| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.210385 |
| POTEF | POTE ankyrin domain family, member F | 0.112594 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0725037 |
| TOP1 | topoisomerase (DNA) I | 0.0722085 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0638659 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.060679 |
| FKBP5 | FK506 binding protein 5 | 0.0547512 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0541887 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0491203 |
| TXNIP | thioredoxin interacting protein | 0.0446172 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0414458 |
| RTN4 | reticulon 4 | 0.038347 |
| HMGA2 | high mobility group AT-hook 2 | 0.0370096 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0367727 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0355772 |
| AHNAK | AHNAK nucleoprotein | 0.0347024 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0298815 |
| CAPRIN2 | caprin family member 2 | 0.0291208 |
| PON2 | paraoxonase 2 | 0.0283682 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0276149 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0245417 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0227601 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0221839 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0218721 |
| PLEC | plectin | 0.0207636 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0207099 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0204013 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0190759 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0190668 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0181532 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0181429 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0180882 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0176426 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0172892 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0171392 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.0161487 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0160395 |
| TJP1 | tight junction protein 1 | 0.0159794 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0159091 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.015788 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0157758 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.015581 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0154389 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0151341 |
| BCL2L1 | BCL2-like 1 | 0.0150184 |
| YAP1 | Yes-associated protein 1 | 0.0148148 |
| MUC17 | mucin 17, cell surface associated | 0.0147444 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0145386 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0142496 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0142239 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0140436 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0138472 |
| ITGB4 | integrin, beta 4 | 0.0138171 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0137106 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0136851 |
| FOSL1 | FOS-like antigen 1 | 0.0135882 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0135738 |
| PTEN | phosphatase and tensin homolog | 0.0126021 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0125952 |
| TJP2 | tight junction protein 2 | 0.0125447 |
| RNASET2 | ribonuclease T2 | 0.012211 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0122095 |
| KIAA0232 | KIAA0232 | 0.0121999 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0121983 |
| CCNL1 | cyclin L1 | 0.0120698 |
| EPAS1 | endothelial PAS domain protein 1 | 0.011868 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0118468 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.011738 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0114921 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0114166 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0113847 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0113216 |
| RREB1 | ras responsive element binding protein 1 | 0.0112604 |
| FMNL2 | formin-like 2 | 0.0111102 |
| MT1X | metallothionein 1X | 0.0110431 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0110104 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0109887 |
| NONO | non-POU domain containing, octamer-binding | 0.010949 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0109092 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0108985 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0107802 |
| EREG | epiregulin | 0.0106394 |
| TGM2 | transglutaminase 2 | 0.0106102 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0105956 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0105782 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0102398 |
| TMEM164 | transmembrane protein 164 | 0.0101653 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0101241 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0100399 |
| PLS3 | plastin 3 | 0.0100195 |
| TNS4 | tensin 4 | 0.00965862 |
| TPM4 | tropomyosin 4 | 0.00962266 |
| CYRIB | CYFIP related Rac1 interactor B | 0.00958947 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00957136 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00956033 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 | 0.00949183 |
| MATR3 | matrin 3 | 0.00938763 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00937188 |
| IL6ST | interleukin 6 signal transducer | 0.00935797 |
| THOC2 | THO complex 2 | 0.00923984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.15362 |
| LAMB3 | laminin, beta 3 | -0.0910295 |
| TMSB10 | thymosin beta 10 | -0.0900152 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0824668 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0762553 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0703349 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0686886 |
| TXNRD1 | thioredoxin reductase 1 | -0.0593378 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0583344 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0520234 |
| PTMA | prothymosin, alpha | -0.0502879 |
| LMO7 | LIM domain 7 | -0.0473069 |
| S100A10 | S100 calcium binding protein A10 | -0.0434165 |
| FAM107B | family with sequence similarity 107, member B | -0.04243 |
| ASPH | aspartate beta-hydroxylase | -0.0413064 |
| B2M | beta-2-microglobulin | -0.0396401 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0390337 |
| UBC | ubiquitin C | -0.0365958 |
| VCAN | versican | -0.0364764 |
| VIM | vimentin | -0.0364397 |
| DSG2 | desmoglein 2 | -0.0362543 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0356489 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.035053 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0345017 |
| NDRG1 | N-myc downstream regulated 1 | -0.0343237 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0342747 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0337923 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0335441 |
| SMAD3 | SMAD family member 3 | -0.0328473 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0328083 |
| STK39 | serine threonine kinase 39 | -0.0321166 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0320643 |
| MXD1 | MAX dimerization protein 1 | -0.0320581 |
| RPL37A | ribosomal protein L37a | -0.0317285 |
| LAMC2 | laminin, gamma 2 | -0.031539 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0313463 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.031342 |
| RPL12 | ribosomal protein L12 | -0.0309577 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0304942 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0300468 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0298669 |
| RIOK3 | RIO kinase 3 | -0.0297337 |
| EZR | ezrin | -0.0295035 |
| EGFR | epidermal growth factor receptor | -0.0292992 |
| ANXA2 | annexin A2 | -0.0290139 |
| RPS27A | ribosomal protein S27a | -0.0288862 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0286528 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0281858 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0281724 |
| RPLP1 | ribosomal protein, large, P1 | -0.0277881 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0277017 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0274525 |
| FTL | ferritin, light polypeptide | -0.026928 |
| RPS3 | ribosomal protein S3 | -0.0267031 |
| JMJD1C | jumonji domain containing 1C | -0.0265933 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0264901 |
| RPS8 | ribosomal protein S8 | -0.0261482 |
| RPL35A | ribosomal protein L35a | -0.025602 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0254125 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0250094 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0243831 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0240908 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0238288 |
| RPL8 | ribosomal protein L8 | -0.023803 |
| RPS24 | ribosomal protein S24 | -0.0236179 |
| PARD3 | par-3 family cell polarity regulator | -0.0234925 |
| ACTG1 | actin gamma 1 | -0.0234864 |
| HMGA1 | high mobility group AT-hook 1 | -0.0233759 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.023341 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0230018 |
| PGK1 | phosphoglycerate kinase 1 | -0.0228332 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0228112 |
| SQSTM1 | sequestosome 1 | -0.0228012 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.022461 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0222139 |
| RPLP0 | ribosomal protein, large, P0 | -0.0220939 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0215382 |
| RPL34 | ribosomal protein L34 | -0.0213312 |
| KLK10 | kallikrein-related peptidase 10 | -0.0209891 |
| RPLP2 | ribosomal protein, large, P2 | -0.0209405 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0209157 |
| S100A11 | S100 calcium binding protein A11 | -0.0207207 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0206362 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0203747 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0203539 |
| FLNB | filamin B, beta | -0.0200077 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.019979 |
| ENO1 | enolase 1, (alpha) | -0.0199735 |
| RPS13 | ribosomal protein S13 | -0.0198714 |
| GOLGA4 | golgin A4 | -0.0198336 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0195725 |
| SVIL | supervillin | -0.0193981 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0193736 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0192322 |
| LDHA | lactate dehydrogenase A | -0.0189932 |
| DIAPH2 | diaphanous-related formin 2 | -0.0187106 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.018702 |
| RPL31 | ribosomal protein L31 | -0.0184855 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0184354 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0182151 |
