| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0791336 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0741831 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0732019 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0721121 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0699806 |
| TES | testin LIM domain protein | 0.0624375 |
| SUCO | SUN domain containing ossification factor | 0.0619123 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0618576 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.060675 |
| WDR45B | WD repeat domain 45B | 0.0594395 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0587186 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0577797 |
| NUP58 | nucleoporin 58 | 0.0575946 |
| TXNRD1 | thioredoxin reductase 1 | 0.0571478 |
| ATXN1 | ataxin 1 | 0.0570328 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.056696 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0564144 |
| PRELID2 | PRELI domain containing 2 | 0.0558857 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0555001 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0552726 |
| FMNL2 | formin-like 2 | 0.0548979 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0532637 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0528038 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.05227 |
| MORF4L2 | mortality factor 4 like 2 | 0.0520886 |
| HDLBP | high density lipoprotein binding protein | 0.0512286 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0512253 |
| ACTN1 | actinin, alpha 1 | 0.0511928 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.050235 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0491925 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0489817 |
| DENND5A | DENN/MADD domain containing 5A | 0.0487501 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0485591 |
| TUFT1 | tuftelin 1 | 0.0481171 |
| TJP1 | tight junction protein 1 | 0.0479779 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0462854 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0451431 |
| KLF6 | Kruppel-like factor 6 | 0.045031 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0441849 |
| TENM3 | teneurin transmembrane protein 3 | 0.0438791 |
| NEBL | nebulette | 0.0438255 |
| SNX9 | sorting nexin 9 | 0.0436572 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0434965 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0431606 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0430902 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0430535 |
| MATR3 | matrin 3 | 0.0430166 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0429622 |
| SNX14 | sorting nexin 14 | 0.0429455 |
| CLTC | clathrin, heavy chain (Hc) | 0.0428876 |
| VMP1 | vacuole membrane protein 1 | 0.042833 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0419885 |
| KIF5B | kinesin family member 5B | 0.0419493 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0417922 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0415052 |
| AHNAK | AHNAK nucleoprotein | 0.0409857 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0404293 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.040301 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0400106 |
| SEPTIN7 | septin 7 | 0.0398067 |
| ANKRD13C | ankyrin repeat domain 13C | 0.0397609 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0397005 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0394817 |
| AFDN | afadin, adherens junction formation factor | 0.0393543 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0392115 |
| NCKAP1 | NCK-associated protein 1 | 0.0391626 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0386917 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0385927 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0384316 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0382553 |
| RBM26 | RNA binding motif protein 26 | 0.0366555 |
| NEK7 | NIMA-related kinase 7 | 0.0366116 |
| ANLN | anillin, actin binding protein | 0.0364072 |
| MED13 | mediator complex subunit 13 | 0.0362104 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0361427 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0361391 |
| RHEB | Ras homolog enriched in brain | 0.0359983 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0355077 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.035388 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0349399 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0348336 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.034331 |
| ZNF292 | zinc finger protein 292 | 0.0342939 |
| ATF6 | activating transcription factor 6 | 0.0341674 |
| RNF145 | ring finger protein 145 | 0.0339819 |
| NOP58 | NOP58 ribonucleoprotein | 0.0338039 |
| MED13L | mediator complex subunit 13-like | 0.0335045 |
| MKI67 | marker of proliferation Ki-67 | 0.033464 |
| LDHA | lactate dehydrogenase A | 0.0329495 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0327955 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0324417 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0324167 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0323936 |
| EZR | ezrin | 0.0321386 |
| FBXO11 | F-box protein 11 | 0.0320972 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0318381 |
| SQSTM1 | sequestosome 1 | 0.0317018 |
| CNKSR3 | CNKSR family member 3 | 0.0314075 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0310493 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0310128 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.139186 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126141 |
| MT2A | metallothionein 2A | -0.121696 |
| FNDC3B | fibronectin type III domain containing 3B | -0.118321 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0975685 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0868213 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0853525 |
| CD44 | CD44 molecule (Indian blood group) | -0.0842477 |
| PTMA | prothymosin, alpha | -0.0839409 |
| ENO1 | enolase 1, (alpha) | -0.0783376 |
| AK1 | adenylate kinase 1 | -0.0781119 |
| IGF2 | insulin-like growth factor 2 | -0.0775021 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.076443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0764248 |
| RIGI | RNA sensor RIG-I | -0.0763484 |
| TMSB10 | thymosin beta 10 | -0.075699 |
| FTL | ferritin, light polypeptide | -0.0710441 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0705206 |
| ZNF638 | zinc finger protein 638 | -0.0687278 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0684061 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0678646 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.067359 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0672963 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0671694 |
| PRKCA | protein kinase C, alpha | -0.0645487 |
| CALU | calumenin | -0.0632547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0620723 |
| TMEM165 | transmembrane protein 165 | -0.0607082 |
| RPS21 | ribosomal protein S21 | -0.0599802 |
| RPS3 | ribosomal protein S3 | -0.0593777 |
| RPL19 | ribosomal protein L19 | -0.0586468 |
| METTL15 | methyltransferase like 15 | -0.0574307 |
| APP | amyloid beta (A4) precursor protein | -0.0554648 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0552435 |
| KYNU | kynureninase | -0.0550596 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.054324 |
| CANX | calnexin | -0.0535695 |
| JMJD1C | jumonji domain containing 1C | -0.0527814 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0524138 |
| HLA-B | major histocompatibility complex, class I, B | -0.0515109 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0509072 |
| OGA | O-GlcNAcase | -0.0508249 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0480836 |
| ASPH | aspartate beta-hydroxylase | -0.0479548 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0473911 |
| LAMB3 | laminin, beta 3 | -0.0455644 |
| WDR7 | WD repeat domain 7 | -0.0449519 |
| NDRG1 | N-myc downstream regulated 1 | -0.0448602 |
| TPI1 | triosephosphate isomerase 1 | -0.0439409 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0438552 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0433535 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0423089 |
| NME7 | NME/NM23 family member 7 | -0.042049 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0418749 |
| RPL34 | ribosomal protein L34 | -0.0417596 |
| RTN4 | reticulon 4 | -0.0416532 |
| SP100 | SP100 nuclear antigen | -0.0414377 |
| EHBP1 | EH domain binding protein 1 | -0.0414311 |
| TMSB4X | thymosin beta 4, X-linked | -0.0411623 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0408856 |
| FMN1 | formin 1 | -0.0399166 |
| SMYD3 | SET and MYND domain containing 3 | -0.0395119 |
| RPLP0 | ribosomal protein, large, P0 | -0.0394875 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0394148 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0392262 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0392046 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0390609 |
| RNF149 | ring finger protein 149 | -0.0389369 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0383055 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0382088 |
| B2M | beta-2-microglobulin | -0.0375417 |
| USP34 | ubiquitin specific peptidase 34 | -0.0373843 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.037321 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0370043 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.036194 |
| BRD2 | bromodomain containing 2 | -0.0358946 |
| ATOSA | atos homolog A | -0.0354109 |
| MTDH | metadherin | -0.0347883 |
| MXD1 | MAX dimerization protein 1 | -0.0343141 |
| S100A10 | S100 calcium binding protein A10 | -0.0340822 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0339401 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0334263 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0331557 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0325278 |
| RPL35A | ribosomal protein L35a | -0.0325204 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0321142 |
| SRP54 | signal recognition particle 54kDa | -0.0320622 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0320621 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0316486 |
| AFAP1 | actin filament associated protein 1 | -0.0314928 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0314871 |
| NPTN | neuroplastin | -0.0305676 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0303327 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0302846 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0299736 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0294131 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0291517 |
| LIMA1 | LIM domain and actin binding 1 | -0.0288018 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0287868 |
| PKM | pyruvate kinase, muscle | -0.0287205 |
