| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT18 | keratin 18, type I | 0.147 |
| PTMA | prothymosin, alpha | 0.123523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105406 |
| EREG | epiregulin | 0.0957771 |
| LDHA | lactate dehydrogenase A | 0.0921615 |
| NDRG1 | N-myc downstream regulated 1 | 0.0913587 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0897632 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0882331 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0874329 |
| FAM13A | family with sequence similarity 13, member A | 0.0787019 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0755939 |
| FLNB | filamin B, beta | 0.0752644 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0699404 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0697005 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0614552 |
| RREB1 | ras responsive element binding protein 1 | 0.0596002 |
| TXNIP | thioredoxin interacting protein | 0.0573511 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0567185 |
| RNF145 | ring finger protein 145 | 0.0562549 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.053503 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0514604 |
| NUP58 | nucleoporin 58 | 0.0503597 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0488667 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0479455 |
| EZR | ezrin | 0.0479359 |
| EHF | ets homologous factor | 0.0467997 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0458737 |
| ANXA2 | annexin A2 | 0.0453248 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0447232 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0444759 |
| CCNL1 | cyclin L1 | 0.0442535 |
| GOLGA4 | golgin A4 | 0.0437344 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0435154 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0435146 |
| ENO1 | enolase 1, (alpha) | 0.0418008 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0407917 |
| MORF4L2 | mortality factor 4 like 2 | 0.0406969 |
| RPS2 | ribosomal protein S2 | 0.0406196 |
| KIF5B | kinesin family member 5B | 0.0402761 |
| ZNF292 | zinc finger protein 292 | 0.040169 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0397629 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0393568 |
| LRRC1 | leucine rich repeat containing 1 | 0.0387758 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0385332 |
| MLEC | malectin | 0.0383845 |
| MED13L | mediator complex subunit 13-like | 0.0383389 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0383213 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0381534 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0380917 |
| WDR45B | WD repeat domain 45B | 0.0375231 |
| DSPP | dentin sialophosphoprotein | 0.0371625 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0370825 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0368117 |
| RBM39 | RNA binding motif protein 39 | 0.03664 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0365766 |
| TFG | TRK-fused gene | 0.036304 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0362214 |
| TMSB4X | thymosin beta 4, X-linked | 0.0361995 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0355567 |
| AREG | amphiregulin | 0.035465 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0352286 |
| NEK7 | NIMA-related kinase 7 | 0.0352036 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.035112 |
| RAB6A | RAB6A, member RAS oncogene family | 0.035044 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0349908 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0343646 |
| YTHDC1 | YTH domain containing 1 | 0.0342863 |
| RLF | rearranged L-myc fusion | 0.0342167 |
| RPS3 | ribosomal protein S3 | 0.0338909 |
| HELZ | helicase with zinc finger | 0.0336898 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0334979 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0331121 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0330059 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0329034 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0327644 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0317436 |
| SETD5 | SET domain containing 5 | 0.0312327 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0308753 |
| RPS12 | ribosomal protein S12 | 0.0306264 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0304562 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0304164 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0303148 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0300593 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0299763 |
| WDR43 | WD repeat domain 43 | 0.0299345 |
| COPA | coatomer protein complex, subunit alpha | 0.0298962 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.029667 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293261 |
| SPAG9 | sperm associated antigen 9 | 0.0292983 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.029198 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0288314 |
| MXD1 | MAX dimerization protein 1 | 0.0288289 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0288267 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0288201 |
| FOSL1 | FOS-like antigen 1 | 0.0286341 |
| SET | SET nuclear proto-oncogene | 0.028555 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0285066 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.028428 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0282937 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0282716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.147645 |
| TMSB10 | thymosin beta 10 | -0.098178 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0885269 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0865441 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0796946 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0781011 |
| RPS19 | ribosomal protein S19 | -0.0748795 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.073001 |
| RPLP1 | ribosomal protein, large, P1 | -0.0727759 |
| SMYD3 | SET and MYND domain containing 3 | -0.0727137 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0719819 |
| CADPS | Ca++-dependent secretion activator | -0.06882 |
| MT2A | metallothionein 2A | -0.0678426 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0625572 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0620585 |
| FOXP1 | forkhead box P1 | -0.060163 |
| NPSR1 | neuropeptide S receptor 1 | -0.0595836 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0588652 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0553158 |
| ATXN1 | ataxin 1 | -0.0535461 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0533116 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0529714 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0512885 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0494932 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0458182 |
| MT1X | metallothionein 1X | -0.045097 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0443277 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0437842 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.043698 |
| RPL34 | ribosomal protein L34 | -0.0432613 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0428328 |
| ONECUT3 | one cut homeobox 3 | -0.0426115 |
| ASPH | aspartate beta-hydroxylase | -0.0423171 |
| RPL35A | ribosomal protein L35a | -0.0419193 |
| POF1B | premature ovarian failure, 1B | -0.041774 |
| RPS21 | ribosomal protein S21 | -0.0417273 |
| FHIT | fragile histidine triad | -0.0413643 |
| SLC35F3 | solute carrier family 35, member F3 | -0.04115 |
| AHNAK | AHNAK nucleoprotein | -0.0406913 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0405284 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0402318 |
| FTL | ferritin, light polypeptide | -0.0399004 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0394815 |
| RPL19 | ribosomal protein L19 | -0.0390222 |
| RPL32 | ribosomal protein L32 | -0.0389858 |
| RPL12 | ribosomal protein L12 | -0.0386816 |
| MYO1E | myosin IE | -0.0383029 |
| H1-0 | H1.0 linker histone | -0.0382161 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0368007 |
| RPL36 | ribosomal protein L36 | -0.0364997 |
| MECOM | MDS1 and EVI1 complex locus | -0.0347704 |
| RRBP1 | ribosome binding protein 1 | -0.034187 |
| NFIA | nuclear factor I/A | -0.0340031 |
| MT1E | metallothionein 1E | -0.0339756 |
| EGFR | epidermal growth factor receptor | -0.0336412 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0334525 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0329006 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0328819 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325633 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0315861 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0313229 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.031281 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0311466 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0310177 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.030613 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.03061 |
| FAT1 | FAT atypical cadherin 1 | -0.0305628 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.029815 |
| RAD51B | RAD51 paralog B | -0.0289888 |
| RPLP0 | ribosomal protein, large, P0 | -0.0289473 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.028711 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.028649 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0285445 |
| S100A14 | S100 calcium binding protein A14 | -0.0284402 |
| VCL | vinculin | -0.0282172 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0281996 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0279696 |
| CD44 | CD44 molecule (Indian blood group) | -0.0278766 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0278144 |
| ACTN4 | actinin, alpha 4 | -0.0276295 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0275931 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0274917 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.027483 |
| ACTG1 | actin gamma 1 | -0.0273621 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0269947 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0269753 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0268519 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0264648 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0263918 |
| PTEN | phosphatase and tensin homolog | -0.026387 |
| RPL28 | ribosomal protein L28 | -0.0259439 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0255688 |
| PALLD | palladin, cytoskeletal associated protein | -0.0255681 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0252569 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0250609 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0249344 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0248805 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0248771 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0248245 |
