| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.0918151 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0883001 |
| B2M | beta-2-microglobulin | 0.0846259 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0831175 |
| INHBA | inhibin, beta A | 0.0812841 |
| FTL | ferritin, light polypeptide | 0.0702916 |
| FN1 | fibronectin 1 | 0.06197 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0509899 |
| CALR | calreticulin | 0.049897 |
| CANX | calnexin | 0.048112 |
| COL1A1 | collagen, type I, alpha 1 | 0.0454059 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0444498 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0428475 |
| STC2 | stanniocalcin 2 | 0.0387217 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0372834 |
| HLA-A | major histocompatibility complex, class I, A | 0.0349695 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0328011 |
| CCND1 | cyclin D1 | 0.0311812 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0294202 |
| LMNA | lamin A/C | 0.027257 |
| ADM | adrenomedullin | 0.0272351 |
| FBN1 | fibrillin 1 | 0.0271932 |
| EGR1 | early growth response 1 | 0.0270521 |
| SFTPA2 | surfactant protein A2 | 0.0270345 |
| RPL35A | ribosomal protein L35a | 0.0264149 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0260506 |
| RPLP1 | ribosomal protein, large, P1 | 0.0257179 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0256837 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0247889 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0245699 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0243218 |
| SEPTIN9 | septin 9 | 0.0237033 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0225348 |
| CD63 | CD63 molecule | 0.0218218 |
| RPS19 | ribosomal protein S19 | 0.0217311 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0212893 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0211041 |
| STC1 | stanniocalcin 1 | 0.0207386 |
| VEGFA | vascular endothelial growth factor A | 0.0203888 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0203062 |
| COL3A1 | collagen, type III, alpha 1 | 0.0200999 |
| IGF2 | insulin-like growth factor 2 | 0.0197976 |
| HLA-C | major histocompatibility complex, class I, C | 0.0195825 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0195671 |
| NCKAP5 | NCK-associated protein 5 | 0.0194175 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0193697 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0193049 |
| FAM107B | family with sequence similarity 107, member B | 0.0188056 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0187827 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0186916 |
| NPTX1 | neuronal pentraxin I | 0.0185386 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0184784 |
| COL5A2 | collagen, type V, alpha 2 | 0.0184402 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0181357 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0178503 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0176158 |
| IER3 | immediate early response 3 | 0.0175494 |
| LDHA | lactate dehydrogenase A | 0.0175381 |
| DNER | delta/notch-like EGF repeat containing | 0.0174249 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0172518 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0171643 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0170794 |
| RNF213 | ring finger protein 213 | 0.0170588 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0170211 |
| GPC6 | glypican 6 | 0.0169842 |
| PTMA | prothymosin, alpha | 0.0169019 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0166753 |
| CDH13 | cadherin 13 | 0.0165603 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0164231 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0163961 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0163691 |
| MCL1 | myeloid cell leukemia 1 | 0.0162994 |
| AXL | AXL receptor tyrosine kinase | 0.0159916 |
| CAVIN1 | caveolae associated protein 1 | 0.0159444 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0158783 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0157512 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0156472 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.015407 |
| DSPP | dentin sialophosphoprotein | 0.0153696 |
| EZR | ezrin | 0.0153273 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0151652 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0150627 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0149982 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.0149726 |
| YBX3 | Y box binding protein 3 | 0.0148886 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0148149 |
| RPL31 | ribosomal protein L31 | 0.0145559 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0144762 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0143305 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0140555 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0139994 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0138969 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0137138 |
| INSIG1 | insulin induced gene 1 | 0.0137021 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0136841 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0136308 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0135895 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0135364 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.013387 |
| HLA-E | major histocompatibility complex, class I, E | 0.0133525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222749 |
| VIM | vimentin | -0.220882 |
| COL6A3 | collagen, type VI, alpha 3 | -0.160808 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.108878 |
| CD44 | CD44 molecule (Indian blood group) | -0.0909507 |
| MYO10 | myosin X | -0.0805617 |
| HMGA2 | high mobility group AT-hook 2 | -0.0787224 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0783856 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0738018 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0717743 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0672882 |
| UBC | ubiquitin C | -0.0621892 |
| FAM13A | family with sequence similarity 13, member A | -0.0619821 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0580569 |
| SPAG9 | sperm associated antigen 9 | -0.0578957 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0545955 |
| RAI14 | retinoic acid induced 14 | -0.0496446 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0494603 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -0.0465236 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0447894 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0432041 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0423842 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0421224 |
| GLIS3 | GLIS family zinc finger 3 | -0.0407241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0399806 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.039886 |
| NAV2 | neuron navigator 2 | -0.0383404 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0375603 |
| MED13L | mediator complex subunit 13-like | -0.0372013 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0368961 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0367133 |
| AHNAK | AHNAK nucleoprotein | -0.0358234 |
| LOX | lysyl oxidase | -0.0358233 |
| NDRG1 | N-myc downstream regulated 1 | -0.0353571 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0345328 |
| COPA | coatomer protein complex, subunit alpha | -0.0343976 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0336761 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0334209 |
| MAP1B | microtubule-associated protein 1B | -0.0331944 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0328651 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0327679 |
| ASPH | aspartate beta-hydroxylase | -0.0327131 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0325504 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.031938 |
| EMP1 | epithelial membrane protein 1 | -0.0316001 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0314336 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0309492 |
| OXR1 | oxidation resistance 1 | -0.0309083 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0304925 |
| CALU | calumenin | -0.0300033 |
| MMP1 | matrix metallopeptidase 1 | -0.0299302 |
| VCL | vinculin | -0.0296433 |
| ACTG1 | actin gamma 1 | -0.0294127 |
| NAV1 | neuron navigator 1 | -0.0293429 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0291319 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0289984 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.028899 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0285947 |
| ATP13A3 | ATPase type 13A3 | -0.0285012 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0282387 |
| SEPTIN11 | septin 11 | -0.0279746 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0279326 |
| ANO6 | anoctamin 6 | -0.0274697 |
| GPATCH2L | G patch domain containing 2-like | -0.0269781 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0268801 |
| NKTR | natural killer cell triggering receptor | -0.0265906 |
| KIAA1549L | KIAA1549-like | -0.0264001 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0262976 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0262861 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0262454 |
| PCBP2 | poly(rC) binding protein 2 | -0.0262285 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0260942 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0260372 |
| SETD5 | SET domain containing 5 | -0.025597 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0255622 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0253517 |
| ENO1 | enolase 1, (alpha) | -0.025124 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0250348 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0247744 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0246988 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0246349 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0245267 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0244507 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0241215 |
| GOLGA4 | golgin A4 | -0.023838 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0236154 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0234652 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0232295 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0230732 |
| PHIP | pleckstrin homology domain interacting protein | -0.0230611 |
| CDC27 | cell division cycle 27 | -0.0227513 |
| GPHN | gephyrin | -0.0224506 |
| MMP12 | matrix metallopeptidase 12 | -0.0222019 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0221982 |
| SEC24D | SEC24 family member D | -0.022057 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0218863 |
| SLC38A2 | solute carrier family 38, member 2 | -0.021881 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0218492 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0218089 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0215539 |
