Betamethasone dipropionate_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Betamethasone dipropionate perturbation in CHP-212 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Betamethasone dipropionate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NRG1 neuregulin 1 0.188918
AKAP12 A kinase (PRKA) anchor protein 12 0.170087
VCL vinculin 0.106001
NALF1 NALCN channel auxiliary factor 1 0.0737472
DPH6 diphthamine biosynthesis 6 0.063207
EXT1 exostosin glycosyltransferase 1 0.0619111
LSAMP limbic system-associated membrane protein 0.0521805
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.0509071
PLAT plasminogen activator, tissue 0.0495948
GPC5 glypican 5 0.0441237
PTPRM protein tyrosine phosphatase, receptor type, M 0.0426717
LPIN1 lipin 1 0.040249
ANTXR1 anthrax toxin receptor 1 0.0401958
PRKCA protein kinase C, alpha 0.0399665
MSI2 musashi RNA-binding protein 2 0.0396678
THSD4 thrombospondin, type I, domain containing 4 0.0395727
MYH9 myosin, heavy chain 9, non-muscle 0.0391758
TRIO trio Rho guanine nucleotide exchange factor 0.0379688
VMP1 vacuole membrane protein 1 0.0363084
LINGO2 leucine rich repeat and Ig domain containing 2 0.0357254
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0347286
MACF1 microtubule-actin crosslinking factor 1 0.0342517
TOP1 topoisomerase (DNA) I 0.0334949
FMN1 formin 1 0.0322003
CEMIP cell migration inducing protein, hyaluronan binding 0.0307415
IGF2 insulin-like growth factor 2 0.0301453
HMGA2 high mobility group AT-hook 2 0.0300788
NPAS2 neuronal PAS domain protein 2 0.0297942
ZSWIM6 zinc finger, SWIM-type containing 6 0.0292881
RPTOR regulatory associated protein of MTOR, complex 1 0.0290132
MAML2 mastermind-like 2 (Drosophila) 0.0282922
MCL1 myeloid cell leukemia 1 0.0277832
BICD1 bicaudal D homolog 1 (Drosophila) 0.0266895
CDH13 cadherin 13 0.0266644
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0264512
FNDC3A fibronectin type III domain containing 3A 0.0261818
FRMD4A FERM domain containing 4A 0.0259154
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0257829
CADM1 cell adhesion molecule 1 0.0257405
NCOR2 nuclear receptor corepressor 2 0.0249691
AHR aryl hydrocarbon receptor 0.0247488
LPP LIM domain containing preferred translocation partner in lipoma 0.0247275
UNC5C unc-5 homolog C (C. elegans) 0.0243472
TLE4 transducin-like enhancer of split 4 0.0242604
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.0233742
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0232765
PRKCE protein kinase C, epsilon 0.023186
MAPK10 mitogen-activated protein kinase 10 0.0231387
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0231158
SEPTIN9 septin 9 0.022727
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.0225576
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0224273
PTPRE protein tyrosine phosphatase, receptor type, E 0.0222802
ZCCHC7 zinc finger, CCHC domain containing 7 0.0221849
SDK1 sidekick cell adhesion molecule 1 0.0220026
UBAP2L ubiquitin associated protein 2-like 0.0218534
EXOC4 exocyst complex component 4 0.0218137
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0212929
THBS1 thrombospondin 1 0.0211123
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0210717
TPM1 tropomyosin 1 (alpha) 0.0210322
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0205303
ARHGAP9 Rho GTPase activating protein 9 0.0203694
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.0203103
KAT6A K(lysine) acetyltransferase 6A 0.0203015
RBM33 RNA binding motif protein 33 0.0201493
DNM3 dynamin 3 0.0196973
BCAS3 breast carcinoma amplified sequence 3 0.0196256
IARS1 isoleucyl-tRNA synthetase 1 0.0194597
EFNA5 ephrin-A5 0.0193595
ADARB1 adenosine deaminase, RNA-specific, B1 0.0193128
FKBP5 FK506 binding protein 5 0.0192879
AUTS2 autism susceptibility candidate 2 0.0191277
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.0189404
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0189361
PDLIM5 PDZ and LIM domain 5 0.0188684
MYO1E myosin IE 0.0187287
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.0187153
MBNL1 muscleblind-like splicing regulator 1 0.0186618
MED13L mediator complex subunit 13-like 0.0185451
AK1 adenylate kinase 1 0.0184949
STK38L serine/threonine kinase 38 like 0.0184911
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.0184869
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0184707
RPL3 ribosomal protein L3 0.0184082
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0183834
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0183129
RBM26 RNA binding motif protein 26 0.0182256
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.017977
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0178488
POTEF POTE ankyrin domain family, member F 0.0177189
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0176363
TRPS1 trichorhinophalangeal syndrome I 0.0176126
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0173464
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0172872
PCBP3 poly(rC) binding protein 3 0.0172115
SRRM2 serine/arginine repetitive matrix 2 0.0172069
ATXN10 ataxin 10 0.0171676
EGFR epidermal growth factor receptor 0.0171089
FLT1 fms-related tyrosine kinase 1 0.0171032

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.229883
VIM vimentin -0.07287
COL1A1 collagen, type I, alpha 1 -0.0630136
PTMA prothymosin, alpha -0.0609247
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0556424
RPLP1 ribosomal protein, large, P1 -0.0530618
RPL35A ribosomal protein L35a -0.0528978
RPS24 ribosomal protein S24 -0.0491135
RPS6 ribosomal protein S6 -0.0467524
RPL34 ribosomal protein L34 -0.0462622
COL3A1 collagen, type III, alpha 1 -0.0459314
HAND2 heart and neural crest derivatives expressed 2 -0.0452019
RPL19 ribosomal protein L19 -0.0451617
EIF1 eukaryotic translation initiation factor 1 -0.0447366
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.044495
TPT1 tumor protein, translationally-controlled 1 -0.0431602
FNBP1 formin binding protein 1 -0.040859
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0407964
NAMPT nicotinamide phosphoribosyltransferase -0.0407606
FAM13A family with sequence similarity 13, member A -0.0388676
RPLP0 ribosomal protein, large, P0 -0.0385072
WDR45B WD repeat domain 45B -0.0376447
RPL38 ribosomal protein L38 -0.0374053
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0369324
PCDH9 protocadherin 9 -0.03676
B2M beta-2-microglobulin -0.0365865
NPEPPS aminopeptidase puromycin sensitive -0.0355616
RPL31 ribosomal protein L31 -0.0352945
SOS1 son of sevenless homolog 1 (Drosophila) -0.0342502
FAM162A family with sequence similarity 162, member A -0.0334768
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0328115
NDRG1 N-myc downstream regulated 1 -0.03245
IER3 immediate early response 3 -0.0323028
RPS8 ribosomal protein S8 -0.030643
RPL23 ribosomal protein L23 -0.03053
DCAF7 DDB1 and CUL4 associated factor 7 -0.0287522
OGA O-GlcNAcase -0.0278009
GNAS GNAS complex locus -0.0276597
RPL32 ribosomal protein L32 -0.0275798
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0270167
SYT1 synaptotagmin I -0.0267996
H3-3B H3.3 histone B -0.0265917
RPS11 ribosomal protein S11 -0.0264738
KDM3A lysine (K)-specific demethylase 3A -0.0261318
RPS5 ribosomal protein S5 -0.0261218
LMNA lamin A/C -0.0259948
NME2 NME/NM23 nucleoside diphosphate kinase 2 -0.025858
FTL ferritin, light polypeptide -0.0251176
RPL27 ribosomal protein L27 -0.0247487
RAD21 RAD21 homolog (S. pombe) -0.0243614
CCNI cyclin I -0.024238
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0240726
AHNAK AHNAK nucleoprotein -0.0239871
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0231499
GPBP1 GC-rich promoter binding protein 1 -0.0228125
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.0224886
EYA1 EYA transcriptional coactivator and phosphatase 1 -0.0223906
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0223758
RPS19 ribosomal protein S19 -0.0223178
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0222242
VDAC1 voltage-dependent anion channel 1 -0.0222206
RPL36A ribosomal protein L36a -0.0221839
PRR11 proline rich 11 -0.0221467
S100A6 S100 calcium binding protein A6 -0.0217383
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0212325
SCAF11 SR-related CTD-associated factor 11 -0.0212115
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0212059
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0207675
RPLP2 ribosomal protein, large, P2 -0.0203232
CSDE1 cold shock domain containing E1, RNA-binding -0.0202704
RPL8 ribosomal protein L8 -0.0197831
CCDC47 coiled-coil domain containing 47 -0.0197611
CENPF centromere protein F, 350/400kDa -0.0195422
MARCKS myristoylated alanine-rich protein kinase C substrate -0.019409
LUM lumican -0.0193997
RPL7 ribosomal protein L7 -0.019316
ADGRG6 adhesion G protein-coupled receptor G6 -0.0192886
RPL36 ribosomal protein L36 -0.0188941
CD36 CD36 molecule (thrombospondin receptor) -0.0188296
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0186386
RIOK3 RIO kinase 3 -0.01837
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0183354
KMT2A lysine (K)-specific methyltransferase 2A -0.018084
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0180364
RPL35 ribosomal protein L35 -0.0179999
UBC ubiquitin C -0.0176012
BIRC2 baculoviral IAP repeat containing 2 -0.0174609
RPS21 ribosomal protein S21 -0.0173165
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.017291
S100A9 S100 calcium binding protein A9 -0.0172477
OTUD7B OTU deubiquitinase 7B -0.0171191
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0170068
FKBP10 FK506 binding protein 10, 65 kDa -0.0169898
RBM39 RNA binding motif protein 39 -0.0169555
SEC23A Sec23 homolog A (S. cerevisiae) -0.0166366
RPL12 ribosomal protein L12 -0.016611
ASTN2 astrotactin 2 -0.0164865
HELZ helicase with zinc finger -0.0164832
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0164728
ARF1 ADP-ribosylation factor 1 -0.0163134