Betamethasone dipropionate_AN3 CA Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Betamethasone dipropionate perturbation in AN3 CA cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Betamethasone dipropionate_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MEST mesoderm specific transcript 0.240022
PDE4D phosphodiesterase 4D, cAMP-specific 0.0636847
VEGFA vascular endothelial growth factor A 0.0532899
MEOX2 mesenchyme homeobox 2 0.0455901
ZNF292 zinc finger protein 292 0.0348741
RPL3 ribosomal protein L3 0.0344108
GSE1 Gse1 coiled-coil protein 0.0339042
ARHGAP21 Rho GTPase activating protein 21 0.032461
EEF2 eukaryotic translation elongation factor 2 0.032348
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0307717
KIF11 kinesin family member 11 0.0281067
OLA1 Obg-like ATPase 1 0.0272317
BIRC6 baculoviral IAP repeat containing 6 0.0266698
PRELID2 PRELI domain containing 2 0.0262439
CCNL1 cyclin L1 0.026196
ZBTB20 zinc finger and BTB domain containing 20 0.0258278
PDE4B phosphodiesterase 4B, cAMP-specific 0.0241521
PBX3 pre-B-cell leukemia homeobox 3 0.0232259
CSNK1A1 casein kinase 1, alpha 1 0.0232146
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0231531
HOXA3 homeobox A3 0.0229481
RAD51B RAD51 paralog B 0.0228379
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0217776
BOC BOC cell adhesion associated, oncogene regulated 0.0216586
COL4A5 collagen, type IV, alpha 5 0.0215818
NFIA nuclear factor I/A 0.0215813
ZNF608 zinc finger protein 608 0.0215707
PDGFC platelet derived growth factor C 0.0215478
PTEN phosphatase and tensin homolog 0.0215331
SRRM2 serine/arginine repetitive matrix 2 0.0213609
PNN pinin, desmosome associated protein 0.0213204
BCAS3 breast carcinoma amplified sequence 3 0.021262
FTH1 ferritin, heavy polypeptide 1 0.0211858
GTF2I general transcription factor IIi 0.0207742
GPC6 glypican 6 0.0207105
ETNK1 ethanolamine kinase 1 0.0206451
PDE10A phosphodiesterase 10A 0.0201847
PCBP2 poly(rC) binding protein 2 0.0196457
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.0195809
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0195791
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0195227
PDS5A PDS5 cohesin associated factor A 0.0194784
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.0194638
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0194129
TTBK2 tau tubulin kinase 2 0.0193281
RNF145 ring finger protein 145 0.0192102
DBN1 drebrin 1 0.0189939
NUDCD3 NudC domain containing 3 0.0185071
SH3PXD2A SH3 and PX domains 2A 0.0183456
SFPQ splicing factor proline/glutamine-rich 0.0182935
FGFR2 fibroblast growth factor receptor 2 0.0180762
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0180629
ARID1A AT rich interactive domain 1A (SWI-like) 0.0180351
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.0180086
RPS18 ribosomal protein S18 0.0179815
TOP1 topoisomerase (DNA) I 0.017946
PRRC2C proline-rich coiled-coil 2C 0.0179274
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.0178659
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0177547
GAPVD1 GTPase activating protein and VPS9 domains 1 0.0171808
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0171756
FAM219A family with sequence similarity 219, member A 0.0169623
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0168889
RABGAP1 RAB GTPase activating protein 1 0.0168861
PRKG1 protein kinase, cGMP-dependent, type I 0.0168368
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0168232
SRP54 signal recognition particle 54kDa 0.0167371
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0166572
SMC1A structural maintenance of chromosomes 1A 0.0165961
HEATR1 HEAT repeat containing 1 0.0165808
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0165349
TBK1 TANK-binding kinase 1 0.0164431
CABIN1 calcineurin binding protein 1 0.0163398
KDM1A lysine (K)-specific demethylase 1A 0.0160934
IGF2 insulin-like growth factor 2 0.0160186
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.0159925
NDFIP1 Nedd4 family interacting protein 1 0.0158516
CKAP5 cytoskeleton associated protein 5 0.0158492
TNRC6A trinucleotide repeat containing 6A 0.0158218
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0157775
N4BP1 NEDD4 binding protein 1 0.0156963
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.015646
SF1 splicing factor 1 0.0155977
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0155721
CEP192 centrosomal protein 192kDa 0.0155652
HYOU1 hypoxia up-regulated 1 0.0155571
MYH9 myosin, heavy chain 9, non-muscle 0.0155021
NCAPG2 non-SMC condensin II complex, subunit G2 0.0154733
PPA2 pyrophosphatase (inorganic) 2 0.0154622
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0153972
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.015371
PELI1 pellino E3 ubiquitin protein ligase 1 0.0153602
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.0153496
ZMYM2 zinc finger, MYM-type 2 0.015332
MACF1 microtubule-actin crosslinking factor 1 0.0153185
ATXN2L ataxin 2-like 0.0152157
DIAPH3 diaphanous-related formin 3 0.0150504
NLN neurolysin (metallopeptidase M3 family) 0.0150161
MLEC malectin 0.0149298
KDM6A lysine (K)-specific demethylase 6A 0.0148797

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.257725
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.212921
PTMA prothymosin, alpha -0.10803
SOX4 SRY (sex determining region Y)-box 4 -0.0880933
RPLP1 ribosomal protein, large, P1 -0.081636
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0794172
IER3 immediate early response 3 -0.0765814
RPS6 ribosomal protein S6 -0.0757158
MGP matrix Gla protein -0.0742137
PEG10 paternally expressed 10 -0.0710013
TMSB10 thymosin beta 10 -0.0709896
ACTG1 actin gamma 1 -0.0693471
RPS8 ribosomal protein S8 -0.068728
RPL34 ribosomal protein L34 -0.0684484
RPS24 ribosomal protein S24 -0.0675713
CADM2 cell adhesion molecule 2 -0.06206
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0619936
TPT1 tumor protein, translationally-controlled 1 -0.0593814
TMSB4X thymosin beta 4, X-linked -0.0569386
RPL35A ribosomal protein L35a -0.0560778
RPLP2 ribosomal protein, large, P2 -0.0544312
RPS23 ribosomal protein S23 -0.0535933
FTL ferritin, light polypeptide -0.0515284
RACK1 receptor for activated C kinase 1 -0.050767
RPS13 ribosomal protein S13 -0.0476796
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0476305
RPS19 ribosomal protein S19 -0.0472027
CANX calnexin -0.0470339
RPS27A ribosomal protein S27a -0.0463193
FGFR1 fibroblast growth factor receptor 1 -0.0462237
RPS11 ribosomal protein S11 -0.0460305
RPL12 ribosomal protein L12 -0.0454499
RPL31 ribosomal protein L31 -0.0442976
RPL37 ribosomal protein L37 -0.0406962
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0404476
RPS5 ribosomal protein S5 -0.0400899
RPS25 ribosomal protein S25 -0.0390654
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0386545
RPLP0 ribosomal protein, large, P0 -0.0384951
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0377005
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0368071
RAB7A RAB7A, member RAS oncogene family -0.0363894
HMGB1 high mobility group box 1 -0.0362212
TRIO trio Rho guanine nucleotide exchange factor -0.0353907
RPL8 ribosomal protein L8 -0.0344278
WSB1 WD repeat and SOCS box containing 1 -0.0343213
RPL19 ribosomal protein L19 -0.0340922
SLC38A2 solute carrier family 38, member 2 -0.0337554
MYOF myoferlin -0.0333681
TPI1 triosephosphate isomerase 1 -0.0332283
RPS15 ribosomal protein S15 -0.0331586
RSL1D1 ribosomal L1 domain containing 1 -0.032779
RPL32 ribosomal protein L32 -0.0319489
RPL5 ribosomal protein L5 -0.0319114
RPL7A ribosomal protein L7a -0.03185
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.031728
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0315612
KDM5B lysine (K)-specific demethylase 5B -0.0314244
CSDE1 cold shock domain containing E1, RNA-binding -0.0312748
RPL23 ribosomal protein L23 -0.031208
RPL11 ribosomal protein L11 -0.0302724
RPL10A ribosomal protein L10a -0.0301312
FBXO11 F-box protein 11 -0.0299967
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0298828
RPL38 ribosomal protein L38 -0.0293935
RPS17 ribosomal protein S17 -0.0292944
RPL7 ribosomal protein L7 -0.0291929
RPS12 ribosomal protein S12 -0.0290422
CCNI cyclin I -0.0289775
SEPTIN11 septin 11 -0.0280325
S100A9 S100 calcium binding protein A9 -0.0276085
PGK1 phosphoglycerate kinase 1 -0.0273318
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0270323
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.0265585
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0265268
ENO1 enolase 1, (alpha) -0.0264676
SFTPA2 surfactant protein A2 -0.0263037
RPS3 ribosomal protein S3 -0.0261507
JMJD1C jumonji domain containing 1C -0.0261145
RPL30 ribosomal protein L30 -0.0260842
RPS21 ribosomal protein S21 -0.0258891
ARID4B AT rich interactive domain 4B (RBP1-like) -0.025857
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0255736
RLF rearranged L-myc fusion -0.0255032
RPS10 ribosomal protein S10 -0.0253731
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0248581
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0247867
RPL4 ribosomal protein L4 -0.0243037
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0242854
RPL18 ribosomal protein L18 -0.0239963
RPL28 ribosomal protein L28 -0.0238853
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.023832
RPL26 ribosomal protein L26 -0.0237632
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.0234943
BCOR BCL6 corepressor -0.0232888
FNDC3B fibronectin type III domain containing 3B -0.0232686
EIF1 eukaryotic translation initiation factor 1 -0.0231105
RPS14 ribosomal protein S14 -0.0229521
UBC ubiquitin C -0.0228599
RAB1A RAB1A, member RAS oncogene family -0.0227793