| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.025139 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.02503 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0215631 |
| RUNX1 | runt-related transcription factor 1 | 0.0199946 |
| INTS6 | integrator complex subunit 6 | 0.0186149 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0177747 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0169076 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0168542 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0165064 |
| CCNL1 | cyclin L1 | 0.0158714 |
| MCL1 | myeloid cell leukemia 1 | 0.0137303 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0134773 |
| VEGFA | vascular endothelial growth factor A | 0.0133442 |
| SHROOM3 | shroom family member 3 | 0.0131459 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0129543 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0126627 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0123856 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.012264 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0122037 |
| FAM168A | family with sequence similarity 168, member A | 0.0121795 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0120771 |
| PLSCR2 | phospholipid scramblase 2 | 0.0120218 |
| MT2A | metallothionein 2A | 0.0116202 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0115022 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0114457 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.011229 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0111981 |
| WWC1 | WW and C2 domain containing 1 | 0.0108237 |
| SLC22A23 | solute carrier family 22, member 23 | 0.01069 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0105655 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0103451 |
| VMP1 | vacuole membrane protein 1 | 0.0102382 |
| RBM33 | RNA binding motif protein 33 | 0.00997902 |
| RPL37A | ribosomal protein L37a | 0.009958 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00983794 |
| PRELID2 | PRELI domain containing 2 | 0.00971234 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0096565 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00957611 |
| ZNF292 | zinc finger protein 292 | 0.00951002 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00945535 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.00940812 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00935762 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.00931626 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00916911 |
| TUFT1 | tuftelin 1 | 0.00914706 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00907029 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00894018 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0088475 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00884373 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00878874 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00876348 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00873626 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00863372 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00854677 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00851947 |
| EHF | ets homologous factor | 0.00839799 |
| BATF | basic leucine zipper transcription factor, ATF-like | 0.0082711 |
| RPL3 | ribosomal protein L3 | 0.0081378 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00791775 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00791759 |
| CTBP2 | C-terminal binding protein 2 | 0.00791454 |
| KRT86 | keratin 86, type II | 0.0078384 |
| NPTN | neuroplastin | 0.00779967 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00760953 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.0076049 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.00754991 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00753793 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.00753529 |
| AZIN1 | antizyme inhibitor 1 | 0.00751254 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.00746887 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00745565 |
| RBM4 | RNA binding motif protein 4 | 0.00744517 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.00744162 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00743096 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00731663 |
| DTNA | dystrobrevin, alpha | 0.00728545 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00720969 |
| DENND5A | DENN/MADD domain containing 5A | 0.00719006 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.00718502 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.00718393 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00717244 |
| YAP1 | Yes-associated protein 1 | 0.00713413 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00708863 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00708328 |
| FAM219A | family with sequence similarity 219, member A | 0.00705806 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00701487 |
| SCFD1 | sec1 family domain containing 1 | 0.00699818 |
| CCNY | cyclin Y | 0.00695584 |
| HELZ | helicase with zinc finger | 0.00694424 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0069197 |
| IRS2 | insulin receptor substrate 2 | 0.00689033 |
| FNBP1L | formin binding protein 1-like | 0.00688536 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0068729 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00687222 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00683899 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00663878 |
| VCL | vinculin | 0.00663292 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0066076 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00656866 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.00652699 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | -0.141639 |
| RPL23 | ribosomal protein L23 | -0.113415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0892354 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0818336 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0811279 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0756827 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0709533 |
| ASPH | aspartate beta-hydroxylase | -0.0640725 |
| CDK12 | cyclin-dependent kinase 12 | -0.0535656 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.053165 |
| ACTG1 | actin gamma 1 | -0.0514343 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484755 |
| PTMA | prothymosin, alpha | -0.0483038 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0447225 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0424516 |
| TMSB4X | thymosin beta 4, X-linked | -0.0421232 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0420837 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0407737 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0395364 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0394279 |
| SLC38A1 | solute carrier family 38, member 1 | -0.037373 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0362883 |
| LASP1 | LIM and SH3 protein 1 | -0.0333257 |
| RPL35A | ribosomal protein L35a | -0.0329843 |
| TMSB10 | thymosin beta 10 | -0.0317591 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0317286 |
| CCND1 | cyclin D1 | -0.0314033 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0304705 |
| PGK1 | phosphoglycerate kinase 1 | -0.0302782 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0297482 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293466 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0288923 |
| B2M | beta-2-microglobulin | -0.0278341 |
| RPL12 | ribosomal protein L12 | -0.0270022 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0266547 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0263827 |
| OSMR | oncostatin M receptor | -0.0261373 |
| NCOA6 | nuclear receptor coactivator 6 | -0.026128 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0261185 |
| DUSP4 | dual specificity phosphatase 4 | -0.025618 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0253346 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0248315 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0247861 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0245607 |
| CCNI | cyclin I | -0.0242079 |
| CLTC | clathrin, heavy chain (Hc) | -0.0239808 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0238241 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0230598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0229594 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0221588 |
| RPS8 | ribosomal protein S8 | -0.0220744 |
| RPL8 | ribosomal protein L8 | -0.0220074 |
| TMEM123 | transmembrane protein 123 | -0.0219544 |
| KRT19 | keratin 19, type I | -0.0219089 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0217003 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.021698 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0216577 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0215812 |
| PFDN4 | prefoldin subunit 4 | -0.0214474 |
| S100A9 | S100 calcium binding protein A9 | -0.0213718 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.021 |
| HLA-B | major histocompatibility complex, class I, B | -0.020751 |
| UBC | ubiquitin C | -0.0207315 |
| PRR11 | proline rich 11 | -0.0206976 |
| DSTN | destrin (actin depolymerizing factor) | -0.0206686 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0205165 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0204988 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0203482 |
| RESF1 | retroelement silencing factor 1 | -0.0202871 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0202413 |
| SMYD3 | SET and MYND domain containing 3 | -0.0201923 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0199058 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.019883 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0198218 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0196999 |
| CD164 | CD164 molecule, sialomucin | -0.0194468 |
| HLA-C | major histocompatibility complex, class I, C | -0.0192756 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0192278 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0189807 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0189638 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0188958 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0188763 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0188013 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0186833 |
| NTN4 | netrin 4 | -0.0185934 |
| MYO1D | myosin ID | -0.0184195 |
| GNAS | GNAS complex locus | -0.0183085 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0182931 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0181085 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0178323 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.017826 |
| LDHA | lactate dehydrogenase A | -0.0177835 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.017752 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0177114 |
| S100A6 | S100 calcium binding protein A6 | -0.0173732 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0172234 |
| LMNA | lamin A/C | -0.0171182 |
| RPL34 | ribosomal protein L34 | -0.0169993 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0169108 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0168486 |
