| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG9 | sperm associated antigen 9 | 0.0585352 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.05611 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0478388 |
| NUP58 | nucleoporin 58 | 0.0467226 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0465665 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0437192 |
| ECT2 | epithelial cell transforming 2 | 0.04154 |
| HELZ | helicase with zinc finger | 0.0410238 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0399937 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0363011 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0340899 |
| SNX14 | sorting nexin 14 | 0.033828 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0334788 |
| RPLP1 | ribosomal protein, large, P1 | 0.0331401 |
| MORF4L2 | mortality factor 4 like 2 | 0.0324501 |
| PNN | pinin, desmosome associated protein | 0.0324488 |
| GOLGA4 | golgin A4 | 0.0317074 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0304936 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0296926 |
| RBM39 | RNA binding motif protein 39 | 0.0296514 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.029546 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0294963 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0292708 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0289772 |
| SET | SET nuclear proto-oncogene | 0.0286646 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0280317 |
| SRP54 | signal recognition particle 54kDa | 0.0277198 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0275602 |
| COG5 | component of oligomeric golgi complex 5 | 0.0268564 |
| WDR43 | WD repeat domain 43 | 0.0267944 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0267485 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0264559 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0263315 |
| CEP295 | centrosomal protein 295kDa | 0.0263133 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0262461 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0262013 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0261641 |
| SEC24A | SEC24 family member A | 0.0259752 |
| RPL23 | ribosomal protein L23 | 0.0258012 |
| ARF4 | ADP-ribosylation factor 4 | 0.0255782 |
| MKI67 | marker of proliferation Ki-67 | 0.0254951 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0254211 |
| NOP58 | NOP58 ribonucleoprotein | 0.0254117 |
| RACK1 | receptor for activated C kinase 1 | 0.024526 |
| RPL11 | ribosomal protein L11 | 0.024338 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.02423 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.023965 |
| WDR45B | WD repeat domain 45B | 0.0235529 |
| RPL36 | ribosomal protein L36 | 0.0234592 |
| RPS17 | ribosomal protein S17 | 0.0234408 |
| RPL12 | ribosomal protein L12 | 0.0232696 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0231628 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0230247 |
| RPL35 | ribosomal protein L35 | 0.022982 |
| FOXJ3 | forkhead box J3 | 0.0228544 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0228256 |
| SFXN1 | sideroflexin 1 | 0.022818 |
| TFRC | transferrin receptor | 0.0226023 |
| TUBB | tubulin, beta class I | 0.0225457 |
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.0225406 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0223878 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0223698 |
| ATP13A3 | ATPase type 13A3 | 0.0220501 |
| YBX1 | Y box binding protein 1 | 0.0220111 |
| TFG | TRK-fused gene | 0.021913 |
| SIN3A | SIN3 transcription regulator family member A | 0.0218247 |
| KIF20B | kinesin family member 20B | 0.0216125 |
| CEP192 | centrosomal protein 192kDa | 0.0216059 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0214488 |
| AFTPH | aftiphilin | 0.020989 |
| MATR3 | matrin 3 | 0.0209379 |
| CLINT1 | clathrin interactor 1 | 0.0208712 |
| SURF4 | surfeit 4 | 0.0207827 |
| DIAPH3 | diaphanous-related formin 3 | 0.0207668 |
| MED17 | mediator complex subunit 17 | 0.0207262 |
| NONO | non-POU domain containing, octamer-binding | 0.0206351 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0204812 |
| RPS2 | ribosomal protein S2 | 0.0204468 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.020427 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0204151 |
| TEX10 | testis expressed 10 | 0.0203541 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0202578 |
| MRPL3 | mitochondrial ribosomal protein L3 | 0.0201921 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 0.0201762 |
| SSR1 | signal sequence receptor, alpha | 0.020173 |
| XPO1 | exportin 1 | 0.0200424 |
| CCDC88A | coiled-coil domain containing 88A | 0.0199245 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0198528 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | 0.0198516 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.019824 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0198053 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0197321 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0197152 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0194588 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0193858 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0193819 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0193691 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0192236 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0191905 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0191705 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.138844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123931 |
| HMGA2 | high mobility group AT-hook 2 | -0.122374 |
| CD44 | CD44 molecule (Indian blood group) | -0.0992269 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0983707 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0948749 |
| PRKCA | protein kinase C, alpha | -0.0945226 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.094522 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0856951 |
| TMSB10 | thymosin beta 10 | -0.0819263 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.079948 |
| ATXN1 | ataxin 1 | -0.0780122 |
| AHNAK | AHNAK nucleoprotein | -0.0762824 |
| INTS6 | integrator complex subunit 6 | -0.075891 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0754597 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0732446 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0731289 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0705754 |
| ATM | ATM serine/threonine kinase | -0.0674344 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.067087 |
| DST | dystonin | -0.0666025 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0654396 |
| SVIL | supervillin | -0.0643394 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0642807 |
| VIM | vimentin | -0.0636286 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0624802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0611096 |
| RIGI | RNA sensor RIG-I | -0.0599985 |
| LDHA | lactate dehydrogenase A | -0.0599552 |
| VCL | vinculin | -0.0599395 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0591866 |
| ATG7 | autophagy related 7 | -0.0565951 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0563068 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.055508 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0545551 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0544695 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.053341 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0532962 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.052427 |
| GPC6 | glypican 6 | -0.0515431 |
| FMN1 | formin 1 | -0.0504051 |
| EGFR | epidermal growth factor receptor | -0.0498206 |
| PRSS23 | protease, serine, 23 | -0.049087 |
| ASPH | aspartate beta-hydroxylase | -0.0484113 |
| NALCN | sodium leak channel, non selective | -0.0477822 |
| EFNA5 | ephrin-A5 | -0.0476648 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.047471 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0468961 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0467583 |
| SMYD3 | SET and MYND domain containing 3 | -0.0443667 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0442199 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0435279 |
| PCED1B | PC-esterase domain containing 1B | -0.0434663 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0428251 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.042825 |
| RAI14 | retinoic acid induced 14 | -0.0426719 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0426658 |
| PRR16 | proline rich 16 | -0.0424276 |
| RAD51B | RAD51 paralog B | -0.0420012 |
| ANO6 | anoctamin 6 | -0.0419723 |
| FLNB | filamin B, beta | -0.0418068 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0417252 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0415398 |
| FMNL2 | formin-like 2 | -0.0414037 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0403007 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0400942 |
| ZNF609 | zinc finger protein 609 | -0.0399325 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0394137 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0393486 |
| PTK2 | protein tyrosine kinase 2 | -0.0390287 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0388706 |
| ANXA2 | annexin A2 | -0.0387949 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0386937 |
| ETV6 | ets variant 6 | -0.0385207 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0381781 |
| PHF3 | PHD finger protein 3 | -0.0375427 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0371411 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0370756 |
| PCNX4 | pecanex 4 | -0.0369872 |
| HDAC9 | histone deacetylase 9 | -0.0369456 |
| PKM | pyruvate kinase, muscle | -0.0366809 |
| ITGAV | integrin, alpha V | -0.036273 |
| PARD3 | par-3 family cell polarity regulator | -0.0362019 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0357538 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0353634 |
| OSMR | oncostatin M receptor | -0.0353321 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0351814 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0349015 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0341798 |
| CANX | calnexin | -0.0335602 |
| WWOX | WW domain containing oxidoreductase | -0.033423 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0333404 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0332116 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0331396 |
| MYO9A | myosin IXA | -0.0327652 |
| ANGPTL4 | angiopoietin-like 4 | -0.0327152 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0326632 |
| AEBP2 | AE binding protein 2 | -0.0325433 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.032433 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.0324175 |
