| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.070531 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0657166 |
| FAM13A | family with sequence similarity 13, member A | 0.0573425 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0566075 |
| VEGFA | vascular endothelial growth factor A | 0.0543484 |
| ARRDC3 | arrestin domain containing 3 | 0.0524822 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0500087 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0474132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0465321 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0460214 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0430649 |
| B2M | beta-2-microglobulin | 0.0415811 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0408406 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0407305 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0403065 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0403015 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0396901 |
| CALR | calreticulin | 0.0380236 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0351199 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.034801 |
| PHF21A | PHD finger protein 21A | 0.034758 |
| FAM13B | family with sequence similarity 13, member B | 0.0341077 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0331986 |
| RAD51B | RAD51 paralog B | 0.0330223 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.032885 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0321791 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0320389 |
| MORF4L2 | mortality factor 4 like 2 | 0.0320352 |
| DSTN | destrin (actin depolymerizing factor) | 0.0316246 |
| MSN | moesin | 0.0312048 |
| CANX | calnexin | 0.0301875 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0298183 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0297855 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0295698 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0294131 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0289274 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.028913 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0283387 |
| RNF145 | ring finger protein 145 | 0.0281462 |
| RPS8 | ribosomal protein S8 | 0.0278957 |
| RACK1 | receptor for activated C kinase 1 | 0.0277593 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0271666 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0267938 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0265844 |
| FTL | ferritin, light polypeptide | 0.0260477 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259821 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0259669 |
| PDE8A | phosphodiesterase 8A | 0.0257333 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0255888 |
| GNAS | GNAS complex locus | 0.0254785 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0254602 |
| RNF216 | ring finger protein 216 | 0.0253832 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0253256 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0251733 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0248009 |
| SEM1 | SEM1 26S proteasome subunit | 0.0246794 |
| PTN | pleiotrophin | 0.0246728 |
| ARMC9 | armadillo repeat containing 9 | 0.0245254 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0244673 |
| SERINC1 | serine incorporator 1 | 0.0244438 |
| MCL1 | myeloid cell leukemia 1 | 0.0242179 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0241674 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0239805 |
| NDRG1 | N-myc downstream regulated 1 | 0.023952 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0239062 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0239061 |
| HYOU1 | hypoxia up-regulated 1 | 0.0238671 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0237994 |
| KIF5B | kinesin family member 5B | 0.0237083 |
| RAB18 | RAB18, member RAS oncogene family | 0.0236586 |
| RPL12 | ribosomal protein L12 | 0.0236371 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0234252 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0233092 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0232303 |
| PRKD3 | protein kinase D3 | 0.0231994 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0231477 |
| HDGF | hepatoma-derived growth factor | 0.0230637 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0230426 |
| NEMF | nuclear export mediator factor | 0.0229973 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0227499 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0226911 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0226094 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0225823 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0225659 |
| NRBP1 | nuclear receptor binding protein 1 | 0.022557 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0224643 |
| FLNB | filamin B, beta | 0.0224465 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0224318 |
| IL6 | interleukin 6 | 0.0222645 |
| FMNL2 | formin-like 2 | 0.0222546 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221947 |
| CCDC186 | coiled-coil domain containing 186 | 0.022192 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0221088 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0220136 |
| MEF2D | myocyte enhancer factor 2D | 0.022005 |
| NME7 | NME/NM23 family member 7 | 0.021967 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0219132 |
| TMEM167A | transmembrane protein 167A | 0.0215856 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0214633 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0211091 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.165516 |
| COL6A3 | collagen, type VI, alpha 3 | -0.143524 |
| HLA-B | major histocompatibility complex, class I, B | -0.130307 |
| TMSB10 | thymosin beta 10 | -0.125597 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123579 |
| LOX | lysyl oxidase | -0.110429 |
| GLIS3 | GLIS family zinc finger 3 | -0.084663 |
| AHNAK | AHNAK nucleoprotein | -0.0807854 |
| HMGA2 | high mobility group AT-hook 2 | -0.0784861 |
| CALD1 | caldesmon 1 | -0.0782081 |
| VCL | vinculin | -0.0736738 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0706622 |
| CDK6 | cyclin-dependent kinase 6 | -0.0706617 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0688728 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0655059 |
| SRPK2 | SRSF protein kinase 2 | -0.0633503 |
| LOXL2 | lysyl oxidase-like 2 | -0.0629477 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0616899 |
| MAP1B | microtubule-associated protein 1B | -0.0589845 |
| HIP1 | huntingtin interacting protein 1 | -0.0577494 |
| OGA | O-GlcNAcase | -0.0570099 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0543707 |
| RAI14 | retinoic acid induced 14 | -0.05393 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0538785 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0535029 |
| PRSS23 | protease, serine, 23 | -0.0533174 |
| RASAL2 | RAS protein activator like 2 | -0.0533158 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0520355 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0513307 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0490993 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.047997 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0474487 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0465837 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0455807 |
| COL5A1 | collagen, type V, alpha 1 | -0.04519 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0448508 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0447343 |
| CDH13 | cadherin 13 | -0.0445458 |
| VIM | vimentin | -0.0444059 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0440942 |
| AHR | aryl hydrocarbon receptor | -0.0439183 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0438038 |
| ANXA2 | annexin A2 | -0.0436439 |
| NRP1 | neuropilin 1 | -0.0435574 |
| NRXN3 | neurexin 3 | -0.0432131 |
| RPL35A | ribosomal protein L35a | -0.0428245 |
| RRBP1 | ribosome binding protein 1 | -0.0427826 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0421858 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.041667 |
| CUL3 | cullin 3 | -0.041552 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0415085 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413025 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.040558 |
| USP34 | ubiquitin specific peptidase 34 | -0.0405471 |
| SMAD3 | SMAD family member 3 | -0.0404733 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0404352 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0404239 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0403209 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0402492 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0401998 |
| TAGLN2 | transgelin 2 | -0.0394265 |
| MT1X | metallothionein 1X | -0.0393564 |
| RTN4 | reticulon 4 | -0.0391767 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0391342 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0382959 |
| NKTR | natural killer cell triggering receptor | -0.0381591 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0378813 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0377638 |
| CADM1 | cell adhesion molecule 1 | -0.037674 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0375802 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0373529 |
| AOPEP | aminopeptidase O (putative) | -0.0371268 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.0365297 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0361215 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0360937 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0359016 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0359014 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0358467 |
| EFNA5 | ephrin-A5 | -0.03546 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0353633 |
| MEF2A | myocyte enhancer factor 2A | -0.0352678 |
| ASPH | aspartate beta-hydroxylase | -0.0349354 |
| PMM2 | phosphomannomutase 2 | -0.0346091 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0343279 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0342522 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0341846 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.034102 |
| PALLD | palladin, cytoskeletal associated protein | -0.0340133 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0339845 |
| FAM20C | family with sequence similarity 20, member C | -0.0337329 |
| OSMR | oncostatin M receptor | -0.0335307 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0335148 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0335016 |
| TPM4 | tropomyosin 4 | -0.0333295 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0330872 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0330547 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0329548 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0329001 |
| MAP4 | microtubule-associated protein 4 | -0.0328962 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0328447 |
