| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A peptide that has formula C16H24N2O4. (Chemical Entities of Biological Interest Ontology, CHEBI_3070) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/72172 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Bestatin relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ENO1 | enolase 1, (alpha) | 2.06 |
| SBSN | suprabasin | 1.61 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 1.38 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 1.07 |
| SGCE | sarcoglycan, epsilon | 0.84 |
| TMEM64 | transmembrane protein 64 | 0.71 |
| PKHD1 | polycystic kidney and hepatic disease 1 (autosomal recessive) | 0.6 |
| PIP | prolactin-induced protein | 0.6 |
| TMSB10 | thymosin beta 10 | 0.59 |
| DAB2IP | DAB2 interacting protein | 0.53 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 0.52 |
| OFD1 | oral-facial-digital syndrome 1 | 0.51 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.5 |
| HYPK | huntingtin interacting protein K | 0.49 |
| DAP | death-associated protein | 0.47 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.46 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.45 |
| MLPH | melanophilin | 0.44 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.44 |
| MXRA7 | matrix-remodelling associated 7 | 0.44 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.43 |
| ZXDB | zinc finger, X-linked, duplicated B | 0.43 |
| ERH | enhancer of rudimentary homolog (Drosophila) | 0.43 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | 0.42 |
| OBSL1 | obscurin-like 1 | 0.42 |
| C19ORF25 | chromosome 19 open reading frame 25 | 0.42 |
| OTUD5 | OTU deubiquitinase 5 | 0.42 |
| BORCS5 | BLOC-1 related complex subunit 5 | 0.42 |
| UROS | uroporphyrinogen III synthase | 0.41 |
| ADIRF | adipogenesis regulatory factor | 0.41 |
| COX5A | cytochrome c oxidase subunit Va | 0.4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.4 |
| GLRX | glutaredoxin (thioltransferase) | 0.4 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.4 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | 0.4 |
| METTL4 | methyltransferase like 4 | 0.39 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.39 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.38 |
| RMDN2 | regulator of microtubule dynamics 2 | 0.38 |
| SUCO | SUN domain containing ossification factor | 0.38 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 0.37 |
| SRXN1 | sulfiredoxin 1 | 0.36 |
| PFDN5 | prefoldin subunit 5 | 0.36 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.36 |
| ERVK3-1 | endogenous retrovirus group K3, member 1 | 0.35 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.35 |
| RNF181 | ring finger protein 181 | 0.35 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | 0.35 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.35 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.35 |
| SLC26A11 | solute carrier family 26 (anion exchanger), member 11 | 0.34 |
| BANF1 | barrier to autointegration factor 1 | 0.33 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.33 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.33 |
| HSBP1 | heat shock factor binding protein 1 | 0.33 |
| HBA1 | hemoglobin, alpha 1 | 0.32 |
| FAM136A | family with sequence similarity 136, member A | 0.32 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 0.32 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.32 |
| ARMCX5 | armadillo repeat containing, X-linked 5 | 0.32 |
| ZBED6 | zinc finger, BED-type containing 6 | 0.32 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.31 |
| TMOD2 | tropomodulin 2 (neuronal) | 0.31 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.31 |
| TSKU | tsukushi, small leucine rich proteoglycan | 0.31 |
| MSH5 | mutS homolog 5 | 0.31 |
| PFDN1 | prefoldin subunit 1 | 0.31 |
| CDC26 | cell division cycle 26 | 0.31 |
| KLHDC3 | kelch domain containing 3 | 0.3 |
| UBL7 | ubiquitin-like 7 | 0.3 |
| TPM3 | tropomyosin 3 | 0.3 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.29 |
| MTPN | myotrophin | 0.29 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.29 |
| NUCB1 | nucleobindin 1 | 0.29 |
| TSC22D4 | TSC22 domain family, member 4 | 0.29 |
| DUS2 | dihydrouridine synthase 2 | 0.29 |
| FAM135A | family with sequence similarity 135, member A | 0.29 |
| ZFAND2A | zinc finger, AN1-type domain 2A | 0.29 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.29 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.29 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.29 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.29 |
| TPM2 | tropomyosin 2 (beta) | 0.29 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.28 |
| TNS2 | tensin 2 | 0.28 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | 0.28 |
| NUCB2 | nucleobindin 2 | 0.28 |
| ZNF175 | zinc finger protein 175 | 0.28 |
| ACOT8 | acyl-CoA thioesterase 8 | 0.28 |
| MYCBP | MYC binding protein | 0.27 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.27 |
| BID | BH3 interacting domain death agonist | 0.27 |
| CCDC57 | coiled-coil domain containing 57 | 0.27 |
| TNNC2 | troponin C type 2 (fast) | 0.27 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.27 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.27 |
| RWDD2B | RWD domain containing 2B | 0.27 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.27 |
| S100A14 | S100 calcium binding protein A14 | 0.27 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL7A1 | collagen, type VII, alpha 1 | -2.97 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -2.44 |
| TRIM29 | tripartite motif containing 29 | -2.32 |
| TEN1 | TEN1 CST complex subunit | -2.24 |
| ANK2 | ankyrin 2, neuronal | -2.1 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -1.7 |
| NPHP3 | nephronophthisis 3 (adolescent) | -1.51 |
| CCDC110 | coiled-coil domain containing 110 | -1.48 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | -1.09 |
| TTN | titin | -0.97 |
| MYRF | myelin regulatory factor | -0.82 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.73 |
| KALRN | kalirin, RhoGEF kinase | -0.72 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | -0.69 |
| STYX | serine/threonine/tyrosine interacting protein | -0.68 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.68 |
| BLOC1S2 | biogenesis of lysosomal organelles complex-1, subunit 2 | -0.67 |
| LMO4 | LIM domain only 4 | -0.64 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.62 |
| YAE1 | YAE1 maturation factor of ABCE1 | -0.59 |
| BCO2 | beta-carotene oxygenase 2 | -0.59 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.57 |
| LAP3 | leucine aminopeptidase 3 | -0.55 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | -0.53 |
| DCHS1 | dachsous cadherin-related 1 | -0.53 |
| DDN | dendrin | -0.52 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.51 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | -0.51 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | -0.5 |
| FCHO1 | FCH domain only 1 | -0.44 |
| ESAM | endothelial cell adhesion molecule | -0.43 |
| ZNF652 | zinc finger protein 652 | -0.39 |
| GPATCH4 | G patch domain containing 4 | -0.39 |
| ZNF341 | zinc finger protein 341 | -0.39 |
| ZNF600 | zinc finger protein 600 | -0.38 |
| KCTD6 | potassium channel tetramerization domain containing 6 | -0.37 |
| NKAPD1 | NKAP domain containing 1 | -0.36 |
| SELENOW | selenoprotein W | -0.35 |
| SMIM26 | small integral membrane protein 26 | -0.35 |
| DALRD3 | DALR anticodon binding domain containing 3 | -0.35 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.35 |
| ABHD14A | abhydrolase domain containing 14A | -0.35 |
| TXNDC15 | thioredoxin domain containing 15 | -0.33 |
| SYN2 | synapsin II | -0.33 |
| ZNF121 | zinc finger protein 121 | -0.33 |
| S100PBP | S100P binding protein | -0.33 |
| ARL6IP4 | ADP-ribosylation factor-like 6 interacting protein 4 | -0.33 |
| ZDHHC23 | zinc finger, DHHC-type containing 23 | -0.33 |
| ASB1 | ankyrin repeat and SOCS box containing 1 | -0.33 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.32 |
| ABHD15 | abhydrolase domain containing 15 | -0.32 |
| BAIAP3 | BAI1-associated protein 3 | -0.32 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.32 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.31 |
| EYS | eyes shut homolog (Drosophila) | -0.31 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.3 |
| TRO | trophinin | -0.3 |
| H1-4 | H1.4 linker histone, cluster member | -0.29 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.29 |
| RCAN1 | regulator of calcineurin 1 | -0.29 |
| ACTL8 | actin-like 8 | -0.28 |
| FAT2 | FAT atypical cadherin 2 | -0.28 |
| LSM11 | LSM11, U7 small nuclear RNA associated | -0.28 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.28 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -0.28 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.28 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.27 |
| CEP44 | centrosomal protein 44kDa | -0.27 |
| SNX19 | sorting nexin 19 | -0.27 |
| SELENOH | selenoprotein H | -0.27 |
| H3-3A | H3.3 histone A | -0.27 |
| ENKD1 | enkurin domain containing 1 | -0.27 |
| RBL2 | retinoblastoma-like 2 | -0.27 |
| EGR1 | early growth response 1 | -0.27 |
| RAB30 | RAB30, member RAS oncogene family | -0.26 |
| UBE2F | ubiquitin-conjugating enzyme E2F (putative) | -0.26 |
| CLK2 | CDC-like kinase 2 | -0.26 |
| ZBTB4 | zinc finger and BTB domain containing 4 | -0.26 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | -0.26 |
| YBX3 | Y box binding protein 3 | -0.26 |
| CEP57 | centrosomal protein 57kDa | -0.26 |
| MTMR8 | myotubularin related protein 8 | -0.25 |
| FAM133A | family with sequence similarity 133, member A | -0.25 |
| TRIM39 | tripartite motif containing 39 | -0.25 |
| ADAM22 | ADAM metallopeptidase domain 22 | -0.24 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | -0.24 |
| ZNF566 | zinc finger protein 566 | -0.24 |
| ZNF555 | zinc finger protein 555 | -0.24 |
| CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1 | -0.24 |
| HIST1H1T | histone cluster 1, H1t | -0.24 |
| GPX4 | glutathione peroxidase 4 | -0.24 |
| KCTD20 | potassium channel tetramerization domain containing 20 | -0.24 |
| ZNF525 | zinc finger protein 525 | -0.24 |
| ARHGEF19 | Rho guanine nucleotide exchange factor (GEF) 19 | -0.24 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.23 |
| BMP8A | bone morphogenetic protein 8a | -0.23 |
| ERCC6 | excision repair cross-complementation group 6 | -0.23 |
| DEPDC7 | DEP domain containing 7 | -0.23 |
| GORAB | golgin, RAB6-interacting | -0.23 |
| FBRSL1 | fibrosin-like 1 | -0.23 |
