| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0663728 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.066348 |
| FKBP5 | FK506 binding protein 5 | 0.0612203 |
| HOMER2 | homer scaffolding protein 2 | 0.057937 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0473485 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.03906 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0387526 |
| LAMB1 | laminin, beta 1 | 0.0375995 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0289057 |
| MT1X | metallothionein 1X | 0.0281758 |
| SAA2-SAA4 | SAA2-SAA4 readthrough | 0.0266664 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0245785 |
| HPCAL1 | hippocalcin-like 1 | 0.0229432 |
| SSH2 | slingshot protein phosphatase 2 | 0.0222338 |
| HIP1 | huntingtin interacting protein 1 | 0.0221633 |
| POTEF | POTE ankyrin domain family, member F | 0.0210781 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.020892 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0208321 |
| SAA2 | serum amyloid A2 | 0.0207667 |
| NFIA | nuclear factor I/A | 0.019931 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0193817 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0189186 |
| PCBP3 | poly(rC) binding protein 3 | 0.0186891 |
| IL6ST | interleukin 6 signal transducer | 0.0180432 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.016744 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0166512 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0159292 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0156301 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0156043 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0155915 |
| DNM2 | dynamin 2 | 0.0149726 |
| CLMB | calcimembrin | 0.0149257 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0146995 |
| SMIM44 | small integral membrane protein 44 | 0.0146937 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0146713 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0145721 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0143283 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0142484 |
| ZNF608 | zinc finger protein 608 | 0.0141999 |
| NRCAM | neuronal cell adhesion molecule | 0.0141494 |
| CLMP | CXADR-like membrane protein | 0.0137626 |
| AHNAK | AHNAK nucleoprotein | 0.0136576 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0135642 |
| SET | SET nuclear proto-oncogene | 0.0128781 |
| STK39 | serine threonine kinase 39 | 0.0126816 |
| WDR43 | WD repeat domain 43 | 0.0124812 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0124642 |
| PLIN2 | perilipin 2 | 0.0121816 |
| NRP1 | neuropilin 1 | 0.0121506 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0121206 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0117962 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0117854 |
| MYO10 | myosin X | 0.0117597 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0117257 |
| PLS3 | plastin 3 | 0.0115424 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0114451 |
| SVIL | supervillin | 0.011193 |
| POU5F1 | POU class 5 homeobox 1 | 0.0111202 |
| TOP1 | topoisomerase (DNA) I | 0.0110308 |
| STIM1 | stromal interaction molecule 1 | 0.011007 |
| GTF2I | general transcription factor IIi | 0.0109677 |
| UTRN | utrophin | 0.0108305 |
| TMEM178B | transmembrane protein 178B | 0.0108302 |
| PKP4 | plakophilin 4 | 0.010771 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0106286 |
| PDS5A | PDS5 cohesin associated factor A | 0.0106103 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.010452 |
| JPH2 | junctophilin 2 | 0.010218 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0102161 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0101665 |
| TES | testin LIM domain protein | 0.0101302 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0099991 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00998108 |
| FOXO1 | forkhead box O1 | 0.00990031 |
| NCS1 | neuronal calcium sensor 1 | 0.00982485 |
| SLTM | SAFB-like, transcription modulator | 0.00981008 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00978061 |
| HMGB2 | high mobility group box 2 | 0.00966945 |
| ACTN4 | actinin, alpha 4 | 0.00965749 |
| CEP70 | centrosomal protein 70kDa | 0.00963725 |
| MKI67 | marker of proliferation Ki-67 | 0.00958703 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.00958043 |
| EXOC4 | exocyst complex component 4 | 0.00957658 |
| LOC112694756 | uncharaterized LOC112694756 | 0.00957607 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00954995 |
| PXDN | peroxidasin | 0.009517 |
| PLCB4 | phospholipase C, beta 4 | 0.00950334 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 0.00946451 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.00942963 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.00926518 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00926077 |
| ZHX3 | zinc fingers and homeoboxes 3 | 0.00922936 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00910241 |
| GSPT1 | G1 to S phase transition 1 | 0.00907883 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.00896944 |
| XPO1 | exportin 1 | 0.00894715 |
| STIL | SCL/TAL1 interrupting locus | 0.00894487 |
| TUT4 | terminal uridylyl transferase 4 | 0.00893501 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.00890873 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.00884393 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.149846 |
| FRMD4A | FERM domain containing 4A | -0.144511 |
| ASPH | aspartate beta-hydroxylase | -0.0971727 |
| VIM | vimentin | -0.0868014 |
| CD44 | CD44 molecule (Indian blood group) | -0.0822373 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0671158 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.063579 |
| FTL | ferritin, light polypeptide | -0.0611005 |
| NDRG1 | N-myc downstream regulated 1 | -0.0531253 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0518772 |
| RAI14 | retinoic acid induced 14 | -0.0513484 |
| EXT1 | exostosin glycosyltransferase 1 | -0.049902 |
| TMSB10 | thymosin beta 10 | -0.0498685 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0463711 |
| FAT1 | FAT atypical cadherin 1 | -0.0453985 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0439334 |
| CA12 | carbonic anhydrase XII | -0.0426135 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0375568 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.036263 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0359371 |
| LOXL2 | lysyl oxidase-like 2 | -0.0357756 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0350329 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0348907 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0344365 |
| MAP1B | microtubule-associated protein 1B | -0.0341651 |
| B2M | beta-2-microglobulin | -0.0327585 |
| VCL | vinculin | -0.0322273 |
| CADM1 | cell adhesion molecule 1 | -0.0313388 |
| SMAD3 | SMAD family member 3 | -0.0312438 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0307343 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0300598 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.029463 |
| FNDC3B | fibronectin type III domain containing 3B | -0.029414 |
| ETV6 | ets variant 6 | -0.0293972 |
| KYNU | kynureninase | -0.0292817 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0290733 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0280028 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0277214 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.027277 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0267497 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0265501 |
| FAM107B | family with sequence similarity 107, member B | -0.0264319 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0261978 |
| RND3 | Rho family GTPase 3 | -0.0257849 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0257086 |
| HLA-B | major histocompatibility complex, class I, B | -0.0252664 |
| NAV2 | neuron navigator 2 | -0.0251148 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0241706 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0240922 |
| EHBP1 | EH domain binding protein 1 | -0.0240122 |
| CALU | calumenin | -0.0237153 |
| SPAG9 | sperm associated antigen 9 | -0.0232997 |
| PTMA | prothymosin, alpha | -0.0231866 |
| CDCP1 | CUB domain containing protein 1 | -0.0230021 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0229179 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0228741 |
| CANX | calnexin | -0.0225241 |
| CMIP | c-Maf inducing protein | -0.0220408 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0219927 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.02188 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0215898 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.021457 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0213543 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212516 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0208804 |
| TPM1 | tropomyosin 1 (alpha) | -0.0208611 |
| RPL19 | ribosomal protein L19 | -0.0208034 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0203608 |
| RUNX1 | runt-related transcription factor 1 | -0.020135 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0198711 |
| TUSC3 | tumor suppressor candidate 3 | -0.0196164 |
| GLIS3 | GLIS family zinc finger 3 | -0.0196158 |
| GOLGA4 | golgin A4 | -0.019381 |
| RPL35A | ribosomal protein L35a | -0.0193476 |
| RPS19 | ribosomal protein S19 | -0.0192808 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0191217 |
| RPS4X | ribosomal protein S4, X-linked | -0.0190953 |
| ITGAV | integrin, alpha V | -0.0190745 |
| FRMD5 | FERM domain containing 5 | -0.0190174 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0189639 |
| SQSTM1 | sequestosome 1 | -0.0188855 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0188817 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0187736 |
| ATP13A3 | ATPase type 13A3 | -0.0186718 |
| EGFR | epidermal growth factor receptor | -0.0185556 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.018539 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0182072 |
| DGKI | diacylglycerol kinase, iota | -0.0181356 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0180908 |
| COG5 | component of oligomeric golgi complex 5 | -0.0180542 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0180019 |
| PLK2 | polo-like kinase 2 | -0.017864 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0177979 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0177357 |
| HM13 | histocompatibility (minor) 13 | -0.0176887 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0176139 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0174821 |
| NRP2 | neuropilin 2 | -0.017431 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0173754 |
| RPS8 | ribosomal protein S8 | -0.0171751 |
