| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.142359 |
| PTMA | prothymosin, alpha | 0.131081 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0733553 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0639178 |
| EZR | ezrin | 0.0567655 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.053156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0518698 |
| LDHA | lactate dehydrogenase A | 0.0510466 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0476957 |
| B2M | beta-2-microglobulin | 0.0460553 |
| TMSB10 | thymosin beta 10 | 0.0460129 |
| VCL | vinculin | 0.0451025 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0427559 |
| RPS6 | ribosomal protein S6 | 0.0398201 |
| KRT18 | keratin 18, type I | 0.0387007 |
| EGR1 | early growth response 1 | 0.0382883 |
| RPS3 | ribosomal protein S3 | 0.0375816 |
| RPL35A | ribosomal protein L35a | 0.0369156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0353953 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0352838 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0349614 |
| CANX | calnexin | 0.0349398 |
| PKM | pyruvate kinase, muscle | 0.0347627 |
| MYO1E | myosin IE | 0.033719 |
| BCL2L1 | BCL2-like 1 | 0.0336736 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0335976 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0335443 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0324699 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0313137 |
| EHBP1 | EH domain binding protein 1 | 0.0312708 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0304751 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0302771 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.030267 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0297405 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0295905 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0292739 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0291013 |
| TPM4 | tropomyosin 4 | 0.0290152 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0284514 |
| NDRG1 | N-myc downstream regulated 1 | 0.0284215 |
| RPL12 | ribosomal protein L12 | 0.0283559 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0278784 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0277585 |
| RPL31 | ribosomal protein L31 | 0.0276669 |
| GNAS | GNAS complex locus | 0.0274309 |
| INTS6 | integrator complex subunit 6 | 0.0272603 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0271664 |
| PGK1 | phosphoglycerate kinase 1 | 0.0270815 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0265705 |
| RPS12 | ribosomal protein S12 | 0.0264093 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0256929 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0256575 |
| RPL37A | ribosomal protein L37a | 0.0256374 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.025465 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0254115 |
| RNF213 | ring finger protein 213 | 0.025283 |
| DSPP | dentin sialophosphoprotein | 0.0252746 |
| FAT1 | FAT atypical cadherin 1 | 0.0252507 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0252382 |
| CUX1 | cut-like homeobox 1 | 0.0250075 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0248198 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0246585 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0246424 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0245974 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0244175 |
| HLA-A | major histocompatibility complex, class I, A | 0.024416 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0241632 |
| RPS25 | ribosomal protein S25 | 0.0240265 |
| CALR | calreticulin | 0.0239742 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0239685 |
| RPS13 | ribosomal protein S13 | 0.0238356 |
| RPS19 | ribosomal protein S19 | 0.0236037 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.023512 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0233364 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0232231 |
| RPL23 | ribosomal protein L23 | 0.022891 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0228438 |
| ANXA2 | annexin A2 | 0.0227437 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0223776 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0223046 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0222705 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0222535 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0222375 |
| RPLP1 | ribosomal protein, large, P1 | 0.0221711 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0221366 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0219396 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0216345 |
| EXOC4 | exocyst complex component 4 | 0.0214749 |
| RACK1 | receptor for activated C kinase 1 | 0.0212932 |
| NEBL | nebulette | 0.0211245 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0210909 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0210005 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0209785 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.02097 |
| EPCAM | epithelial cell adhesion molecule | 0.0208925 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0208203 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.020795 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0207273 |
| RPL18 | ribosomal protein L18 | 0.0206822 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0203821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0233278 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0217902 |
| USP3 | ubiquitin specific peptidase 3 | -0.0214991 |
| H1-0 | H1.0 linker histone | -0.0211358 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0200887 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0182809 |
| CCNL1 | cyclin L1 | -0.0174752 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0174556 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0165256 |
| ZNF292 | zinc finger protein 292 | -0.0157883 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0157316 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0149399 |
| MATR3 | matrin 3 | -0.014785 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0140552 |
| MTMR3 | myotubularin related protein 3 | -0.0138762 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0138731 |
| FAM3C | family with sequence similarity 3, member C | -0.0138555 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0136994 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0131854 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0124188 |
| TMEM39A | transmembrane protein 39A | -0.0121046 |
| RTN4 | reticulon 4 | -0.0118936 |
| TXNRD1 | thioredoxin reductase 1 | -0.0115119 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0113482 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0113482 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0112405 |
| MEF2A | myocyte enhancer factor 2A | -0.011039 |
| NCKAP1 | NCK-associated protein 1 | -0.0109981 |
| OLA1 | Obg-like ATPase 1 | -0.0104119 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0101868 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00973026 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.00955095 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00949442 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00940386 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.00933627 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | -0.00931273 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00919401 |
| PHKB | phosphorylase kinase, beta | -0.00914092 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00901716 |
| NEK7 | NIMA-related kinase 7 | -0.00895893 |
| PREPL | prolyl endopeptidase-like | -0.00882837 |
| AFDN | afadin, adherens junction formation factor | -0.00867533 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.00847871 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00844083 |
| TCERG1 | transcription elongation regulator 1 | -0.00844003 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.00842816 |
| DIDO1 | death inducer-obliterator 1 | -0.00838123 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.00831633 |
| HOXA3 | homeobox A3 | -0.00817319 |
| TFG | TRK-fused gene | -0.00812862 |
| XPO1 | exportin 1 | -0.0081147 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.00809704 |
| RREB1 | ras responsive element binding protein 1 | -0.00805529 |
| RYK | receptor-like tyrosine kinase | -0.00798259 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00796319 |
| SNRK | SNF related kinase | -0.00790618 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.00788128 |
| UBQLN1 | ubiquilin 1 | -0.0078422 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00781286 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.00780759 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0076972 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00769709 |
| HBS1L | HBS1-like translational GTPase | -0.0075893 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00757943 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00755409 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0075105 |
| BTBD10 | BTB (POZ) domain containing 10 | -0.0075055 |
| SARNP | SAP domain containing ribonucleoprotein | -0.00749 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00745995 |
| RBM39 | RNA binding motif protein 39 | -0.00744438 |
| CCNT2 | cyclin T2 | -0.00736047 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.00732557 |
| FMR1 | fragile X mental retardation 1 | -0.00730292 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.00724878 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0072412 |
| PDS5B | PDS5 cohesin associated factor B | -0.00720288 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 | -0.00717256 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.00714481 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.007144 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.00703989 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00698786 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.00696624 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0069318 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.00693012 |
| TNPO1 | transportin 1 | -0.00692192 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | -0.0069049 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.00679848 |
| NPTN | neuroplastin | -0.00679733 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.00672297 |
| RYBP | RING1 and YY1 binding protein | -0.00666712 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.00663766 |
| SUCO | SUN domain containing ossification factor | -0.00655446 |
| ECT2 | epithelial cell transforming 2 | -0.00648373 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.00646425 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00641773 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00638064 |
| SNX4 | sorting nexin 4 | -0.00635887 |
| FAM133B | family with sequence similarity 133, member B | -0.00634779 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00632224 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | -0.00625256 |
