| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.101367 |
| APP | amyloid beta (A4) precursor protein | 0.0912008 |
| LDHA | lactate dehydrogenase A | 0.0669384 |
| EGFR | epidermal growth factor receptor | 0.0617824 |
| TMSB4X | thymosin beta 4, X-linked | 0.0615511 |
| ANXA1 | annexin A1 | 0.0603789 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0546105 |
| KRT7 | keratin 7, type II | 0.0511907 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.050254 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0475484 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0474547 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0464442 |
| TXNRD1 | thioredoxin reductase 1 | 0.0432136 |
| ENO1 | enolase 1, (alpha) | 0.0391528 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0383457 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0376934 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0364419 |
| WDR43 | WD repeat domain 43 | 0.0358414 |
| RNF145 | ring finger protein 145 | 0.0353656 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0349741 |
| RPL3 | ribosomal protein L3 | 0.0349034 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0344178 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0341634 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0340209 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0334087 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0333849 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0332398 |
| MATR3 | matrin 3 | 0.0329343 |
| PKM | pyruvate kinase, muscle | 0.0328568 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0304569 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0295132 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0294218 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0294056 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0293887 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0290005 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0285808 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274821 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0270022 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0267286 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0265341 |
| FNBP1L | formin binding protein 1-like | 0.0263158 |
| ANKRD10 | ankyrin repeat domain 10 | 0.025902 |
| CCNL1 | cyclin L1 | 0.0258054 |
| LMNA | lamin A/C | 0.0256157 |
| TFRC | transferrin receptor | 0.0255485 |
| USP3 | ubiquitin specific peptidase 3 | 0.0255442 |
| RPL13A | ribosomal protein L13a | 0.0253505 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0252915 |
| POU5F1 | POU class 5 homeobox 1 | 0.0252284 |
| TES | testin LIM domain protein | 0.0251888 |
| VEGFA | vascular endothelial growth factor A | 0.0248089 |
| HKDC1 | hexokinase domain containing 1 | 0.0247333 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.024678 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0244225 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0243251 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0241823 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0240714 |
| VMP1 | vacuole membrane protein 1 | 0.0233266 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0232076 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0231693 |
| UTRN | utrophin | 0.0231422 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0229163 |
| EREG | epiregulin | 0.0229055 |
| CLDN1 | claudin 1 | 0.0228822 |
| TNS3 | tensin 3 | 0.0228429 |
| TCERG1 | transcription elongation regulator 1 | 0.022804 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0226382 |
| KRT18 | keratin 18, type I | 0.0226068 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0225729 |
| RANBP2 | RAN binding protein 2 | 0.0223945 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0223733 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0222913 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0222726 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0222595 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0221809 |
| PATJ | PATJ crumbs cell polarity complex component | 0.022162 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0219458 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0219343 |
| CD47 | CD47 molecule | 0.0219167 |
| PUM1 | pumilio RNA-binding family member 1 | 0.021903 |
| TCF12 | transcription factor 12 | 0.0218056 |
| TULP4 | tubby like protein 4 | 0.0217122 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0216476 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0216263 |
| SLTM | SAFB-like, transcription modulator | 0.0213983 |
| TRIM2 | tripartite motif containing 2 | 0.0213624 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0213425 |
| GLIS3 | GLIS family zinc finger 3 | 0.0213165 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0212927 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0212792 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0212429 |
| NCKAP1 | NCK-associated protein 1 | 0.0210953 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0209285 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.020927 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0208945 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0205211 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0204683 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0204624 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0203163 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0203111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.257867 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.155364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.118507 |
| PRELID2 | PRELI domain containing 2 | -0.1129 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110204 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.107432 |
| FHIT | fragile histidine triad | -0.0884986 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0806289 |
| FTL | ferritin, light polypeptide | -0.0792341 |
| RPS19 | ribosomal protein S19 | -0.0772777 |
| MT2A | metallothionein 2A | -0.0770304 |
| WWOX | WW domain containing oxidoreductase | -0.0736438 |
| RAD51B | RAD51 paralog B | -0.0718001 |
| ACTG1 | actin gamma 1 | -0.0703824 |
| MACROD2 | MACRO domain containing 2 | -0.06761 |
| RPLP1 | ribosomal protein, large, P1 | -0.064479 |
| TMSB10 | thymosin beta 10 | -0.0642651 |
| RPL23 | ribosomal protein L23 | -0.0639234 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0638142 |
| RPL35A | ribosomal protein L35a | -0.0628589 |
| RPS6 | ribosomal protein S6 | -0.0627827 |
| RPL12 | ribosomal protein L12 | -0.0627624 |
| RPS8 | ribosomal protein S8 | -0.0581513 |
| ASPH | aspartate beta-hydroxylase | -0.0555684 |
| S100A10 | S100 calcium binding protein A10 | -0.0555464 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0541318 |
| RPL32 | ribosomal protein L32 | -0.0512552 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0499371 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0480542 |
| RUNX1 | runt-related transcription factor 1 | -0.0471753 |
| VCL | vinculin | -0.0471337 |
| SNX14 | sorting nexin 14 | -0.0469887 |
| S100A9 | S100 calcium binding protein A9 | -0.0439383 |
| TJP1 | tight junction protein 1 | -0.0424492 |
| CDCP1 | CUB domain containing protein 1 | -0.0420928 |
| RPLP0 | ribosomal protein, large, P0 | -0.0418082 |
| RPL31 | ribosomal protein L31 | -0.0414301 |
| OGA | O-GlcNAcase | -0.0401325 |
| RPL19 | ribosomal protein L19 | -0.0399342 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0392582 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0390368 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0388723 |
| BBX | bobby sox homolog (Drosophila) | -0.0386034 |
| FLNA | filamin A, alpha | -0.0385499 |
| RPL35 | ribosomal protein L35 | -0.0383182 |
| HMGB1 | high mobility group box 1 | -0.0370844 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0365864 |
| CENPF | centromere protein F, 350/400kDa | -0.0353006 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0352274 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0351741 |
| DIAPH3 | diaphanous-related formin 3 | -0.035139 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0349369 |
| METTL15 | methyltransferase like 15 | -0.0340898 |
| ANLN | anillin, actin binding protein | -0.0340085 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0339763 |
| RPL28 | ribosomal protein L28 | -0.0338704 |
| RPS12 | ribosomal protein S12 | -0.0338551 |
| INTS6 | integrator complex subunit 6 | -0.0337404 |
| ECT2 | epithelial cell transforming 2 | -0.033629 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0330797 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0323433 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0319523 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0317077 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0313459 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0305208 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0304002 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0302461 |
| WWC1 | WW and C2 domain containing 1 | -0.0301186 |
| RPS27 | ribosomal protein S27 | -0.0300491 |
| AHNAK | AHNAK nucleoprotein | -0.0300433 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0299027 |
| RPS11 | ribosomal protein S11 | -0.0297958 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0293275 |
| MT1X | metallothionein 1X | -0.0292934 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0292884 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0292716 |
| RSF1 | remodeling and spacing factor 1 | -0.0291288 |
| RAB3IP | RAB3A interacting protein | -0.0290799 |
| RPL11 | ribosomal protein L11 | -0.0290616 |
| RPLP2 | ribosomal protein, large, P2 | -0.0288535 |
| SPAG9 | sperm associated antigen 9 | -0.0287709 |
| JMJD1C | jumonji domain containing 1C | -0.0286857 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0282407 |
| TUSC3 | tumor suppressor candidate 3 | -0.0280645 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0280483 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0279899 |
| RPL36 | ribosomal protein L36 | -0.0278988 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0278966 |
| MYO1E | myosin IE | -0.0276552 |
| RPS14 | ribosomal protein S14 | -0.0274841 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0274297 |
| RPS15 | ribosomal protein S15 | -0.0274079 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0273889 |
| LNPK | lunapark, ER junction formation factor | -0.026819 |
| RASA2 | RAS p21 protein activator 2 | -0.0267869 |
| RPL34 | ribosomal protein L34 | -0.0266389 |
| XPO1 | exportin 1 | -0.026605 |
| MKI67 | marker of proliferation Ki-67 | -0.0265058 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0264193 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.026249 |
