| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.13202 |
| TMSB10 | thymosin beta 10 | 0.129811 |
| RPS12 | ribosomal protein S12 | 0.0945869 |
| RPS3 | ribosomal protein S3 | 0.0844312 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.061084 |
| DST | dystonin | 0.0550194 |
| RPS2 | ribosomal protein S2 | 0.052744 |
| RPL23 | ribosomal protein L23 | 0.0492544 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0481073 |
| RPS29 | ribosomal protein S29 | 0.0472116 |
| RPL36 | ribosomal protein L36 | 0.045048 |
| RPS19 | ribosomal protein S19 | 0.0447008 |
| RPL37A | ribosomal protein L37a | 0.0438112 |
| RPS4X | ribosomal protein S4, X-linked | 0.0410298 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0401711 |
| MKI67 | marker of proliferation Ki-67 | 0.0392029 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0364611 |
| EZR | ezrin | 0.0358637 |
| RPS11 | ribosomal protein S11 | 0.0350711 |
| RPS17 | ribosomal protein S17 | 0.0349524 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0347382 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0345889 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0345045 |
| ZNF292 | zinc finger protein 292 | 0.0338307 |
| PCBP2 | poly(rC) binding protein 2 | 0.0331444 |
| SMYD3 | SET and MYND domain containing 3 | 0.0320754 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0316504 |
| TPI1 | triosephosphate isomerase 1 | 0.0316085 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0315917 |
| RPS27 | ribosomal protein S27 | 0.0312063 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0311642 |
| RPS8 | ribosomal protein S8 | 0.0308812 |
| NEK7 | NIMA-related kinase 7 | 0.0306917 |
| CENPE | centromere protein E, 312kDa | 0.0305505 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0298421 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0295076 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0293134 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0290861 |
| CEP192 | centrosomal protein 192kDa | 0.0286002 |
| NEBL | nebulette | 0.0283918 |
| RPL37 | ribosomal protein L37 | 0.0282873 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0277694 |
| CENPF | centromere protein F, 350/400kDa | 0.0265517 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0259197 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0257079 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.0254356 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0252404 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0245961 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0245955 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0245917 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0245072 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0239495 |
| MRPL51 | mitochondrial ribosomal protein L51 | 0.0239072 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0238165 |
| RPL36A | ribosomal protein L36a | 0.0236666 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0231624 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0230286 |
| TBK1 | TANK-binding kinase 1 | 0.0228919 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0224661 |
| KIF18B | kinesin family member 18B | 0.0224333 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0222635 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0222152 |
| RPS26 | ribosomal protein S26 | 0.022019 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0220138 |
| PCM1 | pericentriolar material 1 | 0.0218704 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0216214 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0215124 |
| ENAH | enabled homolog (Drosophila) | 0.0215011 |
| RACK1 | receptor for activated C kinase 1 | 0.0213022 |
| ZNF146 | zinc finger protein 146 | 0.0210508 |
| SP3 | Sp3 transcription factor | 0.0210165 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0209457 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0207292 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0206221 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0206051 |
| SET | SET nuclear proto-oncogene | 0.0205234 |
| CDK19 | cyclin-dependent kinase 19 | 0.0205212 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0204829 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0203391 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0203158 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0202842 |
| RPL26 | ribosomal protein L26 | 0.0201601 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0201308 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.020123 |
| NCOA6 | nuclear receptor coactivator 6 | 0.020101 |
| EDARADD | EDAR-associated death domain | 0.020012 |
| TPM3 | tropomyosin 3 | 0.0199324 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0198754 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.019875 |
| MSH6 | mutS homolog 6 | 0.0197386 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0196692 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0196153 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0196024 |
| RBM25 | RNA binding motif protein 25 | 0.0195717 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0192076 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0190486 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0189716 |
| RPS6 | ribosomal protein S6 | 0.0189701 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.018873 |
| THOC2 | THO complex 2 | 0.0186895 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.245237 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177918 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.133521 |
| MMP12 | matrix metallopeptidase 12 | -0.0961943 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0953934 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0907019 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0891317 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0877371 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0753567 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0736331 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733198 |
| HMGA2 | high mobility group AT-hook 2 | -0.0680754 |
| EHBP1 | EH domain binding protein 1 | -0.0636165 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0632995 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0572026 |
| ZNF804A | zinc finger protein 804A | -0.0568053 |
| PCDH7 | protocadherin 7 | -0.053041 |
| ASPH | aspartate beta-hydroxylase | -0.0525509 |
| ACTG1 | actin gamma 1 | -0.0521122 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0516911 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0515365 |
| HMGA1 | high mobility group AT-hook 1 | -0.0452523 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0446742 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0443266 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0442314 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0441397 |
| H1-0 | H1.0 linker histone | -0.0440437 |
| INTS6 | integrator complex subunit 6 | -0.0437603 |
| HDAC9 | histone deacetylase 9 | -0.0433561 |
| AHNAK | AHNAK nucleoprotein | -0.0431976 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0420287 |
| CLDN1 | claudin 1 | -0.0400376 |
| VDAC1 | voltage-dependent anion channel 1 | -0.039502 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0392889 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0391716 |
| CANX | calnexin | -0.0387002 |
| CCND1 | cyclin D1 | -0.0372775 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0370238 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0348425 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0329526 |
| RPLP0 | ribosomal protein, large, P0 | -0.0328167 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0325021 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0315354 |
| USP53 | ubiquitin specific peptidase 53 | -0.0302287 |
| RTN3 | reticulon 3 | -0.0300286 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.029647 |
| RPL38 | ribosomal protein L38 | -0.0295669 |
| PTMA | prothymosin, alpha | -0.0294488 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0291827 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0290712 |
| LMO7 | LIM domain 7 | -0.0290403 |
| PCDH9 | protocadherin 9 | -0.029029 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0288967 |
| KLF6 | Kruppel-like factor 6 | -0.0288036 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0287416 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0279823 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0277049 |
| ZNF638 | zinc finger protein 638 | -0.027223 |
| JMJD1C | jumonji domain containing 1C | -0.027028 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0268325 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0268096 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0267223 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0263314 |
| HMGB1 | high mobility group box 1 | -0.0262951 |
| NABP1 | nucleic acid binding protein 1 | -0.0260366 |
| RBM39 | RNA binding motif protein 39 | -0.0259721 |
| RASAL2 | RAS protein activator like 2 | -0.0259355 |
| CDK6 | cyclin-dependent kinase 6 | -0.0257852 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0256788 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0256137 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0250713 |
| UBC | ubiquitin C | -0.0248926 |
| TPM4 | tropomyosin 4 | -0.0246991 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0246255 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0243714 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0242575 |
| DTNA | dystrobrevin, alpha | -0.0239894 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0238348 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0235894 |
| LRRC23 | leucine rich repeat containing 23 | -0.0235071 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0234403 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0232908 |
| HOMER1 | homer scaffolding protein 1 | -0.0232136 |
| BRCA1 | breast cancer 1, early onset | -0.0229808 |
| GOLGB1 | golgin B1 | -0.0229429 |
| GNAS | GNAS complex locus | -0.0229426 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.022755 |
| TUBA1B | tubulin, alpha 1b | -0.0226787 |
| SRP72 | signal recognition particle 72kDa | -0.0226531 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0226336 |
| TFG | TRK-fused gene | -0.0225951 |
| CAVIN1 | caveolae associated protein 1 | -0.0225208 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.022287 |
| RPL6 | ribosomal protein L6 | -0.0222833 |
| PARK7 | parkinson protein 7 | -0.0221839 |
| ADIPOR2 | adiponectin receptor 2 | -0.022129 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0219202 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0218109 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0216201 |
| YME1L1 | YME1-like 1 ATPase | -0.021234 |
