| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0785026 |
| USP34 | ubiquitin specific peptidase 34 | 0.0626301 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0588091 |
| MT2A | metallothionein 2A | 0.0539834 |
| PCBP2 | poly(rC) binding protein 2 | 0.051682 |
| NAV2 | neuron navigator 2 | 0.0512732 |
| ZNF292 | zinc finger protein 292 | 0.0490144 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0407294 |
| RPS3 | ribosomal protein S3 | 0.0389824 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.03699 |
| EGFR | epidermal growth factor receptor | 0.0354383 |
| FLNB | filamin B, beta | 0.0338238 |
| VEGFA | vascular endothelial growth factor A | 0.0325351 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0323401 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0316156 |
| ANGPTL4 | angiopoietin-like 4 | 0.0314967 |
| SIK3 | SIK family kinase 3 | 0.0309652 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0309538 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0305929 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0305338 |
| ATP5MC2 | ATP synthase membrane subunit c locus 2 | 0.0293594 |
| RPS12 | ribosomal protein S12 | 0.0283095 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0281979 |
| RPS2 | ribosomal protein S2 | 0.0281179 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0275139 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0272865 |
| RPL37A | ribosomal protein L37a | 0.0258343 |
| RPS17 | ribosomal protein S17 | 0.0257151 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0254146 |
| ATP13A3 | ATPase type 13A3 | 0.0253346 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0253118 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0250652 |
| STK38L | serine/threonine kinase 38 like | 0.024676 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0244238 |
| RAD51B | RAD51 paralog B | 0.0232388 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0231989 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0222104 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0217815 |
| TBK1 | TANK-binding kinase 1 | 0.0214969 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0214395 |
| IL1R1 | interleukin 1 receptor, type I | 0.02104 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0209282 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0208677 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0207497 |
| PTEN | phosphatase and tensin homolog | 0.0207291 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0197606 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0195682 |
| EHBP1 | EH domain binding protein 1 | 0.0194604 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0192831 |
| UBE3A | ubiquitin protein ligase E3A | 0.0192828 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0192496 |
| MEF2D | myocyte enhancer factor 2D | 0.0192057 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0191676 |
| PCM1 | pericentriolar material 1 | 0.0191466 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0190598 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0189148 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0189068 |
| SMAD4 | SMAD family member 4 | 0.0188734 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0188558 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0186227 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0186124 |
| RPS4X | ribosomal protein S4, X-linked | 0.0185954 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0185823 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0183857 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.018314 |
| SFTPA2 | surfactant protein A2 | 0.0182816 |
| GOLGA2 | golgin A2 | 0.0182811 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.018279 |
| RPL36 | ribosomal protein L36 | 0.0182587 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0182499 |
| RPS19 | ribosomal protein S19 | 0.0182409 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0181096 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0181079 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0180509 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0179721 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0178713 |
| PGM3 | phosphoglucomutase 3 | 0.0177648 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0174439 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0173871 |
| MKI67 | marker of proliferation Ki-67 | 0.0171492 |
| MORF4L2 | mortality factor 4 like 2 | 0.0170953 |
| SLTM | SAFB-like, transcription modulator | 0.0170739 |
| WDR26 | WD repeat domain 26 | 0.0170385 |
| YLPM1 | YLP motif containing 1 | 0.0169564 |
| ARF4 | ADP-ribosylation factor 4 | 0.0168963 |
| RPL23 | ribosomal protein L23 | 0.0167973 |
| ACTN4 | actinin, alpha 4 | 0.0167941 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0165664 |
| EEA1 | early endosome antigen 1 | 0.0164915 |
| MYO1B | myosin IB | 0.0164764 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.016439 |
| PNN | pinin, desmosome associated protein | 0.0163404 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0163197 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0162344 |
| TGM2 | transglutaminase 2 | 0.0161492 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0160954 |
| PEX13 | peroxisomal biogenesis factor 13 | 0.0160736 |
| ACTN1 | actinin, alpha 1 | 0.0158909 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0155721 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0155576 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.280362 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.206783 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.160379 |
| LOX | lysyl oxidase | -0.132914 |
| CDH13 | cadherin 13 | -0.118048 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109228 |
| VIM | vimentin | -0.106909 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.106702 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0932932 |
| STC1 | stanniocalcin 1 | -0.0886125 |
| FN1 | fibronectin 1 | -0.0863834 |
| PTMA | prothymosin, alpha | -0.0807241 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0806421 |
| HMGA2 | high mobility group AT-hook 2 | -0.0760798 |
| FTL | ferritin, light polypeptide | -0.073905 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0734814 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0722843 |
| RBM39 | RNA binding motif protein 39 | -0.0713598 |
| GLCCI1 | glucocorticoid induced 1 | -0.0665849 |
| IER3 | immediate early response 3 | -0.0661481 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0653336 |
| NRG1 | neuregulin 1 | -0.0643629 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0638295 |
| CANX | calnexin | -0.0628168 |
| H1-0 | H1.0 linker histone | -0.0626263 |
| AHNAK | AHNAK nucleoprotein | -0.0625106 |
| MTSS1 | metastasis suppressor 1 | -0.0622944 |
| EFNA5 | ephrin-A5 | -0.0614237 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0612439 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0598206 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0597641 |
| RPLP0 | ribosomal protein, large, P0 | -0.0589004 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0585468 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0527446 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0524569 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0520106 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0519262 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0513794 |
| TMEM263 | transmembrane protein 263 | -0.0508062 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0500039 |
| RPS24 | ribosomal protein S24 | -0.0488562 |
| FAM13A | family with sequence similarity 13, member A | -0.0488099 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0486143 |
| RAI14 | retinoic acid induced 14 | -0.0484894 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0483634 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0475259 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0472453 |
| SP100 | SP100 nuclear antigen | -0.0470305 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.046852 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0467111 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0466705 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0466576 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0465456 |
| S100A6 | S100 calcium binding protein A6 | -0.0464105 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.045906 |
| NUMB | numb homolog (Drosophila) | -0.0457407 |
| TMSB4X | thymosin beta 4, X-linked | -0.0457078 |
| FBN1 | fibrillin 1 | -0.0442973 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0442772 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.043859 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0431302 |
| FAM20C | family with sequence similarity 20, member C | -0.0423587 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0416503 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0402628 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0402258 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0398287 |
| OGA | O-GlcNAcase | -0.0395725 |
| GNAS | GNAS complex locus | -0.0393989 |
| PARD3 | par-3 family cell polarity regulator | -0.0387753 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.03823 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0380377 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0379768 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0374313 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0370873 |
| RPS21 | ribosomal protein S21 | -0.0367975 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366183 |
| ANXA2 | annexin A2 | -0.0363895 |
| ASPH | aspartate beta-hydroxylase | -0.0361383 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0359208 |
| VDAC1 | voltage-dependent anion channel 1 | -0.035601 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0350995 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0349056 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0348942 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0343147 |
| VCL | vinculin | -0.0342695 |
| MECOM | MDS1 and EVI1 complex locus | -0.0339989 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0339158 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0338763 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0336104 |
| NAV3 | neuron navigator 3 | -0.0334805 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0332737 |
| RND3 | Rho family GTPase 3 | -0.0331645 |
| GOLGA4 | golgin A4 | -0.0328426 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0326886 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0324091 |
| RIGI | RNA sensor RIG-I | -0.0321438 |
| NTN4 | netrin 4 | -0.0320965 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0317693 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0316573 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0316167 |
