| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.136548 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.105073 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0776826 |
| MT1X | metallothionein 1X | 0.0744428 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.063323 |
| ANXA1 | annexin A1 | 0.0597961 |
| MCL1 | myeloid cell leukemia 1 | 0.0541695 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0536496 |
| KYNU | kynureninase | 0.0532476 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0524245 |
| MED13L | mediator complex subunit 13-like | 0.0519523 |
| KRT7 | keratin 7, type II | 0.051389 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0504643 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0495524 |
| KRT8 | keratin 8, type II | 0.0490273 |
| POTEF | POTE ankyrin domain family, member F | 0.0477054 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0443307 |
| ACTN4 | actinin, alpha 4 | 0.0431036 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0427708 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0415291 |
| BCL2L1 | BCL2-like 1 | 0.0406717 |
| LAMB1 | laminin, beta 1 | 0.0398393 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0387371 |
| FKBP5 | FK506 binding protein 5 | 0.0380881 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0378179 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0371317 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.035872 |
| VMP1 | vacuole membrane protein 1 | 0.0348947 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0345526 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0325899 |
| JAK1 | Janus kinase 1 | 0.0324607 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0323427 |
| STOM | stomatin | 0.032118 |
| DOCK5 | dedicator of cytokinesis 5 | 0.031172 |
| TGM2 | transglutaminase 2 | 0.0310483 |
| PFKP | phosphofructokinase, platelet | 0.03079 |
| SMYD3 | SET and MYND domain containing 3 | 0.0307253 |
| NRCAM | neuronal cell adhesion molecule | 0.0305345 |
| AHNAK | AHNAK nucleoprotein | 0.0303878 |
| ANGPTL4 | angiopoietin-like 4 | 0.0298049 |
| HPCAL1 | hippocalcin-like 1 | 0.0290348 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0287637 |
| GLIS3 | GLIS family zinc finger 3 | 0.0285853 |
| RAB10 | RAB10, member RAS oncogene family | 0.0283107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.028027 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0277921 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.027642 |
| FOXP1 | forkhead box P1 | 0.0275014 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0274007 |
| OSMR | oncostatin M receptor | 0.0260482 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0259685 |
| ATF6 | activating transcription factor 6 | 0.0257448 |
| ITSN2 | intersectin 2 | 0.0255956 |
| IL6ST | interleukin 6 signal transducer | 0.0253617 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0253383 |
| BICC1 | BicC family RNA binding protein 1 | 0.0253032 |
| KRT81 | keratin 81, type II | 0.0251727 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0250934 |
| ABHD2 | abhydrolase domain containing 2 | 0.0250161 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0249922 |
| NFIA | nuclear factor I/A | 0.0249498 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.024626 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0246207 |
| EXT1 | exostosin glycosyltransferase 1 | 0.024346 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0241861 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0237782 |
| ASPH | aspartate beta-hydroxylase | 0.0233364 |
| XPO1 | exportin 1 | 0.0231842 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0231681 |
| TMEM245 | transmembrane protein 245 | 0.0231645 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0230837 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.023035 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0227199 |
| RBM39 | RNA binding motif protein 39 | 0.0226715 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0222826 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0222636 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0222431 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0222376 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0219766 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0219744 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0217446 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0216666 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0215077 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.021368 |
| LDHA | lactate dehydrogenase A | 0.0213382 |
| ITGAV | integrin, alpha V | 0.0212213 |
| KRT18 | keratin 18, type I | 0.0212071 |
| WWOX | WW domain containing oxidoreductase | 0.0211142 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0210658 |
| GPC6 | glypican 6 | 0.0209551 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0208469 |
| VCL | vinculin | 0.0205054 |
| GPHN | gephyrin | 0.020094 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0200405 |
| EGR1 | early growth response 1 | 0.0196781 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0196759 |
| KLHL5 | kelch-like family member 5 | 0.0195228 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0194283 |
| SGMS1 | sphingomyelin synthase 1 | 0.0192408 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0189455 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.187003 |
| FTL | ferritin, light polypeptide | -0.126502 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0969208 |
| PTMA | prothymosin, alpha | -0.0888318 |
| MT2A | metallothionein 2A | -0.0803645 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0781807 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0779055 |
| USP3 | ubiquitin specific peptidase 3 | -0.0712101 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0679488 |
| NDRG1 | N-myc downstream regulated 1 | -0.0603907 |
| VIM | vimentin | -0.0589334 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0566075 |
| SPAG9 | sperm associated antigen 9 | -0.0564979 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0536854 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0524052 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0489603 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.048948 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0467665 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0465102 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0458661 |
| ENO1 | enolase 1, (alpha) | -0.042625 |
| RPS19 | ribosomal protein S19 | -0.0423451 |
| MKI67 | marker of proliferation Ki-67 | -0.0416053 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.040323 |
| PGK1 | phosphoglycerate kinase 1 | -0.0392272 |
| FAM107B | family with sequence similarity 107, member B | -0.0384841 |
| HELZ | helicase with zinc finger | -0.0358341 |
| GOLGA4 | golgin A4 | -0.0350678 |
| ECT2 | epithelial cell transforming 2 | -0.0338826 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0336643 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0336212 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0327194 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0326418 |
| FAM13A | family with sequence similarity 13, member A | -0.0325212 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0324148 |
| CANX | calnexin | -0.031382 |
| RPL37A | ribosomal protein L37a | -0.0308418 |
| TKT | transketolase | -0.0308123 |
| PARD3 | par-3 family cell polarity regulator | -0.0307811 |
| PDE10A | phosphodiesterase 10A | -0.0291669 |
| RPL18 | ribosomal protein L18 | -0.0281761 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0273876 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0271809 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0269422 |
| PFN1 | profilin 1 | -0.0266847 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0264025 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0260905 |
| RPL26 | ribosomal protein L26 | -0.0260826 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0255504 |
| QKI | QKI, KH domain containing, RNA binding | -0.0255034 |
| FBL | fibrillarin | -0.0254469 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.024939 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0242785 |
| CD44 | CD44 molecule (Indian blood group) | -0.0241641 |
| RAI14 | retinoic acid induced 14 | -0.0240913 |
| RIN2 | Ras and Rab interactor 2 | -0.023863 |
| HMGA1 | high mobility group AT-hook 1 | -0.0235981 |
| STC1 | stanniocalcin 1 | -0.0232188 |
| SETD5 | SET domain containing 5 | -0.0231746 |
| FMNL2 | formin-like 2 | -0.0229293 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0226495 |
| RASA2 | RAS p21 protein activator 2 | -0.022641 |
| RPS27 | ribosomal protein S27 | -0.0225748 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0224207 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0223294 |
| H1-0 | H1.0 linker histone | -0.0222713 |
| RPL31 | ribosomal protein L31 | -0.0222642 |
| RAI1 | retinoic acid induced 1 | -0.0222402 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0222108 |
| DENND1A | DENN/MADD domain containing 1A | -0.0221259 |
| RPS8 | ribosomal protein S8 | -0.0219379 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0218398 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.021836 |
| MORF4L2 | mortality factor 4 like 2 | -0.0215395 |
| FLNB | filamin B, beta | -0.021079 |
| S100A6 | S100 calcium binding protein A6 | -0.0209412 |
| NGLY1 | N-glycanase 1 | -0.0208499 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0205114 |
| RPS14 | ribosomal protein S14 | -0.0204006 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0203875 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0203796 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0202163 |
| WDR45B | WD repeat domain 45B | -0.0201709 |
| EGFR | epidermal growth factor receptor | -0.0201128 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0200631 |
| CDC27 | cell division cycle 27 | -0.0199243 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0198911 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0198602 |
| RPS3 | ribosomal protein S3 | -0.0197319 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0197079 |
| RPL35A | ribosomal protein L35a | -0.0196272 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0194711 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0194581 |
| MYO10 | myosin X | -0.0194312 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0194087 |
| ATP13A3 | ATPase type 13A3 | -0.0193593 |
| LAMB3 | laminin, beta 3 | -0.0192811 |
| RNF24 | ring finger protein 24 | -0.0191943 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0191449 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0189449 |
