| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bestatin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bestatin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0645384 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0514345 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0327132 |
| GPC6 | glypican 6 | 0.0327074 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0308177 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0303787 |
| HMGA2 | high mobility group AT-hook 2 | 0.0281775 |
| WDR26 | WD repeat domain 26 | 0.0267697 |
| FLNB | filamin B, beta | 0.0255054 |
| NDRG1 | N-myc downstream regulated 1 | 0.0254394 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.02291 |
| EFNA5 | ephrin-A5 | 0.0224096 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0222907 |
| SMYD3 | SET and MYND domain containing 3 | 0.0216601 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0216048 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0214863 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0213728 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0212514 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.020995 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0207717 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0205888 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0204852 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0197086 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194986 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0194473 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0185339 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0183068 |
| PRELID2 | PRELI domain containing 2 | 0.018247 |
| NAV2 | neuron navigator 2 | 0.0179318 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0179115 |
| RAD51B | RAD51 paralog B | 0.0177799 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0173778 |
| MEF2D | myocyte enhancer factor 2D | 0.0170401 |
| FAM219A | family with sequence similarity 219, member A | 0.01704 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0169968 |
| ANGPTL4 | angiopoietin-like 4 | 0.0169796 |
| SSH1 | slingshot protein phosphatase 1 | 0.0166834 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0166671 |
| LOXL2 | lysyl oxidase-like 2 | 0.0165806 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0164885 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0164287 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.016334 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0160144 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0160117 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0160043 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0158706 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0158412 |
| SP3 | Sp3 transcription factor | 0.015648 |
| SMOX | spermine oxidase | 0.01555 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0147708 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0144884 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0144219 |
| STC2 | stanniocalcin 2 | 0.0143931 |
| EGFR | epidermal growth factor receptor | 0.0142297 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0142157 |
| PCBP2 | poly(rC) binding protein 2 | 0.0141733 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.014105 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0140885 |
| VEGFC | vascular endothelial growth factor C | 0.0139723 |
| SCFD2 | sec1 family domain containing 2 | 0.013916 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0137712 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0137485 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0136341 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0133045 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0132932 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0132416 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0132227 |
| ATXN1 | ataxin 1 | 0.0130407 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0130289 |
| PLPP3 | phospholipid phosphatase 3 | 0.0129715 |
| PNN | pinin, desmosome associated protein | 0.0128576 |
| NIBAN2 | niban apoptosis regulator 2 | 0.012663 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0126415 |
| BBX | bobby sox homolog (Drosophila) | 0.0125063 |
| PCM1 | pericentriolar material 1 | 0.0123927 |
| CDK19 | cyclin-dependent kinase 19 | 0.0123927 |
| CREBBP | CREB binding protein | 0.0123757 |
| TNS3 | tensin 3 | 0.0122703 |
| SYNJ2 | synaptojanin 2 | 0.0122142 |
| ACTN1 | actinin, alpha 1 | 0.0121722 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0121299 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0121293 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0121137 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0120866 |
| PDGFC | platelet derived growth factor C | 0.0120502 |
| MSN | moesin | 0.0120192 |
| NAV1 | neuron navigator 1 | 0.0119583 |
| METTL15 | methyltransferase like 15 | 0.0117349 |
| PLPP6 | phospholipid phosphatase 6 | 0.0115938 |
| USP34 | ubiquitin specific peptidase 34 | 0.0115647 |
| TGFA | transforming growth factor, alpha | 0.0115396 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0114271 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0113733 |
| VCAN | versican | 0.0113384 |
| FBXO32 | F-box protein 32 | 0.0112973 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0112773 |
| DNMBP | dynamin binding protein | 0.0112308 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0112135 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0111943 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0111915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.395415 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.211446 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.209608 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.195786 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.169185 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.158845 |
| PTMA | prothymosin, alpha | -0.117408 |
| CANX | calnexin | -0.114097 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.113618 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.104289 |
| SQSTM1 | sequestosome 1 | -0.0953003 |
| HLA-B | major histocompatibility complex, class I, B | -0.0832807 |
| VIM | vimentin | -0.0819093 |
| S100A6 | S100 calcium binding protein A6 | -0.0790531 |
| LMNA | lamin A/C | -0.0756514 |
| TMSB4X | thymosin beta 4, X-linked | -0.0727753 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0716698 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0694967 |
| FTL | ferritin, light polypeptide | -0.0691889 |
| FN1 | fibronectin 1 | -0.0655583 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0612901 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0601077 |
| H1-0 | H1.0 linker histone | -0.0567696 |
| B2M | beta-2-microglobulin | -0.0556836 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0549775 |
| RPL35A | ribosomal protein L35a | -0.0545815 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.053936 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0531242 |
| RPL26 | ribosomal protein L26 | -0.0528371 |
| GNAS | GNAS complex locus | -0.0509051 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0508947 |
| RPLP1 | ribosomal protein, large, P1 | -0.0504983 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0499777 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0499116 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.049481 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0482751 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.047863 |
| RPS20 | ribosomal protein S20 | -0.0472598 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0467725 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0464596 |
| RPS24 | ribosomal protein S24 | -0.0436421 |
| ASPH | aspartate beta-hydroxylase | -0.0434539 |
| QKI | QKI, KH domain containing, RNA binding | -0.0429168 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0418328 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0417554 |
| S100A10 | S100 calcium binding protein A10 | -0.0413305 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0411486 |
| IER3 | immediate early response 3 | -0.0409775 |
| MT2A | metallothionein 2A | -0.0404205 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0398895 |
| TMSB10 | thymosin beta 10 | -0.0397718 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0396241 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0392104 |
| TMEM263 | transmembrane protein 263 | -0.039137 |
| RPS21 | ribosomal protein S21 | -0.0390093 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0389794 |
| ANKRD28 | ankyrin repeat domain 28 | -0.038628 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0385774 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0381259 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0376942 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0374102 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0368192 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0362961 |
| EREG | epiregulin | -0.0362599 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0355776 |
| RPS6 | ribosomal protein S6 | -0.0352554 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0349564 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0346183 |
| YBX3 | Y box binding protein 3 | -0.0345539 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0344501 |
| RACK1 | receptor for activated C kinase 1 | -0.0342602 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0334876 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.033435 |
| TXNIP | thioredoxin interacting protein | -0.0332116 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0330598 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.032895 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0327474 |
| RPS27A | ribosomal protein S27a | -0.0323589 |
| DNM1L | dynamin 1-like | -0.0321587 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0320884 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0319127 |
| RBM39 | RNA binding motif protein 39 | -0.0316585 |
| RPLP0 | ribosomal protein, large, P0 | -0.031444 |
| RPS19 | ribosomal protein S19 | -0.0312063 |
| ARF1 | ADP-ribosylation factor 1 | -0.0309518 |
| DENND5B | DENN/MADD domain containing 5B | -0.0309325 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.03085 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0307017 |
| EMP1 | epithelial membrane protein 1 | -0.0305324 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.03025 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0299773 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0299614 |
| COPA | coatomer protein complex, subunit alpha | -0.029852 |
| RPL28 | ribosomal protein L28 | -0.0296766 |
| RLF | rearranged L-myc fusion | -0.029675 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0296549 |
| USP3 | ubiquitin specific peptidase 3 | -0.0294301 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0293555 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0292816 |
| RPL19 | ribosomal protein L19 | -0.0290863 |
