| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.116639 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.10828 |
| TMSB4X | thymosin beta 4, X-linked | 0.0967266 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0844641 |
| EZR | ezrin | 0.0706199 |
| LDHA | lactate dehydrogenase A | 0.0658999 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.061649 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0614206 |
| TXNRD1 | thioredoxin reductase 1 | 0.0560516 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0546207 |
| PKM | pyruvate kinase, muscle | 0.0527044 |
| PYGB | phosphorylase, glycogen; brain | 0.0504181 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0491383 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0444812 |
| RTN4 | reticulon 4 | 0.0434611 |
| ZNF292 | zinc finger protein 292 | 0.0422131 |
| NUP58 | nucleoporin 58 | 0.0391931 |
| ZNF217 | zinc finger protein 217 | 0.0391418 |
| PRELID2 | PRELI domain containing 2 | 0.0382654 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0378802 |
| SQSTM1 | sequestosome 1 | 0.0366569 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0364442 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0358939 |
| RPS2 | ribosomal protein S2 | 0.0356891 |
| AHNAK | AHNAK nucleoprotein | 0.0344897 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0344344 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0343148 |
| NCKAP1 | NCK-associated protein 1 | 0.034269 |
| TXNIP | thioredoxin interacting protein | 0.0335266 |
| RPS4X | ribosomal protein S4, X-linked | 0.0331558 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0329776 |
| APP | amyloid beta (A4) precursor protein | 0.031591 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298898 |
| MXI1 | MAX interactor 1, dimerization protein | 0.029222 |
| RACK1 | receptor for activated C kinase 1 | 0.0289842 |
| SMYD3 | SET and MYND domain containing 3 | 0.0283556 |
| MATR3 | matrin 3 | 0.0282134 |
| PLK2 | polo-like kinase 2 | 0.0281599 |
| CDC73 | cell division cycle 73 | 0.027998 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0276309 |
| ZNF608 | zinc finger protein 608 | 0.027503 |
| RBM39 | RNA binding motif protein 39 | 0.0269885 |
| DUSP4 | dual specificity phosphatase 4 | 0.026734 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0254595 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0253275 |
| SERINC1 | serine incorporator 1 | 0.0249192 |
| SPAG9 | sperm associated antigen 9 | 0.0247706 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.024369 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0242646 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0235306 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0235039 |
| CLTC | clathrin, heavy chain (Hc) | 0.0234622 |
| UBQLN1 | ubiquilin 1 | 0.0232718 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.023158 |
| ARRDC3 | arrestin domain containing 3 | 0.0228216 |
| PLPP3 | phospholipid phosphatase 3 | 0.0224314 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0222675 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0217737 |
| NBAS | neuroblastoma amplified sequence | 0.0217449 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0215079 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0212708 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0208971 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0208377 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0207897 |
| COG5 | component of oligomeric golgi complex 5 | 0.0207175 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0207168 |
| CCNL1 | cyclin L1 | 0.0207131 |
| CALU | calumenin | 0.0204163 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0203476 |
| PAPOLA | poly(A) polymerase alpha | 0.0202772 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0198508 |
| ANKRD12 | ankyrin repeat domain 12 | 0.019703 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0194378 |
| YAP1 | Yes-associated protein 1 | 0.0193895 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.019375 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0193077 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0190033 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.018748 |
| ANKRD10 | ankyrin repeat domain 10 | 0.018572 |
| MORF4L2 | mortality factor 4 like 2 | 0.018517 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0184115 |
| SNX9 | sorting nexin 9 | 0.0180063 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0179934 |
| RPL23 | ribosomal protein L23 | 0.0178937 |
| CRY1 | cryptochrome circadian clock 1 | 0.0178878 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0178138 |
| ECT2 | epithelial cell transforming 2 | 0.0177931 |
| RBM33 | RNA binding motif protein 33 | 0.0177622 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0177426 |
| KLF6 | Kruppel-like factor 6 | 0.0177159 |
| RYBP | RING1 and YY1 binding protein | 0.0175073 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0174571 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0173986 |
| DAPK3 | death-associated protein kinase 3 | 0.0170072 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0169889 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0168811 |
| ATP9B | ATPase, class II, type 9B | 0.0168383 |
| YEATS2 | YEATS domain containing 2 | 0.0168152 |
| PGK1 | phosphoglycerate kinase 1 | 0.016738 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.01653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.214055 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.204634 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.127368 |
| FOXP1 | forkhead box P1 | -0.123609 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.117796 |
| PTMA | prothymosin, alpha | -0.102583 |
| HDAC9 | histone deacetylase 9 | -0.0801445 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0755582 |
| BMP10 | bone morphogenetic protein 10 | -0.0730284 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0721295 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0716204 |
| NBEA | neurobeachin | -0.0691325 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0647198 |
| NFIA | nuclear factor I/A | -0.0564448 |
| VCL | vinculin | -0.0558144 |
| EFNA5 | ephrin-A5 | -0.0550227 |
| NAV2 | neuron navigator 2 | -0.054246 |
| EVI5 | ecotropic viral integration site 5 | -0.0533145 |
| CENPF | centromere protein F, 350/400kDa | -0.0531231 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0531156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527945 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0520857 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0487104 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0473584 |
| MKI67 | marker of proliferation Ki-67 | -0.0463555 |
| CUX1 | cut-like homeobox 1 | -0.0454944 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0448796 |
| DIAPH3 | diaphanous-related formin 3 | -0.0446749 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0423657 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0415472 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0393909 |
| PDE7B | phosphodiesterase 7B | -0.0390835 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0371375 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0366744 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0356953 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0347578 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0327189 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0316611 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0311991 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0309769 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0306753 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0299607 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299019 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.02981 |
| GLI3 | GLI family zinc finger 3 | -0.0297269 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0293619 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0278971 |
| BMP2K | BMP2 inducible kinase | -0.0276824 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0276498 |
| PFN1 | profilin 1 | -0.0274206 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0264089 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0263474 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0261174 |
| PKP4 | plakophilin 4 | -0.025981 |
| RPS6 | ribosomal protein S6 | -0.0257334 |
| RPL35A | ribosomal protein L35a | -0.0252833 |
| NEBL | nebulette | -0.0250215 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0248909 |
| FNDC3B | fibronectin type III domain containing 3B | -0.024715 |
| TJP1 | tight junction protein 1 | -0.0245344 |
| POTEF | POTE ankyrin domain family, member F | -0.0239203 |
| HJURP | Holliday junction recognition protein | -0.0235818 |
| ATXN2 | ataxin 2 | -0.0232895 |
| ANKRD17 | ankyrin repeat domain 17 | -0.023117 |
| ZNF609 | zinc finger protein 609 | -0.0228511 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0219858 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0218057 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0215915 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0210171 |
| GPATCH8 | G patch domain containing 8 | -0.0209906 |
| GPHN | gephyrin | -0.0208693 |
| MLIP | muscular LMNA-interacting protein | -0.0206926 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0206887 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0205622 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0203417 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0201185 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0200513 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0199511 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0198901 |
| PDE10A | phosphodiesterase 10A | -0.0198551 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0196641 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0192355 |
| ONECUT2 | one cut homeobox 2 | -0.0191209 |
| INTS6 | integrator complex subunit 6 | -0.0190303 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0189606 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.01883 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0186617 |
| DEK | DEK proto-oncogene | -0.0185957 |
| TPX2 | TPX2, microtubule-associated | -0.0185289 |
| MSI2 | musashi RNA-binding protein 2 | -0.0184357 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0183386 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0181113 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0180041 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.017991 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.01799 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179161 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0178232 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0177914 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0175448 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0175037 |
