| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.128534 |
| NRXN3 | neurexin 3 | 0.101465 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0943847 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0840672 |
| NDRG1 | N-myc downstream regulated 1 | 0.0762142 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0680856 |
| MAP1B | microtubule-associated protein 1B | 0.0618873 |
| GLIS3 | GLIS family zinc finger 3 | 0.0511361 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0474735 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0464864 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0441219 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0440493 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0425524 |
| RNF145 | ring finger protein 145 | 0.0422311 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.041196 |
| LOX | lysyl oxidase | 0.0395524 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0389451 |
| ZNF292 | zinc finger protein 292 | 0.0378463 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.037472 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0369765 |
| EFNA5 | ephrin-A5 | 0.0359766 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0359465 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0359259 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.035166 |
| MEF2A | myocyte enhancer factor 2A | 0.0344199 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0343565 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0342737 |
| ARRDC3 | arrestin domain containing 3 | 0.0339933 |
| VEGFA | vascular endothelial growth factor A | 0.0336164 |
| RAB31 | RAB31, member RAS oncogene family | 0.0334985 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.033305 |
| COG5 | component of oligomeric golgi complex 5 | 0.0330539 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0320873 |
| CANX | calnexin | 0.0317042 |
| EGFR | epidermal growth factor receptor | 0.0315093 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0307016 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0300008 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0296476 |
| SUCO | SUN domain containing ossification factor | 0.0295314 |
| CALR | calreticulin | 0.0293736 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0293167 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0290083 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0284777 |
| HLA-C | major histocompatibility complex, class I, C | 0.0282902 |
| XPO1 | exportin 1 | 0.0281916 |
| TMEM123 | transmembrane protein 123 | 0.0276334 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0276267 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.02751 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0273012 |
| ANLN | anillin, actin binding protein | 0.0272629 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0270531 |
| YME1L1 | YME1-like 1 ATPase | 0.0269694 |
| INSIG2 | insulin induced gene 2 | 0.02657 |
| PKM | pyruvate kinase, muscle | 0.0260277 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0258327 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0257395 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0256957 |
| STC2 | stanniocalcin 2 | 0.0254216 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0253104 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0250332 |
| SQSTM1 | sequestosome 1 | 0.0249494 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0248956 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0248811 |
| MKI67 | marker of proliferation Ki-67 | 0.0247432 |
| ARF1 | ADP-ribosylation factor 1 | 0.0238933 |
| FLOT1 | flotillin 1 | 0.0238081 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0237135 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0236117 |
| SZT2 | seizure threshold 2 homolog (mouse) | 0.0235879 |
| COG6 | component of oligomeric golgi complex 6 | 0.0231793 |
| AHR | aryl hydrocarbon receptor | 0.0231694 |
| CMIP | c-Maf inducing protein | 0.0230634 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.023007 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0229107 |
| RYBP | RING1 and YY1 binding protein | 0.0228235 |
| WASF2 | WAS protein family, member 2 | 0.0227991 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0227625 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0227333 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0227072 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0226426 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0226361 |
| ATP13A3 | ATPase type 13A3 | 0.0226002 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0225818 |
| FAM120A | family with sequence similarity 120A | 0.0225765 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.022527 |
| MORF4L2 | mortality factor 4 like 2 | 0.0221042 |
| TGDS | TDP-glucose 4,6-dehydratase | 0.0220267 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0220032 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.021914 |
| VMP1 | vacuole membrane protein 1 | 0.0218844 |
| CCNL1 | cyclin L1 | 0.021807 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.021778 |
| COL5A1 | collagen, type V, alpha 1 | 0.0216945 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0216017 |
| PDGFC | platelet derived growth factor C | 0.021508 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0214946 |
| VEGFC | vascular endothelial growth factor C | 0.0214897 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0214352 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0213112 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0212996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.183627 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174161 |
| MT2A | metallothionein 2A | -0.152506 |
| UBC | ubiquitin C | -0.103233 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0951134 |
| VIM | vimentin | -0.0892661 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0810024 |
| SDC4 | syndecan 4 | -0.0791606 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0695947 |
| ENO1 | enolase 1, (alpha) | -0.0695383 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.060654 |
| TXNIP | thioredoxin interacting protein | -0.0591602 |
| SPAG9 | sperm associated antigen 9 | -0.0567107 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0541267 |
| WTAP | Wilms tumor 1 associated protein | -0.0510241 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0508472 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0500977 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0497196 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0494113 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0489658 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0467956 |
| ACTG1 | actin gamma 1 | -0.0467762 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0466581 |
| FTL | ferritin, light polypeptide | -0.0466103 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0465933 |
| PTMA | prothymosin, alpha | -0.0465222 |
| ANXA5 | annexin A5 | -0.0459187 |
| RPL23 | ribosomal protein L23 | -0.0456814 |
| FLNB | filamin B, beta | -0.0453014 |
| FN1 | fibronectin 1 | -0.0451716 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0441911 |
| CCNI | cyclin I | -0.0432496 |
| ZNF207 | zinc finger protein 207 | -0.0428501 |
| IL6 | interleukin 6 | -0.0428456 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0423891 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0423797 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.041563 |
| RPS6 | ribosomal protein S6 | -0.0411333 |
| POTEF | POTE ankyrin domain family, member F | -0.0407959 |
| RPLP1 | ribosomal protein, large, P1 | -0.0406543 |
| CDK6 | cyclin-dependent kinase 6 | -0.0405426 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0403716 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0400158 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0396523 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0388939 |
| FLNA | filamin A, alpha | -0.0377628 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0367127 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0366439 |
| SMAD3 | SMAD family member 3 | -0.036589 |
| RTN4 | reticulon 4 | -0.0359267 |
| RPS25 | ribosomal protein S25 | -0.0356993 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0353367 |
| RPS3 | ribosomal protein S3 | -0.0352835 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034687 |
| RPS11 | ribosomal protein S11 | -0.0342412 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0338758 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0336637 |
| RPS8 | ribosomal protein S8 | -0.033464 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0329663 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0328142 |
| SEC24D | SEC24 family member D | -0.0325359 |
| RPS4X | ribosomal protein S4, X-linked | -0.032484 |
| RPL37A | ribosomal protein L37a | -0.0323391 |
| CALU | calumenin | -0.0320293 |
| TOP1 | topoisomerase (DNA) I | -0.0315494 |
| THOC2 | THO complex 2 | -0.0315295 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0311899 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0311774 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0300456 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0299944 |
| RIGI | RNA sensor RIG-I | -0.0297073 |
| FAM3C | family with sequence similarity 3, member C | -0.0296824 |
| LONP2 | lon peptidase 2, peroxisomal | -0.029554 |
| ANKRD17 | ankyrin repeat domain 17 | -0.029422 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0286745 |
| RPS27A | ribosomal protein S27a | -0.0282138 |
| FMNL2 | formin-like 2 | -0.0278338 |
| CCDC88A | coiled-coil domain containing 88A | -0.0275236 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0274028 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0273168 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0269656 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0268688 |
| SRPK2 | SRSF protein kinase 2 | -0.0268337 |
| CD44 | CD44 molecule (Indian blood group) | -0.0268197 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0268122 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0266922 |
| FBXO11 | F-box protein 11 | -0.0265581 |
| AHNAK | AHNAK nucleoprotein | -0.0264738 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0261603 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0256148 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0255876 |
| DEK | DEK proto-oncogene | -0.02554 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0253956 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0252437 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0252314 |
| JUN | jun proto-oncogene | -0.0252258 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0250788 |
| QKI | QKI, KH domain containing, RNA binding | -0.0250592 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0249878 |
| TPM4 | tropomyosin 4 | -0.0249544 |
