
| GSE1 | Gse1 coiled-coil protein | 0.0394937 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.039163 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0391081 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0384503 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0383291 |
| TENM1 | teneurin transmembrane protein 1 | 0.0380784 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 | 0.0379502 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0368133 |
| CANX | calnexin | 0.0366586 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0360312 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0358788 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0348687 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0346754 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0342229 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0342212 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0341564 |
| EGR1 | early growth response 1 | 0.033978 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0339047 |
| PCDH9 | protocadherin 9 | 0.0334496 |
| PHF14 | PHD finger protein 14 | 0.0332825 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0330612 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0329729 |
| PRKD1 | protein kinase D1 | 0.0329433 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0328718 |
| DGKB | diacylglycerol kinase, beta 90kDa | 0.032812 |
| GPC5 | glypican 5 | 0.0326283 |
| FTL | ferritin, light polypeptide | 0.0325919 |
| JAZF1 | JAZF zinc finger 1 | 0.0324519 |
| PTMA | prothymosin, alpha | 0.0323654 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0317516 |
| INHBA | inhibin, beta A | 0.0315326 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0313582 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0313217 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0312487 |
| RALYL | RALY RNA binding protein-like | 0.0311047 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0301408 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.029818 |
| MAP1B | microtubule-associated protein 1B | 0.0293125 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.028585 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.028506 |
| DST | dystonin | 0.0282251 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0281824 |
| FHIT | fragile histidine triad | 0.0280293 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.028029 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0276611 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0272775 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0271206 |
| PTK2 | protein tyrosine kinase 2 | 0.0270785 |
| SCFD2 | sec1 family domain containing 2 | 0.0267568 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 0.0266449 |
| CNTNAP2 | contactin associated protein-like 2 | 0.02654 |
| KCTD8 | potassium channel tetramerization domain containing 8 | 0.0265141 |
| ZNF804A | zinc finger protein 804A | 0.0264033 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0261589 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | 0.0259254 |
| TMEM178B | transmembrane protein 178B | 0.0253253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.103878 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0699491 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0660864 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0590513 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0586759 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0479069 |
| CENPF | centromere protein F, 350/400kDa | -0.0477608 |
| FAM13A | family with sequence similarity 13, member A | -0.0475438 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0474604 |
| STC1 | stanniocalcin 1 | -0.0403085 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0390503 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0364744 |
| ZNF292 | zinc finger protein 292 | -0.0358583 |
| RPS2 | ribosomal protein S2 | -0.0355338 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0347972 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0343026 |
| PGK1 | phosphoglycerate kinase 1 | -0.0337427 |
| JAM3 | junctional adhesion molecule 3 | -0.0302995 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0295653 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.029496 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0292724 |
| ZNF395 | zinc finger protein 395 | -0.0292316 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0283818 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0278967 |
| AURKA | aurora kinase A | -0.0278345 |
| WDR45B | WD repeat domain 45B | -0.0271021 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0270722 |
| FAM162A | family with sequence similarity 162, member A | -0.0267538 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0263831 |
| RPL37A | ribosomal protein L37a | -0.0263192 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0259912 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0259447 |
| CA8 | carbonic anhydrase VIII | -0.0254847 |
| RLF | rearranged L-myc fusion | -0.0254676 |
| NUP58 | nucleoporin 58 | -0.0253106 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.024898 |
| TPX2 | TPX2, microtubule-associated | -0.0246348 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0238351 |
| VEGFA | vascular endothelial growth factor A | -0.0236251 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0234419 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0233767 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0232471 |
| DTNA | dystrobrevin, alpha | -0.0232088 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0230213 |
| ENO1 | enolase 1, (alpha) | -0.0228249 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.0227891 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0224177 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0223842 |
| XPO1 | exportin 1 | -0.0216331 |
| CABIN1 | calcineurin binding protein 1 | -0.0215635 |
| RPS6 | ribosomal protein S6 | -0.021422 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0208198 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0208112 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.020767 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0206472 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0205439 |
| MALT1 | MALT1 paracaspase | -0.0200229 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0193269 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -0.0191332 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0191221 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0185269 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0182402 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0182401 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0181729 |
| RAB40C | RAB40C, member RAS oncogene family | -0.0179038 |
| GLG1 | golgi glycoprotein 1 | -0.0178839 |
| CCNY | cyclin Y | -0.0176448 |
| RNF24 | ring finger protein 24 | -0.0171865 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0171498 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0170404 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0170162 |
| RPS25 | ribosomal protein S25 | -0.0170137 |
| PPDPFL | pancreatic progenitor cell differentiation and proliferation factor like | -0.0170017 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0169832 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0168268 |
| CDON | cell adhesion associated, oncogene regulated | -0.0163459 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0162861 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0161792 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0161265 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.016089 |
| SPAG5 | sperm associated antigen 5 | -0.0159472 |
| KIF2C | kinesin family member 2C | -0.0159118 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0157332 |
| CCDC88A | coiled-coil domain containing 88A | -0.0156843 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0156617 |
| NGLY1 | N-glycanase 1 | -0.0153795 |
| PDE7A | phosphodiesterase 7A | -0.0153781 |
| ATRN | attractin | -0.0153756 |
| H1-4 | H1.4 linker histone, cluster member | -0.0153433 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0153382 |
| GOLGA4 | golgin A4 | -0.0153034 |
| RPS12 | ribosomal protein S12 | -0.0152834 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0152783 |
| DENND1A | DENN/MADD domain containing 1A | -0.0152563 |
| MICU2 | mitochondrial calcium uptake 2 | -0.0151678 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0151109 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0151086 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | -0.0150939 |
| NKTR | natural killer cell triggering receptor | -0.0150729 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0150681 |
