| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bestatin (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0848776 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0648027 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0474029 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0448285 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0445786 |
| SFTPA2 | surfactant protein A2 | 0.0432814 |
| FN1 | fibronectin 1 | 0.0378813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0364412 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.036238 |
| APP | amyloid beta (A4) precursor protein | 0.0323174 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0286302 |
| AHNAK | AHNAK nucleoprotein | 0.0279466 |
| CANX | calnexin | 0.0277319 |
| SDC4 | syndecan 4 | 0.0271818 |
| MLPH | melanophilin | 0.0267705 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0265674 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0228405 |
| HLA-B | major histocompatibility complex, class I, B | 0.022468 |
| MCL1 | myeloid cell leukemia 1 | 0.0216306 |
| FAM20C | family with sequence similarity 20, member C | 0.020101 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0197936 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0188999 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0187879 |
| ASPH | aspartate beta-hydroxylase | 0.0182698 |
| HDAC9 | histone deacetylase 9 | 0.0169637 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0165578 |
| TMSB4X | thymosin beta 4, X-linked | 0.0164865 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0158979 |
| ARRDC3 | arrestin domain containing 3 | 0.0157037 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0152401 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0151478 |
| RIGI | RNA sensor RIG-I | 0.0150594 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0141981 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0141068 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0139692 |
| MX1 | MX dynamin-like GTPase 1 | 0.0139084 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0137059 |
| STC2 | stanniocalcin 2 | 0.0133841 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0132232 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.01309 |
| VCL | vinculin | 0.0129342 |
| MSN | moesin | 0.0128248 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0128158 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0127383 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0126838 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0122011 |
| NCOA7 | nuclear receptor coactivator 7 | 0.012127 |
| PHF3 | PHD finger protein 3 | 0.0118004 |
| TPM4 | tropomyosin 4 | 0.0117768 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0117139 |
| IPO7 | importin 7 | 0.0115787 |
| FMN1 | formin 1 | 0.0115743 |
| VEGFA | vascular endothelial growth factor A | 0.0115462 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0114034 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0112459 |
| FBXO32 | F-box protein 32 | 0.0110286 |
| SP100 | SP100 nuclear antigen | 0.0108997 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0108555 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0107909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0107865 |
| EZR | ezrin | 0.0107422 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0107095 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.01067 |
| SERINC1 | serine incorporator 1 | 0.0103792 |
| RRBP1 | ribosome binding protein 1 | 0.0102758 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0101175 |
| ENO1 | enolase 1, (alpha) | 0.0101033 |
| HLA-C | major histocompatibility complex, class I, C | 0.00997167 |
| SQSTM1 | sequestosome 1 | 0.00995271 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00992571 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.00980417 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00970476 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00969999 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00958022 |
| LOXL2 | lysyl oxidase-like 2 | 0.00952428 |
| CALU | calumenin | 0.00950219 |
| B2M | beta-2-microglobulin | 0.00949813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00944374 |
| RPS18 | ribosomal protein S18 | 0.00942192 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00937312 |
| TNRC6B | trinucleotide repeat containing 6B | 0.00933818 |
| COL5A1 | collagen, type V, alpha 1 | 0.00927948 |
| SET | SET nuclear proto-oncogene | 0.00927318 |
| SMAD3 | SMAD family member 3 | 0.00921775 |
| NDRG1 | N-myc downstream regulated 1 | 0.00916597 |
| CLIC4 | chloride intracellular channel 4 | 0.00911176 |
| MT2A | metallothionein 2A | 0.00905428 |
| PLEC | plectin | 0.00904731 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00900062 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00894712 |
| HLA-A | major histocompatibility complex, class I, A | 0.00880024 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.00865223 |
| OGA | O-GlcNAcase | 0.00861441 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.00861232 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00853829 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.00851874 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0084883 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00842083 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00832766 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00829251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.0863227 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0507392 |
| PDE10A | phosphodiesterase 10A | -0.0454188 |
| CADM1 | cell adhesion molecule 1 | -0.0393971 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0238544 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0197483 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0197149 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0188288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0188284 |
| PLIN2 | perilipin 2 | -0.0186428 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0184986 |
| ATP13A3 | ATPase type 13A3 | -0.0183074 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0179377 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0171636 |
| ADM | adrenomedullin | -0.0169028 |
| GLIS3 | GLIS family zinc finger 3 | -0.0166672 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0162573 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0158445 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0154098 |
| HELZ | helicase with zinc finger | -0.0153747 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0152411 |
| SPAG9 | sperm associated antigen 9 | -0.0146255 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.014195 |
| LRRC7 | leucine rich repeat containing 7 | -0.0136174 |
| GOLGA4 | golgin A4 | -0.0134738 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0133253 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0130885 |
| IER3 | immediate early response 3 | -0.0129316 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0126801 |
| RBM39 | RNA binding motif protein 39 | -0.0124922 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0122415 |
| QKI | QKI, KH domain containing, RNA binding | -0.0119738 |
| PRR16 | proline rich 16 | -0.0119179 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0117354 |
| TMSB10 | thymosin beta 10 | -0.0114238 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0113433 |
| RAI14 | retinoic acid induced 14 | -0.0111869 |
| SNX9 | sorting nexin 9 | -0.0110957 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0110683 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0108257 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0107848 |
| TENM2 | teneurin transmembrane protein 2 | -0.010432 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0103306 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0102985 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.010164 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0100605 |
| OPTN | optineurin | -0.00999456 |
| AFF4 | AF4/FMR2 family, member 4 | -0.00999187 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.00993552 |
| FRMD4A | FERM domain containing 4A | -0.00984731 |
| MMP12 | matrix metallopeptidase 12 | -0.00978864 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0097804 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00977087 |
| RPS25 | ribosomal protein S25 | -0.00974005 |
| GPC6 | glypican 6 | -0.00971898 |
| ASTN2 | astrotactin 2 | -0.00966061 |
| RPS8 | ribosomal protein S8 | -0.00960384 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.00958238 |
| NGLY1 | N-glycanase 1 | -0.00957213 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.00954915 |
| MAP4 | microtubule-associated protein 4 | -0.00946885 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00940306 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.00918542 |
| RPS12 | ribosomal protein S12 | -0.00917642 |
| RPS6 | ribosomal protein S6 | -0.00904995 |
| NAV1 | neuron navigator 1 | -0.00897579 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.00887835 |
| NRN1 | neuritin 1 | -0.00885588 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00874142 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00873666 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.00872868 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.00872175 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00870434 |
| RNF145 | ring finger protein 145 | -0.00865383 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00862513 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.00860902 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.00856678 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.00850874 |
| ATXN10 | ataxin 10 | -0.00847958 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.00844467 |
| BBX | bobby sox homolog (Drosophila) | -0.00839819 |
| SRP54 | signal recognition particle 54kDa | -0.00837952 |
| ARFGEF3 | ARFGEF family member 3 | -0.00835091 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00833545 |
| CLTC | clathrin, heavy chain (Hc) | -0.00827093 |
| EXOC6B | exocyst complex component 6B | -0.00818338 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00815779 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00805002 |
| MAP1B | microtubule-associated protein 1B | -0.00802491 |
| C3 | complement component 3 | -0.00798618 |
| MTDH | metadherin | -0.00793502 |
| RPL19 | ribosomal protein L19 | -0.00790217 |
| SEPTIN7 | septin 7 | -0.00789628 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.00789525 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0078505 |
| SEC24A | SEC24 family member A | -0.00782643 |
| CFDP1 | craniofacial development protein 1 | -0.00781982 |
| TMEM132D | transmembrane protein 132D | -0.00777429 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00775164 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.00761355 |
