| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.120925 |
| LMO7 | LIM domain 7 | 0.0969974 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0934186 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0796237 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0765848 |
| EGFR | epidermal growth factor receptor | 0.0695834 |
| FAT1 | FAT atypical cadherin 1 | 0.0597591 |
| LAMC2 | laminin, gamma 2 | 0.0586155 |
| TXNRD1 | thioredoxin reductase 1 | 0.0555579 |
| RNF43 | ring finger protein 43 | 0.0548016 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0503937 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0464615 |
| FHL2 | four and a half LIM domains 2 | 0.0463426 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0461807 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0448543 |
| YAP1 | Yes-associated protein 1 | 0.0427182 |
| AHNAK | AHNAK nucleoprotein | 0.0406712 |
| TOP1 | topoisomerase (DNA) I | 0.0380354 |
| RPL32 | ribosomal protein L32 | 0.0370628 |
| RPLP0 | ribosomal protein, large, P0 | 0.0369339 |
| LDHA | lactate dehydrogenase A | 0.0362636 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0351464 |
| VCL | vinculin | 0.0348233 |
| PKM | pyruvate kinase, muscle | 0.0341768 |
| RPLP1 | ribosomal protein, large, P1 | 0.0340475 |
| RPS18 | ribosomal protein S18 | 0.0337496 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0335227 |
| RPL26 | ribosomal protein L26 | 0.0333418 |
| DUSP4 | dual specificity phosphatase 4 | 0.0333008 |
| CLDND1 | claudin domain containing 1 | 0.0323787 |
| DSPP | dentin sialophosphoprotein | 0.0322901 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0321717 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0321261 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0318538 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0315697 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0314843 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0300755 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0298683 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0293293 |
| LAMB3 | laminin, beta 3 | 0.0288563 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0284216 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0277343 |
| ANXA11 | annexin A11 | 0.0275793 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0272146 |
| ATXN1 | ataxin 1 | 0.0267076 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0265503 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0263097 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0262792 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257691 |
| SMAD3 | SMAD family member 3 | 0.0256935 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0256571 |
| ECT2 | epithelial cell transforming 2 | 0.0253469 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0253282 |
| RPS4X | ribosomal protein S4, X-linked | 0.0251852 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0249492 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0243106 |
| YBX1 | Y box binding protein 1 | 0.0241564 |
| KRT8 | keratin 8, type II | 0.0240862 |
| SFTPA2 | surfactant protein A2 | 0.0239283 |
| USP6NL | USP6 N-terminal like | 0.0234988 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0232399 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0231356 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0231277 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0229178 |
| UBC | ubiquitin C | 0.0224654 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.022398 |
| RPL7 | ribosomal protein L7 | 0.0223901 |
| RUNX2 | runt-related transcription factor 2 | 0.0223705 |
| ANXA2 | annexin A2 | 0.0220913 |
| CANX | calnexin | 0.0215833 |
| TPM3 | tropomyosin 3 | 0.021367 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.02136 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0213538 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0213054 |
| RPL3 | ribosomal protein L3 | 0.0212913 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0211339 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.021114 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0210667 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0209274 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0208911 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0207492 |
| HSPA8 | heat shock 70kDa protein 8 | 0.020718 |
| MED13 | mediator complex subunit 13 | 0.0203651 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0202651 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0202112 |
| UBN2 | ubinuclein 2 | 0.0200797 |
| RPS17 | ribosomal protein S17 | 0.0200164 |
| RPL11 | ribosomal protein L11 | 0.0199697 |
| RPL13A | ribosomal protein L13a | 0.0199274 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0199066 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0198745 |
| CDCP1 | CUB domain containing protein 1 | 0.0197841 |
| TJP1 | tight junction protein 1 | 0.0196084 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0194987 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0189415 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0189354 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0188251 |
| AXIN2 | axin 2 | 0.018805 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0187743 |
| RPS14 | ribosomal protein S14 | 0.0186865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.10743 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.100037 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0855253 |
| ACTG1 | actin gamma 1 | -0.0710775 |
| IER3 | immediate early response 3 | -0.0619119 |
| FHIT | fragile histidine triad | -0.0560726 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0557639 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.053869 |
| CUX1 | cut-like homeobox 1 | -0.0454205 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0427503 |
| NDRG1 | N-myc downstream regulated 1 | -0.0396692 |
| FOSL1 | FOS-like antigen 1 | -0.039641 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0392462 |
| HDAC2 | histone deacetylase 2 | -0.0357045 |
| HMGA2 | high mobility group AT-hook 2 | -0.0341847 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0338971 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0338865 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0334312 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0329453 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0327602 |
| RREB1 | ras responsive element binding protein 1 | -0.0326896 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0326584 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0323901 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0303821 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0302004 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0300128 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0297634 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.029452 |
| ITGB4 | integrin, beta 4 | -0.0286519 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0283886 |
| RPL34 | ribosomal protein L34 | -0.0282371 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0272356 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.026297 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0256466 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0239401 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0237548 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0234303 |
| DIAPH2 | diaphanous-related formin 2 | -0.0234302 |
| TPR | translocated promoter region, nuclear basket protein | -0.0232712 |
| S100A10 | S100 calcium binding protein A10 | -0.0229132 |
| RPL35A | ribosomal protein L35a | -0.0228569 |
| GPC5 | glypican 5 | -0.0228402 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0218969 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0215015 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0213531 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0212891 |
| SEPTIN2 | septin 2 | -0.0212078 |
| FMNL2 | formin-like 2 | -0.0211596 |
| SCFD1 | sec1 family domain containing 1 | -0.0206134 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0203649 |
| EZR | ezrin | -0.0201506 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0199487 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0197901 |
| RRM2 | ribonucleotide reductase M2 | -0.0197837 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0197046 |
| SERINC5 | serine incorporator 5 | -0.0196536 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0196391 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0195397 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0192592 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0190709 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0190201 |
| RPL37 | ribosomal protein L37 | -0.018948 |
| RAD51B | RAD51 paralog B | -0.0187355 |
| IGF2 | insulin-like growth factor 2 | -0.0186111 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0185126 |
| MED13L | mediator complex subunit 13-like | -0.0180132 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0178762 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0176326 |
| TCERG1 | transcription elongation regulator 1 | -0.0176325 |
| CD109 | CD109 molecule | -0.0174028 |
| FRYL | FRY-like | -0.0172424 |
| MYO1B | myosin IB | -0.0171585 |
| CENPF | centromere protein F, 350/400kDa | -0.0171046 |
| PTK2 | protein tyrosine kinase 2 | -0.0170999 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0170465 |
| EXOC4 | exocyst complex component 4 | -0.0168252 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.016805 |
| DEK | DEK proto-oncogene | -0.0165714 |
| CAPN7 | calpain 7 | -0.0165622 |
| RPL37A | ribosomal protein L37a | -0.0165199 |
| ZNF292 | zinc finger protein 292 | -0.0164928 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0163393 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0162256 |
| RPL38 | ribosomal protein L38 | -0.016191 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0161624 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0161057 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0160496 |
| CBX3 | chromobox homolog 3 | -0.0160188 |
| GLO1 | glyoxalase I | -0.0160113 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0159748 |
| EMP1 | epithelial membrane protein 1 | -0.0159731 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0159626 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0156591 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0156235 |
| WWOX | WW domain containing oxidoreductase | -0.0155324 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.0155294 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0154755 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0153951 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0153884 |
| USP24 | ubiquitin specific peptidase 24 | -0.0153394 |
