| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0983547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0951092 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0739736 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0717521 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0684541 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0639213 |
| TXNRD1 | thioredoxin reductase 1 | 0.0638725 |
| PCBP2 | poly(rC) binding protein 2 | 0.0530746 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.049972 |
| RBM39 | RNA binding motif protein 39 | 0.0493561 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0488748 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0482565 |
| LDHA | lactate dehydrogenase A | 0.0470103 |
| YBX3 | Y box binding protein 3 | 0.0423124 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.040213 |
| CALR | calreticulin | 0.0399891 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0393099 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0377446 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0374205 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0372408 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.036507 |
| KIF5B | kinesin family member 5B | 0.0356442 |
| CANX | calnexin | 0.0350629 |
| CALU | calumenin | 0.0349187 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0345304 |
| COG6 | component of oligomeric golgi complex 6 | 0.0331289 |
| ARRDC3 | arrestin domain containing 3 | 0.0325334 |
| YBX1 | Y box binding protein 1 | 0.0325174 |
| NUP58 | nucleoporin 58 | 0.0323405 |
| MORF4L2 | mortality factor 4 like 2 | 0.0320377 |
| PKM | pyruvate kinase, muscle | 0.0313594 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0312403 |
| TMEM167A | transmembrane protein 167A | 0.030599 |
| SEC24A | SEC24 family member A | 0.0305227 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.030447 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0303424 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0298979 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0295938 |
| TBK1 | TANK-binding kinase 1 | 0.0290487 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0290302 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0288461 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0282419 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0282152 |
| HMGB2 | high mobility group box 2 | 0.0281276 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0280325 |
| CREBRF | CREB3 regulatory factor | 0.0279297 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0278067 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0277773 |
| ZNF292 | zinc finger protein 292 | 0.0277632 |
| ANXA1 | annexin A1 | 0.0274465 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0273145 |
| COG5 | component of oligomeric golgi complex 5 | 0.0271147 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0270274 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.026635 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0265544 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.02629 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0260969 |
| ANLN | anillin, actin binding protein | 0.0259252 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0254163 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0252423 |
| ATXN2 | ataxin 2 | 0.0251451 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0250989 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0248657 |
| HELZ | helicase with zinc finger | 0.0248588 |
| TPX2 | TPX2, microtubule-associated | 0.0248355 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0248287 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0245707 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0244793 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0244471 |
| SET | SET nuclear proto-oncogene | 0.0244439 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0242932 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0241533 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0240465 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0238458 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0238125 |
| DSCAM | Down syndrome cell adhesion molecule | 0.023713 |
| QKI | QKI, KH domain containing, RNA binding | 0.0237127 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0236754 |
| RAB5A | RAB5A, member RAS oncogene family | 0.023266 |
| STK24 | serine/threonine kinase 24 | 0.0232476 |
| KLHL24 | kelch-like family member 24 | 0.0232138 |
| CEP250 | centrosomal protein 250kDa | 0.0231872 |
| ARCN1 | archain 1 | 0.0231138 |
| NCKAP1 | NCK-associated protein 1 | 0.0229145 |
| ZNF652 | zinc finger protein 652 | 0.0228904 |
| RAI1 | retinoic acid induced 1 | 0.022809 |
| YTHDC1 | YTH domain containing 1 | 0.0227424 |
| COPA | coatomer protein complex, subunit alpha | 0.0226507 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0226478 |
| TFG | TRK-fused gene | 0.0225832 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0222244 |
| FAM13A | family with sequence similarity 13, member A | 0.0221815 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0221076 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0220608 |
| MYOF | myoferlin | 0.0220562 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0218865 |
| RBM33 | RNA binding motif protein 33 | 0.0217629 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0216663 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0215942 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0215862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244055 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.165047 |
| VIM | vimentin | -0.117643 |
| TMSB10 | thymosin beta 10 | -0.0953025 |
| CD44 | CD44 molecule (Indian blood group) | -0.0797905 |
| HMGA2 | high mobility group AT-hook 2 | -0.0791588 |
| PRSS23 | protease, serine, 23 | -0.065379 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0625596 |
| SMYD3 | SET and MYND domain containing 3 | -0.0620335 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.062009 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0573773 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0560672 |
| IGF2 | insulin-like growth factor 2 | -0.0542226 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0534683 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0520214 |
| ANGPTL4 | angiopoietin-like 4 | -0.0501895 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0489485 |
| LMO7 | LIM domain 7 | -0.0471488 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0468426 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.046365 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.04447 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0443816 |
| PRKCA | protein kinase C, alpha | -0.0443476 |
| RIGI | RNA sensor RIG-I | -0.0440319 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0439094 |
| RPL35A | ribosomal protein L35a | -0.0433608 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0430425 |
| NAV2 | neuron navigator 2 | -0.0423167 |
| ACTG1 | actin gamma 1 | -0.040219 |
| PTK2 | protein tyrosine kinase 2 | -0.040094 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0394159 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0391391 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0389506 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0369583 |
| RPS8 | ribosomal protein S8 | -0.0368644 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0361621 |
| FLNB | filamin B, beta | -0.0361148 |
| PODXL | podocalyxin-like | -0.0354563 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0351363 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0349856 |
| RPL26 | ribosomal protein L26 | -0.0347101 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0345247 |
| CCDC91 | coiled-coil domain containing 91 | -0.0345239 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0341331 |
| POTEF | POTE ankyrin domain family, member F | -0.033976 |
| DST | dystonin | -0.0339422 |
| RPS13 | ribosomal protein S13 | -0.0339112 |
| ATG7 | autophagy related 7 | -0.0335459 |
| VCL | vinculin | -0.0331785 |
| ATXN1 | ataxin 1 | -0.0328227 |
| FMN1 | formin 1 | -0.0321502 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0320458 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0316606 |
| OSMR | oncostatin M receptor | -0.0316259 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0308081 |
| RAI14 | retinoic acid induced 14 | -0.0300677 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0300375 |
| S100A10 | S100 calcium binding protein A10 | -0.0298458 |
| NAV3 | neuron navigator 3 | -0.0296911 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0291584 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0291286 |
| SATB2 | SATB homeobox 2 | -0.0287015 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0286637 |
| TRIM56 | tripartite motif containing 56 | -0.0285695 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0285114 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0278241 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0278015 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0276434 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0275971 |
| CDK6 | cyclin-dependent kinase 6 | -0.0274346 |
| RPS3 | ribosomal protein S3 | -0.0272648 |
| TCF12 | transcription factor 12 | -0.0271215 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.026853 |
| NALCN | sodium leak channel, non selective | -0.0268185 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0267114 |
| RPS24 | ribosomal protein S24 | -0.026695 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0266414 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0264607 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0261553 |
| RAD51B | RAD51 paralog B | -0.0260513 |
| WWOX | WW domain containing oxidoreductase | -0.0257715 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.025684 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0254117 |
| EXOC4 | exocyst complex component 4 | -0.0248565 |
| CCND1 | cyclin D1 | -0.0248248 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0245372 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0244653 |
| RPLP1 | ribosomal protein, large, P1 | -0.0244509 |
| PRR16 | proline rich 16 | -0.0242734 |
| DEK | DEK proto-oncogene | -0.023891 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0238368 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0237549 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0237381 |
| CAVIN1 | caveolae associated protein 1 | -0.0236669 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0235009 |
| PCED1B | PC-esterase domain containing 1B | -0.023464 |
| COL5A1 | collagen, type V, alpha 1 | -0.0234187 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0233777 |
| RBM25 | RNA binding motif protein 25 | -0.02314 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0230715 |
