| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.14045 |
| FTL | ferritin, light polypeptide | 0.0811513 |
| SFTPA2 | surfactant protein A2 | 0.047137 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.04571 |
| INTS6 | integrator complex subunit 6 | 0.042121 |
| MCL1 | myeloid cell leukemia 1 | 0.036104 |
| VEGFA | vascular endothelial growth factor A | 0.034769 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0330848 |
| STC2 | stanniocalcin 2 | 0.0328554 |
| RPL35A | ribosomal protein L35a | 0.0320746 |
| SQSTM1 | sequestosome 1 | 0.028653 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0283196 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0265147 |
| EGR1 | early growth response 1 | 0.0264826 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0263098 |
| RPL31 | ribosomal protein L31 | 0.0241659 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0236847 |
| TGFB1 | transforming growth factor, beta 1 | 0.0224681 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0223653 |
| B2M | beta-2-microglobulin | 0.021852 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0218113 |
| PLEC | plectin | 0.0216276 |
| RPS27 | ribosomal protein S27 | 0.0211378 |
| HLA-B | major histocompatibility complex, class I, B | 0.0210633 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0210303 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0210019 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0200753 |
| MX1 | MX dynamin-like GTPase 1 | 0.0196291 |
| LRRC23 | leucine rich repeat containing 23 | 0.0195013 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.019461 |
| HLA-A | major histocompatibility complex, class I, A | 0.0187668 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0185034 |
| CANX | calnexin | 0.0184825 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.01822 |
| IFI44L | interferon-induced protein 44-like | 0.018168 |
| PTMA | prothymosin, alpha | 0.0180205 |
| NRG1 | neuregulin 1 | 0.0179889 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0177311 |
| CST3 | cystatin C | 0.0172823 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0171856 |
| SMOX | spermine oxidase | 0.0168712 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0167902 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0166291 |
| RPL11 | ribosomal protein L11 | 0.0165987 |
| PCDH7 | protocadherin 7 | 0.0164287 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.016122 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0161071 |
| PDE10A | phosphodiesterase 10A | 0.0155686 |
| PKM | pyruvate kinase, muscle | 0.0154245 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 0.0152756 |
| APP | amyloid beta (A4) precursor protein | 0.0151793 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0150979 |
| ATF4 | activating transcription factor 4 | 0.0150165 |
| LDHA | lactate dehydrogenase A | 0.014778 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0146264 |
| CALR | calreticulin | 0.0144183 |
| CCNL1 | cyclin L1 | 0.0142993 |
| CDH13 | cadherin 13 | 0.0141704 |
| RPS13 | ribosomal protein S13 | 0.0138976 |
| YLPM1 | YLP motif containing 1 | 0.0135708 |
| DSPP | dentin sialophosphoprotein | 0.0135374 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0134476 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0134314 |
| COG5 | component of oligomeric golgi complex 5 | 0.0132037 |
| RPS14 | ribosomal protein S14 | 0.0131619 |
| HDAC8 | histone deacetylase 8 | 0.013156 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0131536 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0130874 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0130768 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0130737 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0130655 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0129766 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.012902 |
| ZYX | zyxin | 0.0128825 |
| GLCCI1 | glucocorticoid induced 1 | 0.0128798 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | 0.0127672 |
| AREG | amphiregulin | 0.0126687 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0126636 |
| IER5 | immediate early response 5 | 0.0126287 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0125433 |
| VGF | VGF nerve growth factor inducible | 0.0125029 |
| RPS8 | ribosomal protein S8 | 0.0123937 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0123395 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0123127 |
| HMGB3 | high mobility group box 3 | 0.0122789 |
| OSTC | oligosaccharyltransferase complex subunit (non-catalytic) | 0.0122399 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0122072 |
| FBN1 | fibrillin 1 | 0.012076 |
| FMNL2 | formin-like 2 | 0.0120706 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0119826 |
| COL5A2 | collagen, type V, alpha 2 | 0.0119568 |
| ERP44 | endoplasmic reticulum protein 44 | 0.0118833 |
| PELO | pelota homolog (Drosophila) | 0.0118558 |
| RPL37 | ribosomal protein L37 | 0.0117583 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0117568 |
| GUK1 | guanylate kinase 1 | 0.0116603 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0116444 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.0116011 |
| ATP11A | ATPase, class VI, type 11A | 0.0115581 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0115524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.263404 |
| FN1 | fibronectin 1 | -0.150838 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.117285 |
| HMGA2 | high mobility group AT-hook 2 | -0.0988761 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.09131 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0840803 |
| ASPH | aspartate beta-hydroxylase | -0.0735316 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.069711 |
| UBC | ubiquitin C | -0.068803 |
| AHR | aryl hydrocarbon receptor | -0.0680104 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0673279 |
| PTK2 | protein tyrosine kinase 2 | -0.0547749 |
| S100A6 | S100 calcium binding protein A6 | -0.0529333 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0523745 |
| CENPF | centromere protein F, 350/400kDa | -0.05082 |
| TXNIP | thioredoxin interacting protein | -0.0503603 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.050082 |
| DST | dystonin | -0.0500723 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0496912 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0488846 |
| MT2A | metallothionein 2A | -0.0480636 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0480151 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0477875 |
| SPAG9 | sperm associated antigen 9 | -0.0474579 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0469635 |
| MAP1B | microtubule-associated protein 1B | -0.0460506 |
| CDC73 | cell division cycle 73 | -0.0455831 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0446628 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.043694 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0433939 |
| VIM | vimentin | -0.0430986 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.042971 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0429087 |
| RUNX2 | runt-related transcription factor 2 | -0.0428242 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0424392 |
| CALU | calumenin | -0.0417482 |
| ITGA1 | integrin, alpha 1 | -0.0409258 |
| MKI67 | marker of proliferation Ki-67 | -0.0407632 |
| GLIS3 | GLIS family zinc finger 3 | -0.039925 |
| AHNAK | AHNAK nucleoprotein | -0.039653 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0391687 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0383612 |
| TPR | translocated promoter region, nuclear basket protein | -0.0379889 |
| NRP1 | neuropilin 1 | -0.0379062 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0376546 |
| ZNF292 | zinc finger protein 292 | -0.0370254 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0366737 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0366627 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0363488 |
| TMSB4X | thymosin beta 4, X-linked | -0.0352519 |
| VCL | vinculin | -0.0349481 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0348932 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0348181 |
| OSMR | oncostatin M receptor | -0.0346503 |
| RPL26 | ribosomal protein L26 | -0.0342118 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0341539 |
| SUCO | SUN domain containing ossification factor | -0.0338528 |
| TMEM131 | transmembrane protein 131 | -0.0332052 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0332038 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0331058 |
| CLTC | clathrin, heavy chain (Hc) | -0.0330424 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0326786 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0323564 |
| RPS27A | ribosomal protein S27a | -0.0321659 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0321178 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0321159 |
| SEPTIN7 | septin 7 | -0.0319104 |
| RNF145 | ring finger protein 145 | -0.0316079 |
| H1-0 | H1.0 linker histone | -0.0315273 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0309478 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0308856 |
| RASAL2 | RAS protein activator like 2 | -0.0304056 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0303609 |
| DENND5B | DENN/MADD domain containing 5B | -0.0302244 |
| TFG | TRK-fused gene | -0.030061 |
| FOXP1 | forkhead box P1 | -0.0300443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0299791 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299327 |
| FNBP1 | formin binding protein 1 | -0.0293446 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0292921 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0288622 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0287171 |
| SMYD3 | SET and MYND domain containing 3 | -0.0286638 |
| COPA | coatomer protein complex, subunit alpha | -0.0285275 |
| FAF2 | Fas associated factor family member 2 | -0.0285121 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.028301 |
| FAM13A | family with sequence similarity 13, member A | -0.0282909 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0276384 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0275902 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0275304 |
| SYNJ2 | synaptojanin 2 | -0.0274833 |
| FBXO34 | F-box protein 34 | -0.0274259 |
| RO60 | Ro60, Y RNA binding protein | -0.0274068 |
| ETV6 | ets variant 6 | -0.0273921 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0272768 |
| OGA | O-GlcNAcase | -0.0272725 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0272486 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0272109 |
| LOXL2 | lysyl oxidase-like 2 | -0.0272018 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0270495 |
