| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.101659 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0817816 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0776905 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0766707 |
| NDRG1 | N-myc downstream regulated 1 | 0.0751322 |
| LDHA | lactate dehydrogenase A | 0.0678012 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0615377 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0532022 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0512323 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0493813 |
| FNDC3B | fibronectin type III domain containing 3B | 0.046554 |
| GOLGB1 | golgin B1 | 0.046254 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0453366 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0451366 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0450203 |
| EZR | ezrin | 0.0436033 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.042315 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0411475 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0403161 |
| TOB1 | transducer of ERBB2, 1 | 0.0385538 |
| DSPP | dentin sialophosphoprotein | 0.0377711 |
| MORF4L2 | mortality factor 4 like 2 | 0.0376345 |
| LMO7 | LIM domain 7 | 0.0369528 |
| IFNGR1 | interferon gamma receptor 1 | 0.0369139 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0355226 |
| WDR45B | WD repeat domain 45B | 0.0351036 |
| EHF | ets homologous factor | 0.0337949 |
| CANX | calnexin | 0.0322842 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0314875 |
| NPSR1 | neuropeptide S receptor 1 | 0.0313028 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0303829 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0295019 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.029425 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0292107 |
| CLTC | clathrin, heavy chain (Hc) | 0.0291731 |
| RREB1 | ras responsive element binding protein 1 | 0.0284006 |
| PTEN | phosphatase and tensin homolog | 0.0281914 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0275048 |
| ARRDC3 | arrestin domain containing 3 | 0.0274748 |
| MLEC | malectin | 0.0272136 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0270198 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.026807 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0260918 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0255855 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0250294 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0249351 |
| ABHD2 | abhydrolase domain containing 2 | 0.024353 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0243218 |
| STK39 | serine threonine kinase 39 | 0.0241023 |
| THOC2 | THO complex 2 | 0.0239118 |
| KRT18 | keratin 18, type I | 0.0236172 |
| CMIP | c-Maf inducing protein | 0.023542 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0234684 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.023368 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0231499 |
| KIF16B | kinesin family member 16B | 0.0231465 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0230028 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0229501 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0226681 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0222437 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0219186 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.021896 |
| ENO1 | enolase 1, (alpha) | 0.0217386 |
| TMEM123 | transmembrane protein 123 | 0.0216384 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0215201 |
| JUN | jun proto-oncogene | 0.0215068 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0214644 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0213859 |
| MEF2A | myocyte enhancer factor 2A | 0.0211892 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0209798 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0206293 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0206192 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0204911 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0204289 |
| GOLGA4 | golgin A4 | 0.0203747 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0202858 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0202734 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0202343 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.01995 |
| SFTPA2 | surfactant protein A2 | 0.0196441 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0191715 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0190384 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0188392 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0188324 |
| ABLIM1 | actin binding LIM protein 1 | 0.0186934 |
| HELZ | helicase with zinc finger | 0.0186548 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0186516 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0186258 |
| SEC24D | SEC24 family member D | 0.0183244 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0181821 |
| CALU | calumenin | 0.0181746 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0181586 |
| RACK1 | receptor for activated C kinase 1 | 0.0181247 |
| MED15 | mediator complex subunit 15 | 0.0180899 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.018011 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0179637 |
| ARF4 | ADP-ribosylation factor 4 | 0.0177763 |
| NIPSNAP2 | nipsnap homolog 2 | 0.017746 |
| HYOU1 | hypoxia up-regulated 1 | 0.0176652 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0173075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.139352 |
| HLA-B | major histocompatibility complex, class I, B | -0.104121 |
| INTS6 | integrator complex subunit 6 | -0.103138 |
| LCN2 | lipocalin 2 | -0.100208 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0902878 |
| B2M | beta-2-microglobulin | -0.0871748 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0846191 |
| VCL | vinculin | -0.0843532 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0805944 |
| RPL35A | ribosomal protein L35a | -0.0776361 |
| TMSB10 | thymosin beta 10 | -0.0693974 |
| EGR1 | early growth response 1 | -0.0688656 |
| RNF213 | ring finger protein 213 | -0.0685912 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0664198 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0646499 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0623044 |
| AHI1 | Abelson helper integration site 1 | -0.0604426 |
| ANXA2 | annexin A2 | -0.0595793 |
| RIGI | RNA sensor RIG-I | -0.0588972 |
| RPLP1 | ribosomal protein, large, P1 | -0.0587403 |
| MT2A | metallothionein 2A | -0.0580996 |
| SP100 | SP100 nuclear antigen | -0.0569598 |
| FTL | ferritin, light polypeptide | -0.0563856 |
| MAP7 | microtubule-associated protein 7 | -0.0537911 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0522379 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0517573 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0491374 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0479639 |
| ACTN4 | actinin, alpha 4 | -0.0442968 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0428216 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0426426 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0420313 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0418684 |
| RPL19 | ribosomal protein L19 | -0.0417889 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0414648 |
| HLA-C | major histocompatibility complex, class I, C | -0.041352 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0399679 |
| RPS19 | ribosomal protein S19 | -0.0397226 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0392292 |
| RPL11 | ribosomal protein L11 | -0.0392242 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0391546 |
| RPS24 | ribosomal protein S24 | -0.0387691 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0387169 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0382604 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0381521 |
| STK24 | serine/threonine kinase 24 | -0.0380412 |
| MYO1E | myosin IE | -0.0380016 |
| MT1X | metallothionein 1X | -0.037846 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0373576 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0370633 |
| ATXN1 | ataxin 1 | -0.0369833 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0364317 |
| ETV6 | ets variant 6 | -0.0360717 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0356763 |
| FOXP1 | forkhead box P1 | -0.0354408 |
| RPS6 | ribosomal protein S6 | -0.0354074 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0345819 |
| RPL23 | ribosomal protein L23 | -0.0344261 |
| VMP1 | vacuole membrane protein 1 | -0.0338708 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0338389 |
| S100A10 | S100 calcium binding protein A10 | -0.033676 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.033445 |
| NCKAP5 | NCK-associated protein 5 | -0.0333571 |
| PRKCA | protein kinase C, alpha | -0.0329381 |
| MX2 | MX dynamin-like GTPase 2 | -0.0327339 |
| PERP | PERP, TP53 apoptosis effector | -0.0326338 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0326169 |
| PLSCR1 | phospholipid scramblase 1 | -0.0325791 |
| H3-3B | H3.3 histone B | -0.0324743 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0320464 |
| H1-0 | H1.0 linker histone | -0.0318799 |
| PTMA | prothymosin, alpha | -0.0315854 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0315743 |
| JAK1 | Janus kinase 1 | -0.0312118 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.030896 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.030229 |
| ERBIN | erbb2 interacting protein | -0.0299384 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0298417 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0298143 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0296185 |
| RPL31 | ribosomal protein L31 | -0.0296037 |
| RPL12 | ribosomal protein L12 | -0.029575 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0295591 |
| RPL37 | ribosomal protein L37 | -0.0295558 |
| XAF1 | XIAP associated factor 1 | -0.0294427 |
| SMYD3 | SET and MYND domain containing 3 | -0.0291447 |
| RNF43 | ring finger protein 43 | -0.0289807 |
| HLA-A | major histocompatibility complex, class I, A | -0.0288256 |
| TJP1 | tight junction protein 1 | -0.0288211 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0287874 |
| RAD51B | RAD51 paralog B | -0.0286382 |
| CLDN4 | claudin 4 | -0.0283411 |
| RPL28 | ribosomal protein L28 | -0.028011 |
| ATP11A | ATPase, class VI, type 11A | -0.0279591 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0276622 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0275976 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0274293 |
| NF1 | neurofibromin 1 | -0.0269585 |
| YAP1 | Yes-associated protein 1 | -0.0269241 |
| RPL34 | ribosomal protein L34 | -0.0267905 |
